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Sökning: WFRF:(Jonsson Anders) > Göteborgs universitet

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61.
  • Jonsson, Mattias, et al. (författare)
  • Cost-effectiveness of silvicultural measures to increase substrate availability for red-listed wood-living organisms in Norway spruce forests
  • 2006
  • Ingår i: Biological Conservation. - : Elsevier. - 0006-3207 .- 1873-2917. ; 127:4, s. 443-467
  • Tidskriftsartikel (refereegranskat)abstract
    • It is important that measures to maintain biodiversity are taken in a way that is cost-effective for the landowner. We analyzed the cost-effectiveness of silvicultural measures that aim at increasing the substrate availability for red-listed (species that are threatened, near threatened or where species probably are threatened but data is deficient) saproxylic (wood-inhabiting) organisms. We modelled stands of Norway spruce (Picea abies) in three regions of Sweden by using computer simulations and a database with substrate requirements of saproxylic beetles and cryptogams on the Swedish Red-List. Conclusions concerning cost-effectiveness of silvicultural measures depend on the extinction thresholds of the species they are intended to conserve; measures that generate only small amounts of coarse woody debris (CWD) may provide too little substrate to be useful for species with high extinction thresholds. In northern Sweden, forestland is relatively inexpensive, so a cost-effective strategy to increase the amount of spruce CWD was to set aside more forests as reserves. In central and southern Sweden, more emphasis should instead be given to increasing the amount of CWD in the managed forest. The regulations by the Forest Stewardship Council (FSC) could be made more cost-effective by prescribing creation of more high stumps and retention of larger amounts of naturally dying trees. Large-sized CWD, CWD from slow-growing trees, and CWD in late decay stages are substrate types that were particularly rare in managed forest in relation to unmanaged forests. Manual soil scarification and retention of living trees are measures that can increase the proportion of these underrepresented CWD types.
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62.
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63.
  • Jonsson, Michael, 1955, et al. (författare)
  • Low Cerebrospinal Fluid Sulfatide Predicts Progression of White Matter Lesions - The LADIS Study
  • 2012
  • Ingår i: Dementia and Geriatric Cognitive Disorders. - : S. Karger AG. - 1420-8008 .- 1421-9824. ; 34:1, s. 61-67
  • Tidskriftsartikel (refereegranskat)abstract
    • Background/Aims: Demyelination and axonal degeneration are the hallmarks of established white matter lesions (WML). The neurochemistry of ongoing WML is only partially known. We explored cerebrospinal fluid (CSF) substances as markers of brain tissue damage in relation to progression of WML rated on magnetic resonance imaging. Methods: CSF from elderly individuals with WML was analyzed for amyloid markers, total tau, hyperphosphorylated t, neurofilament protein light subunit, sulfatide and CSF/serum-albumin ratio. After 3 years, a follow-up magnetic resonance imaging was performed. Progression of WML was rated using the Rotterdam Progression Scale (RPS). Results: 37 subjects (age 73.6 +/- 4.6 years) were included. Subjects with more pronounced progression (RPS > 2; n = 15) had lower mean sulfatide concentration at baseline as compared to subjects with no or minimal progression (RPS 0-2; n = 22) according to univariate analyses (p = 0.009). Sulfatide was the only biomarker that predicted the RPS score according to regression analysis, explaining 18.9% of the total variance (r = 0.38, p = 0.015). Conclusion: The correlation of CSF sulfatide levels and RPS scores may reflect a remyelination response to the demyelination process associated with WML. Furthermore, the results strengthen the notion that WML pathology is different from that of Alzheimer's disease.
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64.
  • Jonsson, Nino, et al. (författare)
  • Factors associated with treatment limitations in two Swedish intensive care units : Prevalence and patient involvement
  • 2023
  • Ingår i: Acta Anaesthesiologica Scandinavica. - : John Wiley & Sons. - 0001-5172 .- 1399-6576. ; 67:3, s. 339-346
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim was to study the prevalence, documentation, and patient involvement in treatment limitations (TLs) in two Swedish intensive care units (ICUs). All patients admitted to the ICUs of two Swedish regional hospitals in 2019 were screened for inclusion. Exclusion criteria included postanesthesia care < 24 h. Patients were identified using the Swedish Intensive Care Registry (SIR) and data were extracted from SIR and hospital charts. Uni- and multivariable logistic analysis was performed to investigate associations with the presence of TLs. A total of 3090 patients were admitted to the two ICUs in 2019. After exclusion, 1019 patients were included in the study. 45.5% were women and the mean age was 62.9 years. 26.5% of the patients had one or several TLs. Age (OR 1.04 per one year increase 95% confidence interval (CI) 1.02-1.05), SAPS3-score (OR 1.08 per one unit increase 95% CI 1.06-1.09) and ICU length of stay (OR 1.11 per one day increase 95% CI 1.05-1.17) were independently associated with an increased likelihood of receiving a TL. 17% of the patients were involved in the decision-making process and in > 30% of cases neither the patient nor next-of-kin were informed. Women were to a larger extent involved in the decision process than men (24.5 vs. 12.5% p < .05). When the intensivist documented why a TL was established, patient autonomy was four times more commonly stated as the motivation for the TL among women compared to men (15.5% vs. 3.8% p < .05). TLs were common in two Swedish ICUs but a substantial number of patients and next-of-kin were not involved in the decision-making process or informed of the decision. Women were more often than men engaged in the decision to establish a TL.
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65.
  • Jonsson, Olof, 1941, et al. (författare)
  • Enhanced post-ischaemic recovery in rabbit kidney after pretreatment with an indeno-indole compound and ascorbate monitored in vivo by 31P magnetic resonance spectroscopy.
  • 2003
  • Ingår i: Scandinavian Journal of Urology and Nephrology. - 0036-5599. ; 37:6, s. 450-455
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To investigate whether combined pretreatment with lipid- and water-soluble antioxidants gave better restoration of energy phosphates after ischaemia–reperfusion of rabbit kidneys than single pretreatment with a lipid-soluble antioxidant. Material and Methods: Thirteen New Zealand white rabbits were used for the study. Changes in energy phosphates were measured in vivo using volume-selective 31P magnetic resonance spectroscopy. The indeno–indole compound H290/51 was chosen as a lipid-soluble antioxidant and ascorbate as a water-soluble antioxidant. Results: The combined pretreatment led to significantly better restoration of the β-adenosine triphosphate:inorganic phosphate ratio after 60 min of ischaemia and 120 min of reperfusion compared with the single pretreatment. Analyses of blood pressure and blood gas changes showed that the beneficial effect of combined pretreatment was not caused by a better general condition of the animals in that group but by a direct effect on the kidneys. Conclusions: Combined pretreatment with lipid- and water-soluble antioxidants leads to better restoration of energy phosphates in rabbit kidneys subjected to ischaemia–reperfusion compared with single pretreatment with a lipid-soluble antioxidant.
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66.
  • Jonsson, Per R., 1957, et al. (författare)
  • The Barnacle Balanus improvisus as a Marine Model - Culturing and Gene Expression
  • 2018
  • Ingår i: Jove-Journal of Visualized Experiments. - : MyJove Corporation. - 1940-087X. ; :138
  • Tidskriftsartikel (refereegranskat)abstract
    • Barnacles are marine crustaceans with a sessile adult and free-swimming, planktonic larvae. The barnacle Balanus (Amphibalanus) improvisus is particularly relevant as a model for the studies of osmoregulatory mechanisms because of its extreme tolerance to low salinity. It is also widely used as a model of settling biology, in particular in relation to antifouling research. However, natural seasonal spawning yields an unpredictable supply of cyprid larvae for studies. A protocol for the all-year-round culturing of B. improvisus has been developed and a detailed description of all steps in the production line is outlined (i.e., the establishment of adult cultures on panels, the collection and rearing of barnacle larvae, and the administration of feed for adults and larvae). The description also provides guidance on troubleshooting and discusses critical parameters (e.g., the removal of contamination, the production of high-quality feed, the manpower needed, and the importance of high-quality seawater). Each batch from the culturing system maximally yields roughly 12,000 nauplii and can deliver four batches in a week, so up to almost 50,000 larvae per week can be produced. The method used to culture B. improvisus is, probably, to a large extent also applicable to other marine invertebrates with free-swimming-larvae. Protocols are presented for the dissection of various tissues from adults as well as the production of high-quality RNA for studies on gene expression. It is also described how cultured adults and reared cyprids can be utilized in a wide array of experimental designs for examining gene expression in relation to external factors. The use of cultured barnacles in gene expression is illustrated with studies of possible osmoregulatory roles of Na+/K+ ATPase and aquaporins.
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67.
  • Jónsson, Sverrir Aðalsteinn, et al. (författare)
  • The drumlin field and the geomorphology of the Múlajökull surge-type glacier, central Iceland
  • 2014
  • Ingår i: Geomorphology. - : Elsevier BV. - 0169-555X .- 1872-695X. ; 207, s. 213-220
  • Tidskriftsartikel (refereegranskat)abstract
    • Here we present a new geomorphological map of the active drumlin field and the forefield of Múlajökull, a surge-type outlet glacier, Iceland. The map is based on aerial photographs taken in 1995 and LiDAR data recorded in 2008. Mapping was done using ArcGIS 10 software on orthorectified imagery, LiDAR data and digital elevation models. The mapped landforms were initially identified on the aerial imagery and LiDAR and then ground-checked in the field. We mapped subglacial, supraglacial, ice-marginal, periglacial, and glaciofluvial landforms. The geomorphology of the Múlajökull forefield is similar to that of the forefields of other surge-type glaciers in Iceland: with a highly streamlined forefield, crevasse-fill ridges, and series of glaciotectonic end moraines. However, the large number (i.e., 110) of drumlins forming the drumlin field is unique for modern Icelandic surge-type glaciers and, as yet, unique for contemporary glaciers in general. Also apparent is that the drumlins are wider and shorter in the distal part of the drumlin field and narrower and longer in the proximal part. Hence, the mapping reveals a development of the drumlins toward a more streamlined shape of the proximal landforms that have experienced more surges. The drumlins in the drumlin field are active, i.e., they form during the modern surges of Múlajökull.
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68.
  • Jonsson, Sverrir, et al. (författare)
  • THE MÚLAJÖKULL DRUMLIN FIELD - SEDIMENTOLOGY AND GEOMORPHOLOGY
  • 2011
  • Ingår i: Geological Society of America abstracts with programs Minneapolis 2011.
  • Konferensbidrag (refereegranskat)abstract
    • The drumlin field in front of Múlajökull, a surge-style, outlet glacier from Hofsjökull in Iceland, is the only known active drumlin field (Johnson et al., 2010). The aim of this study is to further explore the formation of drumlins in a modern glacial environment. We use data from geological sections, DEMs, aerial imagery and field mapping. Here we present preliminary results from section logging and geomorphological mapping in the summer of 2011. Geomorphological mapping of the drumlin field both with DEMs and ground proofing has revealed over 100 drumlins and a number of drumlinized ridges. The drumlins furthest from the present ice margin appear broader and have lower relief than those closer to the ice. We suggest that this reflects an evolution of the drumlin form during recurrent surging. The drumlins farther away from the ice have experienced fewer surges than those that have just been uncovered due to retreat of the ice margin. During successive surges, the drumlins become narrower and develop higher relief. In one section close to the present ice margin, we identified at least 9 till beds in the crest of a drumlin, each likely the product of a surge, representing approximately 1/3 of the drumlin relief. The top till bed parallels the drumlin form and truncates the older tills. The older units also dip parallel to the drumlin form, but at a slightly lower angle. We believe that this represents an earlier, broader shape of the drumlin prior to the more recent surges, implying an evolution of form similar to that seen in the evolution in form in the drumlin field. The Múlajökull drumlins have thus grown during surging by erosion on the proximal end and sides of the drumlin followed by accretion of till sheets concentrically on the resulting form.
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69.
  • Kanis, John A, et al. (författare)
  • Assessment of fracture risk.
  • 2005
  • Ingår i: Osteoporosis international. - : Springer Science and Business Media LLC. - 0937-941X .- 1433-2965. ; 16:6, s. 581-9
  • Tidskriftsartikel (refereegranskat)abstract
    • The diagnosis of osteoporosis is based on the measurement of bone mineral density (BMD). There are a number of clinical risk factors that provide information on fracture risk over and above that given by BMD. The assessment of fracture risk thus needs to be distinguished from diagnosis to take account of the independent value of the clinical risk factors. These include age, a prior fragility fracture, a parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis. The independent contribution of these risk factors can be integrated by the calculation of fracture probability with or without the use of BMD. Treatment can then be offered to those identified to have a fracture probability greater than an intervention threshold.
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70.
  • Karlsson, Camilla, 1977, et al. (författare)
  • Notch and HES5 are regulated during human cartilage differentiation.
  • 2007
  • Ingår i: Cell and tissue research. - : Springer Science and Business Media LLC. - 0302-766X .- 1432-0878. ; 327:3, s. 539-51
  • Tidskriftsartikel (refereegranskat)abstract
    • The molecular mechanisms of cartilage differentiation are poorly understood. In a variety of tissues other than cartilage, members of the basic helix-loop-helix (bHLH) family of transcription factors have been demonstrated to play critical roles in differentiation. We have characterized the human bHLH gene HES5 and investigated its role during chondrogenesis. Blockage of the Notch signaling pathway with a gamma-secretase inhibitor has demonstrated that the human HES5 gene is a downstream marker of Notch signaling in articular chondrocytes. Markers for the Notch signaling pathway significantly decrease during cartilage differentiation in vitro. Cell proliferation assayed by using BrdU has revealed that blockage of Notch signaling is associated with significantly decreased proliferation. Northern blot and reverse transcription/polymerase chain reaction of a panel of various tissues have shown that HES5 is transcribed as a 5.4-kb mRNA that is ubiquitously expressed in diverse fetal and adult tissues. Articular cartilage from HES5(-/-) and wild-type mice has been analyzed by using various histological stains. No differences have been detected between the wild-type and HES5(-/-) mice. Our data thus indicate that the human HES5 gene is coupled to the Notch receptor family, that expression of Notch markers (including HES5) decreases during cartilage differentiation, and that the blockage of Notch signaling is associated with significantly decreased cell proliferation.
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