| 1. |
- Hultin Jäderlund, Karin, et al.
(författare)
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Cerebrospinal Fluid PCR and Antibody Concentrations against Anaplasma phagocytophilum and Borrelia burgdorferi sensu lato in Dogs with Neurological Signs
- 2009
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Ingår i: Journal of Veterinary Internal Medicine. - : Wiley. - 0891-6640 .- 1939-1676. ; 23, s. 669-672
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Tidskriftsartikel (refereegranskat)abstract
- The tick-borne bacteria Borrelia burgdorferi sensu lato (sl) and Anaplasma phagocytophilum have been suspected to cause neurological signs in dogs. Diagnosis often has been made based on positive antibody titers in serum of dogs with neurological signs, but a high seroprevalence in dogs in at-risk populations makes diagnosis difficult.To determine if the neurological signs in dogs examined were caused by any of these bacteria.Fifty-four dogs presented to a board-certified neurologist.Prospective study. We divided dogs into 2 groups: those with inflammatory diseases of the central nervous system (CNS) and those with neurological signs from other diseases. Blood and cerebrospinal fluid (CSF) from all dogs were analyzed.Dogs with inflammatory CNS diseases showed no serum antibodies against any of the agents. Among dogs with neurological signs from other diseases, 10.3% had serum antibodies for B. burgdorferi sl and 20.5% for A. phagocytophilum. All blood samples analyzed for bacterial deoxyribonucleic acid (DNA) and all CSF analyzed for antibodies and bacterial DNA for the 2 agents were negative.Based on this study, these bacteria are unlikely causes of neurologic disease in dogs and the presence of serum antibodies alone does not document or establish a definitive diagnosis of CNS disease caused by these organisms. Dogs that have neurologic disease and corresponding serum antibodies against these agents should have additional tests performed to assess for other potential etiologies of the signs.
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| 2. |
- Jansson Mörk, Marie, et al.
(författare)
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Validation of a national disease recording system for dairy cattle against veterinary practice records
- 2010
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Ingår i: Preventive Veterinary Medicine. - : Elsevier BV. - 0167-5877 .- 1873-1716. ; 93, s. 183-192
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Tidskriftsartikel (refereegranskat)abstract
- In Sweden, morbidity in dairy cattle is monitored through a national disease recording system. This system gives valuable information for research as well as advisory work and genetic evaluation. Our main objective was to evaluate the completeness in the disease recording system.Farm copies of veterinary records (n = 851) from 112 herds, from March 2003 to April 2004, were compared with the information registered in the recording system. The evaluation of completeness was performed at two stages: (i) in the raw data transferred from the Swedish Board of Agriculture (SBA) to the Swedish Dairy Association (for records, cases and diagnostic events) and (ii) in the dairy disease database (DDD) at the Swedish Dairy Association (for diagnostic events). The evaluation was stratified by record type: manual and computerized records from state-employed veterinarians and private veterinarians, respectively.The completeness was high both for records (95-100%) and cases (90-99%) except manual records from private veterinarians (76% for records and 74% for cases). The overall completeness for diagnostic events was 75% in the DDD, with significant differences between record types. For all record types other than manual records from private veterinarians, the majority of diagnostic events lost disappeared after registration in the raw data from the SBA. The reasons for loss found suggest that there is potential for improvement.A multilevel logistic regression analysis showed that the completeness of diagnostic events in the DDD depended on region, diagnosis and veterinary employment. The random effect of veterinarian accounted for 35% of the modeled variation.Future studies are needed to assess how the differential misclassification affect estimates based on the data, and how to account for it. (C) 2009 Elsevier B.V. All rights reserved.
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| 3. |
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| 4. |
- Öhlund, Malin, et al.
(författare)
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Environmental Risk Factors for Diabetes Mellitus in Cats
- 2017
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Ingår i: Journal of Veterinary Internal Medicine. - : WILEY. - 0891-6640 .- 1939-1676. ; 31:1, s. 29-35
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundDiabetes in cats resembles type 2 diabetes in people. The etiology is not fully understood, but both genetic and environmental factors are believed to contribute. ObjectivesTo assess the associations of environmental risk factors with diabetes in cats. AnimalsCats with a diagnosis of diabetes (n = 396) insured by a Swedish insurance company during years 2009-2013, and a control group (n = 1,670) matched on birth year. MethodsA web-based questionnaire was used in a case-control study. An invitation to participate was sent to owners of 1,369 diabetic cats and 5,363 control cats. The survey contained questions related to the cat's breed, age, sex, neutering status, body condition, housing, access to the outdoors, activity level, diet, eating behavior, feeding routine, general health, stressful events, other pets in the household, medications, and vaccination status. Data were analyzed by multiple logistic regression. ResultsResponse rate was 35% for the diabetic group and 32% for the control group. Indoor confinement, being a greedy eater, and being overweight were associated with an increased risk of diabetes. In cats assessed by owners as being normal weight, there was an association between eating predominantly dry food and an increased risk of diabetes (Odds ratio 3.8; 95% confidence intervals 1.3-11.2). Conclusions and Clinical ImportanceDry food is commonly fed to cats worldwide. The association found between dry food and an increased risk of diabetes in cats assessed as normal weight by owners warrants further attention.
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| 5. |
- Öhlund, Malin, et al.
(författare)
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Incidence of Diabetes Mellitus in Insured Swedish Cats in Relation to Age, Breed and Sex
- 2015
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Ingår i: Journal of Veterinary Internal Medicine. - : Wiley. - 0891-6640 .- 1939-1676. ; 29:5, s. 1342-1347
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Tidskriftsartikel (refereegranskat)abstract
- Background: Diabetes mellitus ( DM) is a common endocrinopathy in cats. Most affected cats suffer from a type of diabetes similar to type 2 diabetes in humans. An increasing prevalence has been described in cats, as in humans, related to obesity and other lifestyle factors. Objectives: To describe the incidence of DM in insured Swedish cats and the association of DM with demographic risk factors, such as age, breed and sex. Animals: A cohort of 504,688 individual cats accounting for 1,229,699 cat- years at risk ( CYAR) insured by a Swedish insurance company from 2009 to 2013. Methods: We used reimbursed insurance claims for the diagnosis of DM. Overall incidence rates and incidence rates stratified on year, age, breed, and sex were estimated. Results: The overall incidence rate of DM in the cohort was 11.6 cases ( 95% confidence interval [ CI], 11.0- 12.2) per 10,000 CYAR. Male cats had twice as high incidence rate ( 15.4; 95% CI, 14.4- 16.4) as females ( 7.6; 95% CI, 6.9- 8.3). Domestic cats were at higher risk compared to purebred cats. A significant association with breed was seen, with the Burmese, Russian Blue, Norwegian Forest cat, and Abyssinian breeds at a higher risk compared to other cats. No sex predisposition was found among Burmese cats. Several breeds with a lower risk of DM were identified. Conclusions and clinical importance: Our results verify that the Burmese breed is at increased risk of developing DM. We also identified several previously unreported breeds with increased or decreased risk of DM.
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| 6. |
- Aspán, Anna, et al.
(författare)
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Molecular Evidence for Persistence of Anaplasma phagocytophilum in the Absence of Clinical Abnormalities in Horses after Recovery from Acute Experimental Infection
- 2009
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Ingår i: Journal of Veterinary Internal Medicine. - : Wiley. - 0891-6640 .- 1939-1676. ; 23, s. 636-642
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Tidskriftsartikel (refereegranskat)abstract
- Anaplasma phagocytophilum infects several mammalian species, and can persist in sheep, dogs, and calves. However, whether this organism persists in horses or induces long-term clinical abnormalities is not known.To evaluate whether A. phagocytophilum can persist in horses and to document clinical findings for 3 months after complete recovery from acute disease.Five clinically normal adult horses that had recovered spontaneously from experimentally induced acute disease caused by a Swedish equine isolate of A. phagocytophilum.Horses were monitored for up to 129 days post inoculation (PI) by daily clinical examination and at least alternate day blood sampling for evidence of A. phagocytophilum on polymerase chain reaction (PCR) and blood smears. All horses were euthanized and underwent postmortem examination.All horses were periodically PCR positive after recovery from acute infection. Before day 66 PI 2 horses were persistently PCR negative whereas 3 horses were intermittently PCR positive. Subsequently, 4 of 5 horses were intermittently PCR positive, particularly after stress mimicking interventions. One animal was positive immediately before postmortem examination. Clinical abnormalities related to persistence of anaplasma were not observed. No specific changes were found at postmortem examination, and all sampled tissues from all horses were negative on PCR for A. phagocytophilum.Infection with A. phagocytophilum can persist in the horse for at least 129 days. However, the continued presence of the organism is not associated with detectable clinical or pathological abnormalities.
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| 7. |
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| 8. |
- Byström, Anna, et al.
(författare)
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Influence of girth strap placement and panel flocking material on the saddle pressure pattern during riding of horses
- 2010
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Ingår i: Equine Veterinary Journal. - : Wiley. - 0425-1644 .- 2042-3306. ; 42, s. 502-509
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Tidskriftsartikel (refereegranskat)abstract
- Both flocking material and girthing have a significant influence on the saddle pressure and should thus be considered in saddle fitting. Wool seems a better flocking material than foam of the type used in the current study. For girthing, traditional placement seems equally good if not better than the v-system. However, further studies are needed to show if these results are valid for a larger population of riding horses.
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| 9. |
- Egenvall, Agneta, et al.
(författare)
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Analysis of morbidity and mortality data in riding school horses, with special regard to locomotor problems
- 2009
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Ingår i: Preventive Veterinary Medicine. - : Elsevier BV. - 0167-5877 .- 1873-1716. ; 88, s. 193-204
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Tidskriftsartikel (refereegranskat)abstract
- The incidence of disease, mortality and survival of horses, focusing on locomotor problems, at riding schools were studied, using data from an animal insurance database during 1997-2002. In total 5140 horses from 136 riding schools were included in the analysis. The overall yearly incidence rate (111) was 1584 events of veterinary care per 10,000 horse-years at risk (HYAR). The total and diagnostic mortalities were 790 and 763 deaths per 10,000 HYAR. Rates varied substantially among riding schools. For locomotor problems the rates were 1116 events of veterinary care and 524 deaths per 10,000 HYAR. Multivariable Cox proportional-hazards analysis was performed on horses enrolled in insurance during the study period, including riding schools as frailty effects. For the outcome veterinary care for locomotor problems, the hazard ratios (HR) increased with increasing life-insurance value and Swedish warmbloods and other horses had increased HR compared to ponies. In the model with outcome life claim because of locomotor problems the breed groups Swedish warmblood and other horses also had higher HR than ponies. Age at entry >= 8 years was associated with decreased HR for settled life-insurance cases due to locomotor problems and the two highest categories for insurance value had increased HR compared to the two lower categories. In the model with the outcome life claim because of previously claimed locomotor problems Swedish warmbloods had a higher HR than other horses and ponies. The HR increased by 33% for each year of age at entry. In south-urban areas of Sweden the HR was decreased compared to in all other areas, including baseline. Overall riding schools utilised the insurance more compared to all horses in the insurance database (similar to 22% for the veterinary-care insurance and similar to 79% for the settled life insurance). (C) 2008 Elsevier B.V. All rights reserved.
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| 10. |
- Egenvall, Agneta
(författare)
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Evaluation of dog owners' perceptions concerning radiation therapy
- 2009
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Ingår i: Acta Veterinaria Scandinavica. - : Springer Science and Business Media LLC. - 0044-605X .- 1751-0147. ; 51
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Tidskriftsartikel (refereegranskat)abstract
- Conclusion: The results show that for these owners, RT was a worthwhile treatment modality and that the discomfort for the dog was manageable and acceptable relative to the benefits. Improved continuing education about small animal RT in Sweden will likely result in increased evidence-based and positive treatment recommendations concerning RT by veterinarians.
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