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  • Resultat 11-20 av 101255
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11.
  • A Herrera, I, et al. (författare)
  • Comparing a multi-linear (STEP) and systemic (FRAM) method for accident analysis
  • 2010
  • Ingår i: RELIABILITY ENGINEERING and SYSTEM SAFETY. - London, UK : Elsevier Science B.V., Amsterdam.. - 0951-8320. ; 95:12, s. 1269-1275, s. 19-26
  • Tidskriftsartikel (refereegranskat)abstract
    • Accident models and analysis methods affect what accident investigators look for, which contributory factors are found, and which recommendations are issued. This paper contrasts the Sequentially Timed Events Plotting (STEP) method and the Functional Resonance Analysis Method (FRAM) for accident analysis and modelling. The main issue addressed in this paper is the comparison of the established multi-linear method STEP with the new systemic method FRAM and which new insights the latter provides for accident analysis in comparison to the former established multi-linear method. Since STEP and FRAM are based on a different understandings of the nature of accidents, the comparison of the methods focuses on what we can learn from both methods, how, when, and why to apply them. The main finding is that STEP helps to illustrate what happened, involving which actors at what time, whereas FRAM illustrates the dynamic interactions within socio-technical systems and lets the analyst understand the how and why by describing non-linear dependencies, performance conditions, variability, and their resonance across functions.
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12.
  • A History of the Surrealist Novel
  • 2023. - 1
  • Samlingsverk (redaktörskap) (refereegranskat)abstract
    • A History of the Surrealist Novel offers a rich, long, and elastic historiography of the surrealist novel, taking into consideration an abundance of texts previously left out of critical accounts. Its twenty thematically organized chapters examine surrealist prose texts written in French, English, Spanish, German, Greek, and Japanese, from the emergence of the surrealist movement in the 1920s and 1930s, through the post-war and postmodern periods, and up to the contemporary moment. This approach extends received narratives regarding surrealism's geographical locations and considers its transnational movement and modes of circulation. Moreover, it challenges critical biases that have defined surrealism in predominantly masculine terms, and which tie the movement to the interwar or early post-war years. This book will appeal both to scholars and students of surrealism and its legacies, modernist literature, and the history of the novel.
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13.
  • A Hulten, Maj, et al. (författare)
  • On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model
  • 2010
  • Ingår i: Reproduction. - 1470-1626 .- 1476-3990. ; 139:1, s. 1-9
  • Forskningsöversikt (refereegranskat)abstract
    • We have recently documented that trisomy 21 mosaicism is common in human foetal ovaries. On the basis of this observation we propose that the maternal age effect in Down syndrome (DS) is caused by the differential behaviour of trisomy 21 in relation to disomy 21 oocytes during development from foetal life until ovulation in adulthood. in particular, we suggest that trisomy 21 oocytes, lagging behind those that are disomic, may escape the timed pruning of the seven million in foetal life to the 300-400 finally selected for ovulation. The net effect of this preferential elimination will be an accumulation of trisomy 21 oocytes in the ovarian reserve of older women. We here highlight the implications of this Oocyte Mosaicism Selection (OMS) model with respect to the prevalent view that the maternal age effect is complex, dependent on many different biological and environmental factors. We examine conclusions drawn from recent large-scale studies in families, tracing DNA markers along the length of chromosome 21q between parents and DS children, in comparison to the OMS model. We conclude that these family linkage data are equally compatible with the maternal age effect originating from the accumulation of trisomy 21 oocytes with advancing maternal age. One relatively straightforward way to get to grips with what is actually going on in this regard would be to compare incidence of trisomy 21 oocytes (and their pairing configurations) in foetal ovaries with that in oocytes at the meiosis I stage from adult women.
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14.
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15.
  • A.S.M. Monjurul, Hasan, et al. (författare)
  • Biogas potential from municipal and agricultural residual biomass for power generation in Hazaribagh, Bangladesh : A strategy to improve the energy system
  • 2019
  • Ingår i: Renewable Energy Focus. - : Elsevier BV. - 1755-0084. ; 29:June 2019, s. 14-23
  • Tidskriftsartikel (refereegranskat)abstract
    • Energy is considered as one of the significant benchmarks towards sustainable growth. Due to the recenteconomic growth, energy demand is increasing day by day in Bangladesh. The power generation mainlyrelies on fossil fuels though there are plans to increase the renewable energy share by the concernstakeholders. Considering the global warming, energy generation from renewable sources is consideredas a sustainable way to mitigate the anthropogenic emission. This study, therefore, addresses thepotentiality of biogas production from municipal waste and agricultural residues in a city territory ofDhaka namely Hazaribagh. The potential sources include wastes from two markets, six slaughterhouses,domestic wastes, one poultry farm and three croplands. The calculations made in this study to estimatethe amount of biogas and electricity from the described sources are done in a simple way, just to illustratethe potential. This study suggests that there is a good potentiality of biogas production and electricitygeneration from municipal wastes and agricultural residues of Hazaribagh. Moreover, this study alsomentions the significant actors like government, future owners, people and so on that are needed to beincorporated to implement biogas solution in a city territory.
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16.
  • A. Strumpfer, Johan, et al. (författare)
  • Stretching of Twitchin Kinase
  • 2012
  • Ingår i: Biophysical Journal. - St. Louis, MO, United States : Cell Press. - 0006-3495 .- 1542-0086. ; 102:3 Supplement 1, s. 361a-362a
  • Tidskriftsartikel (refereegranskat)abstract
    • The giant proteins from the titin family, that form cytoskeletal filaments, have emerged as key mechanotransducers in the sarcomere. These proteins contain a conserved kinase region, which is auto-inhibited by a C-terminal tail domain. The inhibitory tail domain occludes the active sites of the kinases, thus preventing ATP from binding. It was proposed that through application of a force, such as that arising during muscle contraction, the inhibitory tail becomes detached, lifting inhibition. The force-sensing ability of titin kinase was demonstrated in AFM experiments and simulations [Puchner, et al., 2008, PNAS:105, 13385], which showed indeed that mechanical forces can remove the autoinhibitory tail of titin kinase. We report here steered molecular dynamics simulations (SMD) of the very recently resolved crystal structure of twitchin kinase, containing the kinase region and flanking fibronectin and immuniglobulin domains, that show a variant mechanism. Despite the significant structural and sequence similarity to titin kinase, the autoinhibitory tail of twitchin kinase remains in place upon stretching, while the N-terminal lobe of the kinase unfolds. The SMD simulations also show that the detachment and stretching of the linker between fibronectin and kinase regions, and the partial extension of the autoinhibitory tail, are the primary force-response. We postulate that this stretched state, where all structural elements are still intact, may represent the physiologically active state.
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17.
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18.
  • Aaboen, Lise (författare)
  • BATON-CHANGING ON EGGSHELLS – TRANSFERRING SUPPLIER RELATIONSHIPS WHEN MOVING PRODUCTION
  • 2014
  • Konferensbidrag (refereegranskat)abstract
    • Production transfers are a result of outsourcing and offshoring decisions. Though, because ofthe strategic focus of the outsourcing literature have not the operational issues of howrelationship development between sender, receiver and raw material been fully depicted. Thepurpose of the present paper is to explore relationship development connected to transfer ofraw material supplies responsibility during transfer of production. To fulfil the purpose, fourdifferent production transfers were studied: three from Sweden to China, Romania andHungary respectively and one transfer from Holland to Sweden. We can see that thedependence and power shifts gradually between the sender and the receiver and therelationship between them sets the arena for what relationship is developed between thereceiver and the raw material suppliers. Furthermore, short social distances can over bridgecultural and technological distances to some extent, because it motivates to take therelationship into a more developed state.
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19.
  • Aaboen, Lise, et al. (författare)
  • Case-based entrepreneurship education in and for the Nordic region
  • 2022
  • Ingår i: Reframing the Case Method in Entrepreneurship Education.. - : Edward Elgar Publishing. - 9781800881143 - 9781800881150 ; , s. 2-17
  • Bokkapitel (refereegranskat)abstract
    • The case method provides entrepreneurship educators with great potential to be entrepreneurial and to think outside the box when adjusting the case method for increased entrepreneurial learning. This chapter provides the theoretical background of case-based entrepreneurship education and a debate on context in case teaching in general and the Nordic countries in particular. Further the chapter provides a synopsis and reflections of how the chapters in this book discuss the design and utilization of cases through 2 parts. Part 1 includes theoretical perspectives, discussions, and practical procedures on how the case method and case activities can be reframed and approached in entrepreneurship education in general and for experiential learning in particular. Part 2 contributes with a collection of Nordic entrepreneurship cases with accompanying teaching notes. We believe that this book is of great inspiration for entrepreneurship educators wanting to use the case method in their teaching.
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20.
  • Aaboen, Lise, et al. (författare)
  • The relationship development aspect of production transfer
  • 2016
  • Ingår i: Journal of Purchasing and Supply Management. - : Pergamon Press. - 1478-4092 .- 1873-6505. ; 22:1, s. 53-65
  • Tidskriftsartikel (refereegranskat)abstract
    • Production transfers are a result of outsourcing and offshoring decisions. Because of the strategic focus of the outsourcing literature, the operational issues of relationship development between sender and receiver and its impact on the transfer progress have not been fully depicted. The purpose of the present paper is to explore relationship development during production transfer. To fulfil this purpose, we studied three different production transfers and derived four propositions for further testing. Our main conclusions included that dependence and power gradually shift between the sender and the receiver and that the relationship between them sets the arena for what types of relationships can be developed between the receiver and the suppliers. Furthermore, short social distances can bridge cultural and technological distances to some extent, because it motivates the actors to bring their relationship into a more developed state. Finally, we noticed that the headquarters’ involvement can work both as an inhibitor as well as a converter.
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