| 31. |
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| 32. |
- Jonsson, Anders, et al.
(författare)
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Evaluating a large-scale implementation of Assessment for Learning in Sweden
- 2015
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Ingår i: Assessment in education. - : Routledge. - 0969-594X .- 1465-329X. ; 22:1, s. 104-121
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Tidskriftsartikel (refereegranskat)abstract
- This study reports on a large-scale implementation of Assessment for Learning (AfL) in a Swedish municipality. The implementation was founded on two principles: (1) teaching should be informed by educational research; (2) to be successful teachers' professional development needs to be based in everyday classroom practice. From these principles, AfL was chosen as a strand of educational research to inform teaching and 'Teacher Learning Communities' were chosen as a vehicle for professional development and for implementing AfL practices. Findings indicate that the project has been successful in bringing about a change in how teachers talk about teaching and learning and in changing teachers' pedagogical practice towards AfL. Findings also suggest that AfL practices are mostly teacher-centred, which means that the teachers still take most of the responsibility for the assessment. This leads to high workload for the teachers and may also hinder students from taking responsibility for their learning.
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| 33. |
- Jonsson, Anders, 1966-, et al.
(författare)
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Gas transfer rate and CO2 flux between an unproductive lake and the atmosphere in northern Sweden
- 2008
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Ingår i: Journal of Geophysical Research. - 2156-2202. ; 113, s. Art.no. G04006-
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Tidskriftsartikel (refereegranskat)abstract
- Measurements of the gas transfer rate of CO2 between lake water and the atmosphere present a critical problem for the understanding of lake ecosystem carbon balances and landscape carbon budgets. We present calculations of the gas transfer rate of CO2 from direct measurements of the CO2 flux using an eddy covariance system and concurrent measurements of the concentration of CO2 in the surface water in a lake in boreal zone of northern Sweden. The measured gas transfer rate was different, and in general larger than, rates obtained with the most commonly used models for prediction of the gas transfer rate in lakes. The normalized gas transfer rate (k(600)EC) was well predicted from the wind speed at 10 m height if data were bin classed into wind classes of 1 m/s for winds above 1 m/s. Unbinned data were also correlated to wind speed but also to water temperature, water temperature/air temperature ratio and to incoming photosynthetic active radiation (PAR). These relationships could reflect effects of both physico-chemical reactions and biological activity.
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| 34. |
- Jonsson, Anna-Karin, et al.
(författare)
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A trial with IgY chicken antibodies to eradicate faecal carriage of Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases
- 2015
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Ingår i: Infection Ecology & Epidemiology. - : Informa UK Limited. - 2000-8686 .- 2000-8686. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden, an orphan drug trial on IgY chicken antibodies was undertaken in an attempt to eradicate faecal carriage of ESBL-producing K. pneumoniae and Escherichia coli.METHODS: Hens were immunised with epitopes from freeze-dried, whole-cell bacteria (ESBL-producing K. pneumoniae and E. coli) and recombinant proteins of two K. pneumoniae fimbriae subunits (fimH and mrkD). The egg yolks were processed according to good manufacturing practice and the product was stored at-20°C until used. Using an internal database from the outbreak and the regular laboratory database, faecal carriers were identified and recruited from May 2005 to December 2013. The participants were randomised in a placebo-controlled 1:1 manner.RESULTS: From 749 eligible patients, 327 (44%) had deceased, and only 91 (12%) were recruited and signed the informed consent. In the initial screening performed using the polymerase chain reaction, 24 participants were ESBL positive and subsequently randomised and treated with either the study drug or a placebo. The study was powered for 124 participants. Because of a very high dropout rate, the study was prematurely terminated. From the outbreak cohort (n=247), only eight patients were screened, and only one was positive with the outbreak strain in faeces.CONCLUSIONS: The present study design, using IgY chicken antibodies for the eradication of ESBL-producing K. pneumonia and E. coli, was ineffective in reaching its goal due to high mortality and other factors resulting in a low inclusion rate. Spontaneous eradication of ESBL-producing bacteria was frequently observed in recruited participants, which is consistent with previous reports.
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| 35. |
- Jonsson, Anders, et al.
(författare)
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Limitations of acyclic causal graphs for planning
- 2014
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Ingår i: Artificial Intelligence. - : Elsevier. - 0004-3702 .- 1872-7921. ; 210, s. 36-55
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Tidskriftsartikel (refereegranskat)abstract
- Causal graphs are widely used in planning to capture the internal structure of planning instances. Researchers have paid special attention to the subclass of planning instances with acyclic causal graphs, which in the past have been exploited to generate hierarchical plans, to compute heuristics, and to identify classes of planning instances that are easy to solve. This naturally raises the question of whether planning is easier when the causal graph is acyclic. In this article we show that the answer to this question is no, proving that in the worst case, the problem of plan existence is PSPACE-complete even when the causal graph is acyclic. Since the variables of the planning instances in our reduction are propositional, this result applies to STRIPS planning with negative preconditions. We show that the reduction still holds if we restrict actions to have at most two preconditions. Having established that planning is hard for acyclic causal graphs, we study two subclasses of planning instances with acyclic causal graphs. One such subclass is described by propositional variables that are either irreversible or symmetrically reversible. Another subclass is described by variables with strongly connected domain transition graphs. In both cases, plan existence is bounded away from PSPACE, but in the latter case, the problem of bounded plan existence is hard, implying that optimal planning is significantly harder than satisficing planning for this class.
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| 36. |
- Jonsson, Anders, et al.
(författare)
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When Acyclicity is not Enough: Limitations of the Causal Graph
- 2013
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Ingår i: Proceedings of the Twenty-Third International Conference on Automated Planning and Scheduling. - : AAAI Press. - 9781577356097 ; , s. 117-125
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Konferensbidrag (refereegranskat)abstract
- Causal graphs are widely used in planning to capture the internal structure of planning instances. In the past, causal graphs have been exploited to generate hierarchical plans, to compute heuristics, and to identify classes of planning instances that are easy to solve. It is generally believed that planning is easier when the causal graph is acyclic. In this paper we show that this is not true in the worst case, proving that the problem of plan existence is PSPACE-complete even when the causal graph is acyclic. Since the variables of the planning instances in our reduction are propositional, this result applies to STRIPS planning with negative pre-conditions. Having established that planning is hard for acyclic causal graphs, we study a subclass of planning instances with acyclic causal graphs whose variables have strongly connected domain transition graphs. For this class, we show that plan existence is easy, but that bounded plan existence is hard, implying that optimal planning is significantly harder than satisficing planning for this class.
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| 37. |
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| 38. |
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| 39. |
- Jonsson, Bror, 1948-, et al.
(författare)
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Winter temperature and food quality affect age and size at maturity in ectotherms: an experimentaltest with Atlantic salmon
- 2012
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Ingår i: Canadian Journal of Fisheries and Aquatic Sciences. - : Canada. Dept. of Fisheries and Oceans; National Research Council Canada, National Research Council Canada. - 0706-652X .- 1205-7533. ; 69:11, s. 1817-1826
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Tidskriftsartikel (refereegranskat)abstract
- Field studies have revealed that many ectotherms mature younger and smaller in warmer environments although they grow faster. This has puzzled ecologists because the direct effect of factors that accelerate growth is expected to be larger, not smaller size. We tested this experimentally for Atlantic salmon (Salmo salar) at two winter temperatures and diets. Logistic regression revealed that the probability of maturation during the second year in sea water, relative to the probability of older maturation, increased with temperature and growth rate during the first winter. Also, large size and high condition factor 1 year prior to maturation stimulated maturation. In females, a high lipid diet increased the probability of maturation as one-sea-winter fish, and there were significant interactions between winter temperature and food quality and between body size and condition factor the first autumn in sea water. Thus, if the direct effect of temperature on growth rate is the main effect of warming, salmon are likely to attain maturity younger and smaller. Also, richer food decreased age at maturation in females. This finding has consequences for interpretations of climate change impacts on age at maturity in Atlantic salmon and may also hold for many other ectotherm species.Salmo salar) at two winter temperatures anddiets. Logistic regression revealed that the probability of maturation during the second year in sea water, relative to theprobability of older maturation, increased with temperature and growth rate during the first winter. Also, large size andhigh condition factor 1 year prior to maturation stimulated maturation. In females, a high lipid diet increased the probability ofmaturation as one-sea-winter fish, and there were significant interactions between winter temperature and food quality andbetween body size and condition factor the first autumn in sea water. Thus, if the direct effect of temperature on growth rate isthe main effect of warming, salmon are likely to attain maturity younger and smaller. Also, richer food decreased age atmaturation in females. This finding has consequences for interpretations of climate change impacts on age at maturity in Atlantic salmon and may also hold for many other ectotherm species.
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| 40. |
- Jonsson, Marianne, 1962, et al.
(författare)
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Novel 3D culture system with similarities to the human heart for studies of the cardiac stem cell niche.
- 2010
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Ingår i: Regenerative medicine. - : Future Medicine Ltd. - 1746-076X .- 1746-0751. ; 5:5, s. 725-36
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: The aim of this study was to develop a 3D culture system with similarities to the human heart, which was suitable for studies of adult cardiac stem or progenitor cells. MATERIALS & METHODS: Dissociated cells from human cardiac biopsies were placed in high-density pellet cultures and cultured for up to 6 weeks. Gene and protein expressions, analyzed by quantitative real-time PCR and immunohistochemistry, and morphology were studied in early and late pellets. RESULTS: Cells cultured in the 3D model showed similarities to human cardiac tissue. Moreover, markers for cardiac stem and progenitor cells were also detected after 6 weeks of culture, in addition to markers for signaling pathways active in stem cell niche regulation. CONCLUSIONS: The described 3D culture model could be a valuable tool when studying the influence of different compounds on proliferation and differentiation processes in cardiac stem or progenitor cells in cardiac regenerative research.
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