| 43701. |
- Kazemitabar, M., et al.
(författare)
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Development and primary validation of the School Health Assessment Tool for Primary Schools (SHAT-PS)
- 2021
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Ingår i: Peerj. - : PeerJ. - 2167-8359. ; 9
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Tidskriftsartikel (refereegranskat)abstract
- Background. School health programs need to target all aspects of physical, psycholog-ical, and social well-being. Using a slightly modified version of the COSMIN Risk of Bias checklist, we developed and conducted the first validation of the School Health Assessment Tool for Primary Schools (SHAT-PS). Method. The exploratory sequential mixed method was used in this study. In the first phase, scientific databases were systematically searched to find school health models and instruments and 65 interviews were conducted with school stakeholders. The Colaizzi's method was used to code the qualitative data into themes. Then, a pool of items was created for each theme, rechecked by psychometric experts and then validated for content (i.e., relevance, clarity, and comprehensiveness) by psychometric experts and individuals of the target population (i.e., school personnel). In the second phase, classical test theory was utilized to analyze the validity and reliability of the resulting items from phase 1 among 400 individuals working at primary schools. Results. The coding of the interviews resulted in ten themes that we labeled based on the theoretical literature: school health policies, community connections, health education, physical activity, health services, nutrition, psychological services, physical environment, equipment and facilities, and school staff's health. The items created for each theme ended up in an initial pool of 76 items. In the final stage of phase 1, 69 items remained after the content validity assessment by experts and school personnel. In phase 2, the SHAT-PS items were tested using maximum likelihood exploratory factor analysis and confirmatory factor analysis. Of the 69 items from phase 1, 22 items were removed due to low factor loadings. The results showed that the 8-factor model was the best solution (chi-square/df = 2.41, CFI = .98, TLI = .97, RMSEA = .06). The discriminant and convergent validity of the SHAT-PS were evaluated as satisfactory and the scale had high internal consistency (Cronbach's alpha for all subscales > .93). The test-retest reliability was satisfactory-the intraclass correlation coefficient pooled was .95 (99% CI [.91-.98]). Moreover, the standard error of measurement resulted in an SEM pooled equal to 4.4. No discrepancy was found between subgroups of gender and subgroups of staffs' positions at schools. Conclusion. The SHAT-PS is a valid and reliable tool that may facilitate school staff, stakeholders and researchers to evaluate the presence of the factors that promote health at primary schools. Nevertheless, in the process of validation, many of the items related to staff's health were eliminated due to poor factor loadings. Obviously, staff health is an important factor in the measurement of school health. Hence, we recommend that the validity and reliability of the SHAT-PS in other cultures should be done using the original 76-item version.
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| 43702. |
- Kazemitabar, Maryam, et al.
(författare)
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Does auditory attentional bias determine craving for methamphetamine? A pilot study using a word recognition dichotic listening task
- 2022
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Ingår i: Heliyon. - : Elsevier BV. - 2405-8440. ; 8:11, s. 1-7
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Obtaining reliable data under explicit evaluations is one of the most complicated challenges in assessing drug users' status. Respondents are likely to give answers that are to their advantage or deliberately deceitful. Regarding drug use, intense and inevitable drug craving is known as one of the main causes of relapse and treatment failure. As a matter of fact, drug craving is directly correlated to attentional bias toward drug-related stimuli, while drug-related stimuli capture drug users' attention as a result of craving. Most methods for studying selective attention and attentional bias have been developed for visual modality. However, stimuli that capture drug users’ attention are not always visual, they could be auditory. AIMS: We examined if a modified word recognition dichotic listening task discriminated between methamphetamine users and non-users. Moreover, we investigated further the reliability and validity of this new paradigm. METHODS: A total of 30 adult males participated in the study (15 methamphetamine users and 15 non-users). The word recognition dichotic listening task included two stimuli narratives/sequences (one neutral and one methamphetamine-related) that were presented simultaneously via headphones, one stimuli sequence to each ear. The participants were instructed to only pay attention to the neutral stimuli and to ignore the drug-related stimuli. Afterward, participants were asked to indicate in a list which words they recognized from the listening task and responded to the Desire for Drug Questionnaire, which was modified to address methamphetamine craving. In addition, a month after the experiment, we assessed therapy adherence among participants who were methamphetamine users. RESULTS: Methamphetamine users had a significantly lower performance in the word recognition dichotic task compared to non-users (t = 4.30, p < .001; Cohen’s d = 6.13). Importantly, the average performance on the task was significantly higher among methamphetamine users who continued their treatment one month later compared to those who quitted (t = −2.56, p < .05; Hedges' g = 1.28). Moreover, the intraclass correlation coefficient with 95% interval confidence for the word recognition dichotic listening task scores was excellent (ICC = 0.90) and the scores were significantly correlated with self-reported methamphetamine craving (r = −.47, p < .001). CONCLUSIONS: The modified word recognition dichotic listening task successfully discriminated between individuals who craved methamphetamine from those who did not. This new paradigm demonstrated high reliability and validity in the present pilot study. Due to the importance of preventing unreliable responses when assessing drug cravings, the current method can be, after further validation, utilized in both research and clinical practices.
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| 43703. |
- Kazemitabar, Maryam, et al.
(författare)
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Translation and psychometric validation of the Persian version of the Questionnaire on Smoking Urges for assessment of craving to smoke among university students
- 2021
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Ingår i: PeerJ. - : PeerJ. - 2167-8359. ; 9
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Tidskriftsartikel (refereegranskat)abstract
- Background. Even though tobacco is one of the most preventable causes of death worldwide, it endangers more than 8 million people yearly. In this context, meta-analyses suggest that a significant part of the general Iranian population over 15 years of age smoke and that there is a need for good screening tools for smoking cravings and urges in Iran. The present study reported the translation and investigated the psychometric properties (i.e., factor structure, validity, and reliability) of the Persian version of the Questionnaire on Smoking Urges (QSU) with 12 items in the Iranian context. Method. The translation process and content validity of the items were examined entirely in an expert panel using the Content Validity Index. The total sample of participants in which the translated version was tested consisted of 392 (172 female, 220 male, Mage = 22.31 years, SD = 2.90) university students who answered the QSU 12-item at the start of their participation in smoking cessation interventions. The QSU 12-item was firstly translated, then piloted using a subsample of 150 university students and finally validity and reliability of the instrument were investigated using a subsample of 242 participants. We tested the proposed models in the literature, that is, a 1-factor solution and a 2-factor solution with six items on each factor (Factor 1: desire/intention to smoke; Factor 2: relief of negative affect or withdrawal symptoms and anticipation of positive outcome). At last, we tested differences across differences in QSU-scores across different subgroups of individuals based on their demographics. Results. The results suggested that, in contrast to past studies, a modified 2-factor model, using five items for Factor 1 and 7 items for Factor 2, was the best fitting model (CFI =.95, RMSEA =.09, CI = 90%). Additionally, the QSU 12-item Persian version showed good convergent and divergent validity, internal consistency (Factor 1 =.94, Factor 2 =.97), ICC (average measure ICC =.95, CI = 95%, F(391, 4301) = 20.54, p <.001), concurrent validity (r =.71, p <.01), and discriminant validity (r = -.04, p >.05). Finally, subgroups based on gender, marital status, (un)employment, and educational level did not differed in their responses to the QSU 12-item. Conclusion. The Persian version of the QSU 12-item has satisfactory psychometric properties and, with a slight modification, it can be considered as a reliable and valid method to estimate smoking urges in the Iranian population. Moreover, the QSU 12-item seems appropriate to measure urge for smoking among groups of individuals with different sociodemographic backgrounds. Importantly, the QSU 12-item differentiates individuals' desire and intention to smoke from their anticipated relief of negative affect or withdrawal symptoms, which can be important for personalizing interventions targeting individuals who want to quit smoking.
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| 43704. |
- Kazemzadeh, Laleh, et al.
(författare)
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Boolean model of yeast apoptosis as a tool to study yeast and human apoptotic regulations
- 2012
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Ingår i: Frontiers in Physiology. - : Frontiers Media SA. - 1664-042X. ; 3
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Tidskriftsartikel (refereegranskat)abstract
- Programmed cell death (PCD) is an essential cellular mechanism that is evolutionary conserved, mediated through various pathways and acts by integrating different stimuli. Many diseases such as neurodegenerative diseases and cancers are found to be caused by, or associated with, regulations in the cell death pathways. Yeast Saccharomyces cerevisiae, is a unicellular eukaryotic organism that shares with human cells components and pathways of the PCD and is therefore used as a model organism. Boolean modeling is becoming promising approach to capture qualitative behavior and describe essential properties of such complex networks. Here we present large literature-based and to our knowledge first Boolean model that combines pathways leading to apoptosis (a type of PCD) in yeast. Analysis of the yeast model confirmed experimental findings of anti-apoptotic role of Bir1p and pro-apoptotic role of Stm1p and revealed activation of the stress protein kinase Hog proposing the maximal level of activation upon heat stress. In addition we extended the yeast model and created an in silico humanized yeast in which human pro- and anti-apoptotic regulators Bcl-2 family and Valosin-contain protein (VCP) are included in the model. We showed that accumulation of Bax in silico humanized yeast shows apoptotic markers and that VCP is essential target of Akt Signaling. The presented Boolean model provides comprehensive description of yeast apoptosis network behavior. Extended model of humanized yeast gives new insights of how complex human disease like neurodegeneration can initially be tested.
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| 43705. |
- Kazimierczuk, Krzysztof, et al.
(författare)
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A comparison of convex and non-convex compressed sensing applied to multidimensional NMR
- 2012
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Ingår i: Journal of Magnetic Resonance. - : Elsevier BV. - 1090-7807. ; 223, s. 1-10
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Tidskriftsartikel (refereegranskat)abstract
- The resolution of multidimensional NMR spectra can be severely limited when regular sampling based on the Nyquist-Shannon theorem is used. The theorem binds the sampling rate with a bandwidth of a sampled signal and thus implicitly creates a dependence between the line width and the time of experiment, often making the latter one very long. Recently, Candes et al. (2006)[25] formulated a non-linear sampling theorem that determines the required number of sampling points to be dependent mostly on the number of peaks in a spectrum and only slightly on the number of spectral points. The result was pivotal for rapid development and broad use of signal processing method called compressed sensing. In our previous work, we have introduced compressed sensing to multidimensional NMR and have shown examples of reconstruction of two-dimensional spectra. In the present paper we discuss in detail the accuracy and robustness of two compressed sensing algorithms: convex (iterative soft thresholding) and non-convex (iteratively re-weighted least squares with local l(0)-norm) in application to two- and three-dimensional datasets. We show that the latter method is in many terms more effective, which is in line with recent works on the theory of compressed sensing. We also present the comparison of both approaches with multidimensional decomposition which is one of the established methods for processing of non-linearly sampled data. (C) 2012 Elsevier Inc. All rights reserved.
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| 43706. |
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| 43707. |
- Kazimierczuk, Krzysztof, et al.
(författare)
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Non-uniform sampling: Post-Fourier era of NMR data collection and processing
- 2015
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Ingår i: Magnetic Resonance in Chemistry. - : Wiley. - 0749-1581 .- 1097-458X. ; 53:11, s. 921-926
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Tidskriftsartikel (refereegranskat)abstract
- The invention of multidimensional techniques in the 1970s revolutionized NMR, making it the general tool of structural analysis of molecules and materials. In the most straightforward approach, the signal sampling in the indirect dimensions of a multidimensional experiment is performed in the same manner as in the direct dimension, i.e. with a grid of equally spaced points. This results in lengthy experiments with a resolution often far from optimum. To circumvent this problem, numerous sparse-sampling techniques have been developed in the last three decades, including two traditionally distinct approaches: the radial sampling and non-uniform sampling. This mini review discusses the sparse signal sampling and reconstruction techniques from the point of view of an underdetermined linear algebra problem that arises when a full, equally spaced set of sampled points is replaced with sparse sampling. Additional assumptions that are introduced to solve the problem, as well as the shape of the undersampled Fourier transform operator (visualized as so-called point spread function), are shown to be the main differences between various sparse-sampling methods. Copyright © 2015 John Wiley & Sons, Ltd.
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| 43708. |
- Kazimierczuk, Krzysztof, et al.
(författare)
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Resolution enhancement in NMR spectra by deconvolution with compressed sensing reconstruction
- 2020
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1359-7345 .- 1364-548X. ; 56, s. 14585-14588
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Tidskriftsartikel (refereegranskat)abstract
- NMR spectroscopy is one of the basic tools for molecular structure elucidation. Unfortunately, the resolution of the spectra is often limited by inter-nuclear couplings. The existing workarounds often alleviate the problem by trading it for another deficiency, such as spectral artefacts or difficult sample preparation and, thus, are rarely used. We suggest an approach using the coupling deconvolution in the framework of compressed sensing (CS) spectra processing that leads to a major increase in resolution, sensitivity, and overall quality of NUS reconstruction. A new mathematical description of the decoupling by deconvolution explains the effects of thermal noise and reveals a relation with the underlying assumption of the CS. The gain in resolution and sensitivity for challenging molecular systems is demonstrated for the key HNCA experiment used for protein backbone assignment applied to two large proteins: intrinsically disordered 441-residue Tau and a 509-residue globular bacteriophytochrome fragment. The approach will be valuable in a multitude of chemistry applications, where NMR experiments are compromised by the homonuclear scalar coupling. This journal is
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| 43709. |
- Kazmierczak, Karolina, et al.
(författare)
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A case study of serial-flow car disassembly: ergonomics, productivity and potential system performance
- 2007
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Ingår i: Human Factors and Ergonomics in Manufacturing. - 1090-8471. ; 17:4, s. 331-351
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Tidskriftsartikel (refereegranskat)abstract
- A recent European Union (EU) directive increases demands on car recycling. Thus, present craft-type disassembly systems need reconfiguration in order to be more efficient. A line-based system tested in the Netherlands was investigated regarding system performance and ergonomics. The system had reduced performance compared to the design specifications due to such factors as system losses, operator inexperience, and teamwork deficiencies. Operators' peak low back loads were lower than in Swedish craft-type systems. Direct, value-adding work comprised 30% of the workday, compared to about 70% in the Swedish manufacturing industry. Alternative system configurations were simulated and discussed using a novel combination of flow and human simulations. For example, a smaller variation in cycle time implied higher output in number of cars per week and larger operator cumulative loading on the low back. In all models the cumulative load was high compared to the loads previously recorded in assembly work.
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| 43710. |
- Kazmierczak, Karolina, et al.
(författare)
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An integrated analysis of ergonomics and time consumption in Swedish 'craft-type' car disassembly.
- 2005
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Ingår i: Applied Ergonomics. - : Elsevier BV. - 0003-6870 .- 1872-9126. ; 36:3, s. 263-73
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Tidskriftsartikel (refereegranskat)abstract
- Car disassembly is at the edge of extensive rationalisations due to increased legislative demands for recycling. This study focused on (1) assessing current mechanical exposures (physical work loads) for comparison with future rationalised systems, with particular emphasis on time aspects, (2) analysing disassembly work in terms of time consumption and exposures in constituent tasks as defined by a loss analysis technique, and (3) predicting the consequences of car disassembly rationalisation for mechanical exposures. The study showed that disassembly implied pronounced circulatory loads, and that more walking and higher lumbar peak loads were found than in studies of assembly work. Value-adding tasks comprised 30% of the total working time, and implied higher postural exposures for the head, arm, trunk and wrist, as well as less opportunities to recover, as compared to non-value-adding tasks. Organisational-type rationalisations can be expected to increase the time spent in value-adding work, thus increasing local exposures for the average worker, while a concurrent increase in mechanisation level might reduce circulatory exposures, the amount of walking, and peak lumbar loads.
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