| 61. |
- Aalto, Susanne, 1964, et al.
(författare)
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13CO 1-0 imaging of the Medusa merger, NGC 4194. Large scale variations in molecular cloud properties
- 2010
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 522:5
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Tidskriftsartikel (refereegranskat)abstract
- Aims. Studying molecular gas properties in merging galaxies gives important clues to the onset and evolution of interaction-triggered starbursts. The (CO)-C-12/(CO)-C-13 line intensity ratio can be used as a tracer of how dynamics and star formation processes impact the gas properties. The Medusa merger (NGC 4194) is particularly interesting to study since its L-FIR/L-CO ratio rivals that of ultraluminous galaxies (ULIRGs), despite the comparatively modest luminosity, indicating an exceptionally high star formation efficiency (SFE) in the Medusa merger. Methods. High resolution OVRO (Owens Valley Radio Observatory) observations of the (CO)-C-13 1-0 have been obtained and compared with matched resolution OVRO (CO)-C-12 1-0 data to investigate the molecular gas cloud properties in the Medusa merger. Results. Interferometric observations of (CO)-C-12 and (CO)-C-13 1-0 in the Medusa (NGC 4194) merger show the (CO)-C-12 (CO)-C-13 1-0 intensity ratio (R) increases from normal, quiescent values (7-10) in the outer parts (r > 2 kpc) of the galaxy to high (16 to > 40) values in the central (r
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| 62. |
- Aalto, Susanne, 1964, et al.
(författare)
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H3O+ line emission from starbursts and AGNs
- 2011
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 527:8
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Tidskriftsartikel (refereegranskat)abstract
- Context. The H3O+ molecule probes the chemistry and the ionization rate of dense circumnuclear gas in galaxies. Aims. We use the H3O+ molecule to investigate the impact of starburst and AGN activity on the chemistry of the molecular interstellar medium. Methods. Using the JCMT, we have observed the 3(2)(+)-2(2)(-) 364 GHz line of p-H3O+ towards the centres of seven active galaxies. Results. We have detected p-H3O+ towards IC 342, NGC 253, NGC 1068, NGC 4418, and NGC 6240. Upper limits were obtained for IRAS 15250 and Arp 299. We find large H3O+ abundances (N(H3O+)/N(H-2) greater than or similar to 10(-8)) in all detected galaxies apart from in IC 342 where it is about one order of magnitude lower. We note, however, that uncertainties in N(H3O+) may be significant due to lack of definite information on source size and excitation. We furthermore compare the derived N(H3O+) with N(HCO+) and find that the H3O+ to HCO+ column density ratio is large in NGC 1068 ( 24), moderate in NGC 4418 and NGC 253 ( 4-5), slightly less than unity in NGC 6240 ( 0.7) and lowest in IC 342 ( 0.2-0.6). We compare our results with models of X-ray and photon dominated regions ( XDRs and PDRs). Conclusions. For IC 342 we find that a starburst PDR chemistry can explain the observed H3O+ abundance. For the other galaxies, the large H3O+ columns are generally consistent with XDR models. In particular for NGC 1068 the elevated N(H3O+)/N(HCO+) ratio suggests a low column density XDR. For NGC 4418 however, large HC3N abundances are inconsistent with the XDR interpretation. An alternative possibility is that H3O+ forms through H2O evaporating off dust grains and reacting with HCO+ in warm, dense gas. This scenario could also potentially fit the results for NGC 253. Further studies of the excitation and distribution of H3O+-aswell as Herschel observations of water abundances - will help to further constrain the models.
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| 63. |
- Aaltonen, Kristina, et al.
(författare)
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Laser capture microdissection (LCM) and whole genome amplification (WGA) of DNA from normal breast tissue - optimization for genome wide array analyses.
- 2011
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Ingår i: BMC Research Notes. - : Springer Science and Business Media LLC. - 1756-0500. ; 4, s. 69-69
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Tidskriftsartikel (refereegranskat)abstract
- Background Laser capture microdissection (LCM) can be applied to tissues where cells of interest are distinguishable from surrounding cell populations. Here, we have optimized LCM for fresh frozen normal breast tissue where large amounts of fat can cause problems during microdissection. Since the amount of DNA needed for genome wide analyses, such as single nucleotide polymorphism (SNP) arrays, is often greater than what can be obtained from the dissected tissue, we have compared three different whole genome amplification (WGA) kits for amplification of DNA from LCM material. In addition, the genome wide profiling methods commonly used today require extremely high DNA quality compared to PCR based techniques and DNA quality is thus critical for successful downstream analyses. Findings We found that by using FrameSlides without glass backing for LCM and treating the slides with acetone after staining, the problems caused by excessive fat could be significantly decreased. The amount of DNA obtained after extraction from LCM tissue was not sufficient for direct SNP array analysis in our material. However, the two WGA kits based on Phi29 polymerase technology (Repli-g® (Qiagen) and GenomiPhi (GE Healthcare)) gave relatively long amplification products, and amplified DNA from Repli-g® gave call rates in the subsequent SNP analysis close to those from non-amplified DNA. Furthermore, the quality of the input DNA for WGA was found to be essential for successful SNP array results and initial DNA fragmentation problems could be reduced by switching from a regular halogen lamp to a VIS-LED lamp during LCM. Conclusions LCM must be optimized to work satisfactorily in difficult tissues. We describe a work flow for fresh frozen normal breast tissue where fat is inclined to cause problems if sample treatment is not adapted to this tissue. We also show that the Phi29-based Repli-g® WGA kit (Qiagen) is a feasible approach to amplify DNA of high quality prior to genome wide analyses such as SNP profiling.
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| 64. |
- Aaltonen, T., et al.
(författare)
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Combination of Tevatron Searches for the Standard Model Higgs Boson in the W+W- Decay Mode
- 2010
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 104:6, s. 061802-
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Tidskriftsartikel (refereegranskat)abstract
- We combine searches by the CDF and D0 Collaborations for a Higgs boson decaying to W+W-. The data correspond to an integrated total luminosity of 4.8 (CDF) and 5.4 (D0) fb(-1) of p (p) over bar collisions at root s = 1.96 TeV at the Fermilab Tevatron collider. No excess is observed above background expectation, and resulting limits on Higgs boson production exclude a standard model Higgs boson in the mass range 162-166 GeV at the 95% C.L.
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| 65. |
- Aaltonen, T., et al.
(författare)
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Combined Tevatron upper limit on gg -> H -> W+W- and constraints on the Higgs boson mass in fourth-generation fermion models
- 2010
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Ingår i: Physical Review D. - 1550-7998. ; 82, s. 011102-
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Tidskriftsartikel (refereegranskat)abstract
- We combine results from searches by the CDF and D0 collaborations for a standard model Higgs boson (H) in the process gg -> H -> W+W- in p (p) over bar collisions at the Fermilab Tevatron Collider at root s = 1.96 TeV. With 4.8 fb(-1) of integrated luminosity analyzed at CDF and 5.4 fb(-1) at D0, the 95% confidence level upper limit on sigma(gg -> H) x B(H -> W+W-) is 1.75 pb at m(H) = 120 GeV, 0.38 pb at m(H) = 165 GeV, and 0.83 pb at m(H) = 200 GeV. Assuming the presence of a fourth sequential generation of fermions with large masses, we exclude at the 95% confidence level a standard-model-like Higgs boson with a mass between 131 and 204 GeV.
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| 66. |
- Aamaas, Borgar, et al.
(författare)
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Elemental carbon deposition to Svalbard snow from Norwegian settlements and long-range transport
- 2011
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Ingår i: Tellus. Series B, Chemical and physical meteorology. - : Stockholm University Press. - 0280-6509 .- 1600-0889. ; 63:3, s. 340-351
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Tidskriftsartikel (refereegranskat)abstract
- The impact on snow pack albedo from local elemental carbon (EC) sources in Svalbard has been investigated for the winter of 2008. Highly elevated EC concentrations in the snow are observed around the settlements of Longyearbyen and Svea (locally > 1000 ng g(-1), about 200 times over the background level), while EC concentrations similar to the background level are seen around Ny-Alesund. Near Longyearbyen and Svea, darkened snow influenced by wind transported coal dust from open coal stockpiles is clearly visible from satellite images and by eye at the ground. As a first estimate, the reduction in snow albedo caused by local EC pollution from the Norwegian settlements has been compared to the estimated reduction caused by long-range transported EC for entire Svalbard. The effect of local EC from Longyearbyen, Svea and all Norwegian settlements are estimated to 2.1%, 7.9% and 10% of the total impact of EC, respectively. The EC particles tend to stay on the surface during melting, and elevated EC concentrations due to the spring melt was observed. This accumulation of EC enhances the positive albedo feedbacks. The EC concentrations were observed to be larger in metamorphosed snow than in fresh snow, and especially around ice lenses.
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| 67. |
- Aamir, Syed Ahmed, 1980-, et al.
(författare)
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A 1.2-V pseudo-differential OTA with common-mode feedforward in 65-nm CMOS
- 2010
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Ingår i: Proceedings of the 17th IEEE International Conference on Electronics, Circuits, and Systems. - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. 29-32
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Konferensbidrag (refereegranskat)abstract
- In this work, we describe the implementation of a 1. 2-V pseudo-differential operational transconductance amplifier (OTA) with common-mode feedforward (CMFF) and inherent common-mode feedback (CMFB) in a 65-nm, digital CMOS process. The OTA architecture provides an inherent CMFB when cascaded OTA structures are utilized andthis work has studied a cascaded amplifier consisting of fourstages. Due to the low-gain using core 65-nm circuit devices, the overall gain must be distributed on all four stages to acquire a gain of more than 60 dB, while maintaining a-3-dB bandwidth of 200 MHz. To achieve high gain, we propose using a modified, positive-feedback, cross-coupled input differential stage. The modified OTA achieves a high output swing of ± 0.85 V due to only two stacked transistors, 88 dB DC gain and a third-order harmonic of -60 dB for 800 mVpp at 30 MHz. Further on, in a capacitive buffer configuration, we achieve a high slew rate of 1240 V/µS, -3-dB bandwidth of 509 MHz, signal-to-noise ratio of 63 dB while consuming 10.4 mW power.
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| 68. |
- Aamir, Syed Ahmed, 1980-, et al.
(författare)
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A 500-MHz low-voltage programmable gain amplifier for HD video in 65-nm CMOS
- 2010
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Ingår i: Proceedings of 28th IEEE Norchip Conference., NORCHIP'10. - Tampere : www.ieee.org. - 9781424489718 - 9781424489725 ; , s. 1-4
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Konferensbidrag (refereegranskat)abstract
- This work describes the implementation of a 1.2-V programmable gain amplifier (PGA) for high-definition (HD) video digitizers in a 65-nm digital CMOS process. The “pseudo” switched-capacitor (SC) PGA architecture buffers the video signal, without switching, during the active video. The SC circuitry is used for setup of DC operating point during horizontal and vertical blanking periods. Additionally, it compensates for the `sync-tip' of analog video signals to an equal blanking level for increased dynamic range to the digitizer following the PGA. The operational transconductance amplifier (OTA) employed as main amplifier in the PGA is a pseudo-differential, positive-feedback input stage architecture with a common-mode feedforward (CMFF) technique. The common-mode feedback (CMFB) is provided once two OTAs are cascaded. Schematic-level simulation results show that the OTA maintains a -3-dB bandwidth of 550 MHz, while keeping the distortion HD3 at -60 dB for a 30-MHz, 850 mVpp high definition video signal. The 88 dB DC gain is distributed among four OTA stages and the overall, combined PGA achieves a signal-to-noise ratio of 63 dB. Due to only two stacked transistors, it achieves high output swing of ±0.85 V, 1240 V/μs slew rate while consuming 10.4 mW power.
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| 69. |
- Aamodt, A., et al.
(författare)
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Case-based reasoning for assessment and diagnosis of depression in palliative care
- 2010
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Ingår i: Proceedings - IEEE Symposium on Computer-Based Medical Systems. ; , s. 480-485
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Konferensbidrag (refereegranskat)abstract
- The goal of the research presented is to create a computational framework and system architecture for clinical decision support in palliative care. The application focused is the classification of depression. The method under investigation is case-based reasoning, motivated by the complexity of the domain and a lack of generalized principles of sufficient coverage and strength for diagnosis and treatment. A system architecture is described and exemplified through an implemented prototype. The outcome of the research so far is a system that captures the properties intended, and for which a clinical test set-up has been defined. © 2010 IEEE.
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| 70. |
- Aamodt, K., et al.
(författare)
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Alignment of the ALICE Inner Tracking System with cosmic-ray tracks
- 2010
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Ingår i: Journal of Instrumentation. - 1748-0221. ; 5
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Konferensbidrag (refereegranskat)abstract
- ALICE (A Large Ion Collider Experiment) is the LHC (Large Hadron Collider) experiment devoted to investigating the strongly interacting matter created in nucleus-nucleus collisions at the LHC energies. The ALICE ITS, Inner Tracking System, consists of six cylindrical layers of silicon detectors with three different technologies; in the outward direction: two layers of pixel detectors, two layers each of drift, and strip detectors. The number of parameters to be determined in the spatial alignment of the 2198 sensor modules of the ITS is about 13,000. The target alignment precision is well below 10 mu m in some cases (pixels). The sources of alignment information include survey measurements, and the reconstructed tracks from cosmic rays and from proton-proton collisions. The main track-based alignment method uses the Millepede global approach. An iterative local method was developed and used as well. We present the results obtained for the ITS alignment using about 10(5) charged tracks from cosmic rays that have been collected during summer 2008, with the ALICE solenoidal magnet switched off.
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