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Sökning: WFRF:(Wennerberg Ann 1955 ) > Göteborgs universitet > (2005-2009)

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1.
  • Sul, Young-Taeg, 1960, et al. (författare)
  • Optimum surface properties of oxidized implants for reinforcement of osseointegration: surface chemistry, oxide thickness, porosity, roughness, and crystal structure
  • 2005
  • Ingår i: International Journal of Oral & Maxillofacial Implants. - Chicago, Ill. : Quintessence Pub. Co.. - 0882-2786 .- 1942-4434. ; 20:3, s. 349-59
  • Tidskriftsartikel (refereegranskat)abstract
    • PURPOSE: To investigate detailed surface characterization of oxidized implants in a newly invented electrolyte system and to determine optimal surface oxide properties to enhance the bone response in rabbits. MATERIALS AND METHODS: A total of 100 screw-type titanium implants were prepared and divided into 1 control group (machine-turned implants) and 4 test groups (magnesium ion-incorporated oxidized implants). Forty implants were used for surface analyses. A total of 60 implants, 12 implants from each group, were placed in the tibiae of 10 New Zealand white rabbits and measured with a removal torque test after a healing period of 6 weeks. RESULTS: For the test groups, the oxide thicknesses ranged from about 1,000 to 5,800 nm; for the control group, mean oxide thickness was about 17 nm. The surface morphology showed porous structures for test groups and nonporous barrier film for the control group. Pore diameter ranged from < or = 0.5 microm to < or = 3.0 microm. In regard to surface roughness, arithmetic average height deviation (Sa) values varied from 0.68 to 0.98 microm for test implants and 0.55 microm for control implants; developed surface ratio (Sdr) values ranged from 10.6% to 46% for the test groups and were about 10.6% for the control group. A mixture of anatase and rutile-type crystals were observed in the test groups; amorphous-type crystals were observed in the control group. After a healing period of 6 weeks, removal torque measurements in all 4 test groups demonstrated significantly greater implant integration as compared to machine-turned control implants (P < or = .033). DISCUSSION: Determinant oxide properties of oxidized implants are discussed in association with bone responses. Of all surface properties, RTVs were linearly increased as relative atomic concentrations of magnesium ion increase. CONCLUSIONS: Surface properties of the oxidized implants in the present study, especially surface chemistry, influenced bone responses. The surface chemistry of the optimal oxidized implant should be composed of approximately 9% magnesium at relative atomic concentration in titanium oxide matrix and have an oxide thickness of approximately 1,000 to 5,000 nm, a porosity of about 24%, and a surface roughness of about 0.8 microm in Sa and 27% to 46% in Sdr; its oxide crystal structure should be a mixture of anatase- and rutile-phase crystals.
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3.
  • Albrektsson, Tomas, 1945, et al. (författare)
  • healing response
  • 2008
  • Ingår i: osseointegration. - : Quintessence Publishing Co, Inc. - 9780867154795 ; , s. 47-50, s. 51-57
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)
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4.
  • Albrektsson, Tomas, 1945, et al. (författare)
  • Oral Implant Surfaces 1
  • 2005
  • Ingår i: Perio & Implant Quarterly 2005. ; 1, s. 33-43
  • Tidskriftsartikel (refereegranskat)
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5.
  • Albrektsson, Tomas, 1945, et al. (författare)
  • Oral Implant Surfaces 11
  • 2005
  • Ingår i: Perio & Implant Quarterly 2005. ; 2, s. 22-49
  • Tidskriftsartikel (refereegranskat)
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7.
  • Albrektsson, Tomas, 1945, et al. (författare)
  • State of the art of oral implants
  • 2008
  • Ingår i: Peridontology 2000. - : Wiley. - 1600-0757 .- 0906-6713. ; 47:1, s. 15-26
  • Tidskriftsartikel (refereegranskat)
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8.
  • Albrektsson, Tomas, 1945, et al. (författare)
  • The impact of oral implants - past and future, 1966-2042
  • 2005
  • Ingår i: J Can Dent Assoc. - 1488-2159. ; 71:5
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper traces the history of oral implants, beginning with their early undocumented use in the mid-1960s. Although early experimentation with the Branemark system of osseointegration was unsuccessful, significant improvements and scrupulous documentation of the 1970s led to their general acceptance. George Zarb spearheaded their introduction into North America and application of the osseointegration technique soon expanded to extraoral craniofacial prostheses and bone-anchored hearing aids.New possibilities, such as altered surface properties and the use of implants in grafted and irradiated bone are currently being explored, although commercial pressure to introduce new products before they are adequately tested is a cause for concern.The future will see bioactive surfaces and additives that stimulate bone growth. In fact, with the possibility of in vivo growth of new teeth, implants may become unnecessary.
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9.
  • Andersson, M., et al. (författare)
  • Using optical tweezers for measuring the interaction forces between human bone cells and implant surfaces: System design and force calibration
  • 2007
  • Ingår i: Rev Sci Instrum. - : AIP Publishing. ; 78:7
  • Tidskriftsartikel (refereegranskat)abstract
    • Optical tweezers were used to study the interaction and attachment of human bone cells to various types of medical implant materials. Ideally, the implant should facilitate cell attachment and promote migration of the progenitor cells in order to decrease the healing time. It is therefore of interest, in a controlled manner, to be able to monitor the cell adhesion process. Results from such studies would help foresee the clinical outcome of integrating medical implants. The interactions between two primary cell culture models, human gingival fibroblasts and bone forming human osteoblast cells, and three different implant materials, glass, titanium, and hydroxyapatite, were studied. A novel type of optical tweezers, which has a newly designed quadrant detector and a powerful 3 W laser was constructed and force calibrated using two different methods: one method in which the stiffness of the optical trap was obtained by monitoring the phase lag between the trap and the moved object when imposing a forced oscillation on the trapped object and another method in which the maximum trapping force was derived from the critical velocity at which the object escapes the trap. Polystyrene beads as well as cells were utilized for the calibrations. This is the first time that cells have been used directly for these types of force calibrations and, hence, direct measurements of forces exerted on cells can be performed, thus avoiding the difficulties often encountered when translating the results obtained from cell measurements to the calibrations obtained with reference materials. This more straightforward approach represents an advantage in comparison to established methods.
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10.
  • Arvidsson, Anna, 1973, et al. (författare)
  • Formation of calcium phosphates on titanium implants with four different bioactive surface preparations. An in vitro study
  • 2007
  • Ingår i: Journal of Materials Science-Materials in Medicine. - : Springer Science and Business Media LLC. - 0957-4530 .- 1573-4838. ; 18:10, s. 1945-1954
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of the present study was to compare the nucleating and growing behaviour on four types of bioactive surfaces by using the simulated body fluid (SBF) model. Titanium discs were blasted and then prepared by alkali and heat treatment, anodic oxidation, fluoridation, or hydroxyapatite coating. The discs were immersed in SBF for 1, 2, 4 and 6 weeks. Calcium phosphates were found on all specimens, as analysed with scanning electron microscopy/energy dispersive X-ray analysis (SEM/EDX). After 1 and 2 weeks of SBF immersion more titanium was accessible with SEM/EDX on the blasted surfaces than the four bioactive surface types, indicating a difference in coverage by calcium phosphates. The Ca/P mean ratio of the surfaces was approximately 1.5 after 1 week, in contrast to the fluoridated specimens which displayed a Ca/P mean ratio of approximately 2. Powder X-ray diffraction (P-XRD) analyses showed the presence of hydroxyapatite on all types of surfaces after 4 and 6 weeks of immersion. The samples immersed for 6 weeks showed a higher degree of crystallinity than the samples immersed for 4 weeks. In conclusion, differences appeared at the early SBF immersion times of 1 and 2 weeks between controls and bioactive surface types, as well as between different bioactive surface types.
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Wennerberg, Ann, 195 ... (48)
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