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- Abdel-Rehim, Mohamed, et al.
(författare)
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Microextraction in Packed Syringe Online with Liquid Chromatography-Tandem Mass Spectrometry : Molecularly imprinted polymer as packing material for MEPS in selective extraction of ropivacaine from plasma
- 2006
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Ingår i: Journal of Liquid Chromatography & Related Technologies. - : Informa UK Limited. - 1082-6076 .- 1520-572X. ; 29:12, s. 1725-1736
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Tidskriftsartikel (refereegranskat)abstract
- The excellent performance of a new sample preparation method, microextraction in packed syringe (MEPS), was recently illustrated by online LC‐MS and GS‐MS assays of local anaesthetics in plasma samples. In the method, approximately 1 mg of solid packing material was inserted into a syringe (100–250 µL) as a plug. Sample preparation took place on the packed bed. The new method was easy to use, fully automated, of low cost, and rapid in comparison with previously used methods. This paper presents the use of molecularly imprinted polymers (MIPs) as packing material for higher extraction selectivity. Development and validation of a method for MIP‐MEPS online with LC‐MS‐MS using ropivacaine in plasma as model compound were investigated. A bupivacaine imprinted polymer was used. The method was validated and the standard curves were evaluated by means of quadratic regression and weighted by inverse of the concentration: 1/x for the calibration range 2–2000 nM. The applied polymer could be used more than 100 times before the syringe was discarded. The extraction recovery was 60%. The results showed high correlation coefficients (R 2 >0.999) for all runs. The accuracy, given as a percentage deviation from the nominal concentration values, ranged from -6% to 3%. The precision, given as the relative standard deviation, at three different concentrations (QC samples) was consistently about 3% to 10%. The limit of quantification was 2 nM.
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- Abraham, Getahun Yacob
(författare)
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Compulsory School Curricula of South Africa (RNCS, 2002) and Sweden (Lpo94).
- 2008
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Ingår i: Compulsory School Curricula of South Africa (RNCS, 2002) and Sweden (Lpo94)..
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Konferensbidrag (refereegranskat)abstract
- Compulsory School Curricula of South Africa (RNCS1, 2002) and Sweden (Lpo 294).AbstractThe aim of this paper is to analyse the compulsory school curricula of South Africa and Sweden. It focuses on contexts for their introduction, main actors in the process, democratic values they contain and their similarities and differences. Norman Fairclough’s Critical Discourse Analysis (CDA) is used for analysis. The curricula and references to other literatures show similarities and differences. Contextual similarities are that both countries were once under oppression and their masses were isolated from the education process and more resources were invested on their elites. At present the curricula of both countries strives for democratic education. A major difference is equal opportunities for the students to attend a school of their choice are higher in Sweden than in South Africa. The Swedish curriculum is more concrete on issues related to students, teachers and other school staff’s rights and responsibilities, and on relations between school, home and society.Key words: South Africa, Sweden, Curricula, and Democratic values
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