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Träfflista för sökning "WFRF:(Sonestedt Emily) srt2:(2007)"

Sökning: WFRF:(Sonestedt Emily) > (2007)

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1.
  • Ericson, Ulrika, et al. (författare)
  • High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmö Diet and Cancer cohort
  • 2007
  • Ingår i: American Journal of Clinical Nutrition. - 0002-9165 .- 1938-3207. ; 86:2, s. 43-434
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Epidemiologic studies of associations between folate intake and breast cancer are inconclusive, but folate and other plant food nutrients appear protective in women at elevated risk.OBJECTIVE: The objective was to examine the association between folate intake and the incidence of postmenopausal breast cancer.DESIGN: This prospective study included all women aged >or=50 y (n = 11699) from the Malmö Diet and Cancer cohort. The mean follow-up time was 9.5 y. We used a modified diet-history method to collect nutrient intake data. At the end of follow-up, 392 incident invasive breast cancer cases were verified. We used proportional hazard regression to calculate hazard ratios (HRs).RESULTS: Compared with the lowest quintile, the incidence of invasive breast cancer was reduced in the highest quintile of dietary folate intake (HR: 0.56; 95% CI: 0.35, 0.90; P for trend = 0.02); total folate intake, including supplements (HR: 0.56; 95% CI: 0.34, 0.91; P for trend = 0.006); and dietary folate equivalents (HR: 0.59; 95% CI: 0.36, 0.97; P for trend = 0.01).CONCLUSION: A high folate intake was associated with a lower incidence of postmenopausal breast cancer in this cohort.
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2.
  • Sonestedt, Emily, et al. (författare)
  • Both food habit change in the past and obesity status may influence the association between dietary factors and postmenopausal breast cancer
  • 2007
  • Ingår i: Public Health Nutrition. - 1475-2727. ; 10:8, s. 769-779
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: Valid dietary data are essential when trying to identify whether or not one or more dietary exposures are responsible for disease. We examined diet composition in women who reported dietary change in the past compared with non-changers, and how the associations between dietary factors and postmenopausal breast cancer are influenced by dietary change, obesity status and misreporting of energy. Design: A population-based prospective cohort Study. Data were obtained by a diet history method, anthropometrical measurements and an extensive lifestyle questionnaire including items on past food habit change. Setting: The Malmo Diet and Cancer (MDC) study, conducted in Malmo, Sweden. Subjects: A subsample of 12 781 women from the MDC cohort recruited from 1991 to 1996. A total of 428 postmenopausal women were diagnosed with incident breast cancer, during 9.2 years of follow-up. Results: Past food habit changers reported healthier food habits and lower energy intake compared with non-changers, a finding that raises issues regarding possible reporting biases. When excluding diet changers, the trend of increased breast cancer risk across omega-6 fatty acid quintiles was stronger, and a tendency of decreased risk emerged for 'fruit, berries and vegetables'. When excluding individuals with non-adequate reports of energy intake, risk estimates were similar to that of the whole sample. In women with body mass index < 27kg m(-2) significant trends of increased breast cancer risk were seen for total fat and omega-6 fatty acids, and of decreased risk for 'fruit, berries and vegetables. Conclusions: This study indicates that both obesity and self-reported past food habit change may be important confounders of diet-breast cancer relationships. The study demonstrates that sensitivity analysis, through stratification, may facilitate interpretation of risk relationships and study results.
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  • Resultat 1-2 av 2
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tidskriftsartikel (2)
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refereegranskat (2)
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Wirfält, Elisabet (2)
Sonestedt, Emily (2)
Gullberg, Bo (2)
Olsson, Håkan (1)
Ericson, Ulrika (1)
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Lunds universitet (2)
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Engelska (2)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (2)
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