| 5961. |
- Solander, Tove, 1981-
(författare)
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Signature scents : perfume and characterization in the contemporary novel
- 2010
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Ingår i: The Senses & Society. - Oxford : Berg. - 1745-8927 .- 1745-8935. ; 5:3, s. 301-321
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Tidskriftsartikel (refereegranskat)abstract
- Perfume critique is an underdeveloped academic field and this includes considerations of perfume as a theme within other art forms such as literature. In this article, Angela Carter’s Wise Children and Monika Fagerholm’s Wonderful Women by the Sea are read alongside perfume blogs in order to analyze the significance of perfume references in the novels. It is demonstrated that the authors’ choice of perfumes for their characters plays a crucial part in their characterization, especially in relation to the theme of identity change. Using Alfred Gell’s analysis of perfume use as bound up with “the transcendence of the sweet life,” it is argued that female characters use perfume to become someone else, sometimes a past self. Furthermore, the use of perfume as a literary device in these novels is shown serve as the vehicle for a feminist critique of the division between “masculine” “high” and “feminine” “low” culture.
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| 5962. |
- Solberg, Arne, et al.
(författare)
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Residual Prostate Cancer in Patients Treated with Endocrine Therapy with or Without Radical Radiotherapy : A Side Study of the SPCG-7 Randomized Trial.
- 2011
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Ingår i: International journal of radiation oncology, biology, physics. - : Elsevier. - 1879-355X .- 0360-3016. ; 80:1, s. 55-61
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: The Scandinavian Prostate Cancer Group-7 randomized trial demonstrated a survival benefit of combined endocrine therapy and external-beam radiotherapy over endocrine therapy alone in patients with high-risk prostate cancer. In a subset of the study population, the incidence and clinical implications of residual prostate cancer in posttreatment prostate biopsy specimens was evaluated. METHODS AND MATERIALS: Biopsy specimens were obtained from 120 of 875 men in the Scandinavian Prostate Cancer Group-7 study. RESULTS: Biopsies were performed at median of 45 months follow-up. In 63 patients receiving endocrine treatment only and 57 patients receiving combined treatment, residual cancer was found in 66% (n = 41) and 22% (n = 12), respectively (p < 0.0001). The vast majority of residual tumors were poorly differentiated (Gleason score >/=8). Endocrine therapy alone was predictive of residual prostate cancer: odds ratio 7.49 (3.18-17.7), p < 0.0001. In patients with positive vs. negative biopsy the incidences of clinical events were as follows: biochemical recurrence 74% vs. 27% (p < 0.0001), local progression 26% vs. 4.7% (p = 0.002), distant recurrence 17% vs. 9.4% (p = 0.27), clinical recurrence 36% vs. 13% (p = 0.006), cancer-specific death 19% vs. 9.7% (p = 0.025). In multivariable analysis, biochemical recurrence was significantly associated with residual cancer: hazard ratio 2.69 (1.45-4.99), p = 0.002, and endocrine therapy alone hazard ratio 3.45 (1.80-6.62), p < 0.0001. CONCLUSIONS: Radiotherapy combined with hormones improved local tumor control in comparison with endocrine therapy alone. Residual prostate cancer was significantly associated with serum prostate-specific antigen recurrence, local tumor progression, clinical recurrence, and cancer-specific death in univariable analysis. Residual cancer was predictive of prostate-specific antigen recurrence in multivariable analysis.
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| 5963. |
- Solberg, Arne, et al.
(författare)
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Side-effects of post-treatment biopsies in prostate cancer patients treated with endocrine therapy alone or combined with radical radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial
- 2011
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Ingår i: Scandinavian Journal of Urology and Nephrology. - : Informa UK Limited. - 0036-5599 .- 1651-2065. ; 45:4, s. 233-238
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Tidskriftsartikel (refereegranskat)abstract
- Objective. Post-treatment prostate biopsy side-effects were evaluated in patients with locally advanced prostate cancer on endocrine therapy alone or combined with radiotherapy in the Scandinavian Prostate Cancer Group-7 randomized trial. Material and methods. One-hundred and twenty patients underwent transrectalultrasound-guided biopsy, and were requested to complete a questionnaire on side-effects occurring within 7 days' follow-up. Results. The questionnaire was returned by 109 patients (91%) (endocrine therapy only 52%, combined endocrine therapy and radiotherapy 48%). Previous therapy had no significant influence on pain, urinary flow, haematuria or haematospermia. Pain at biopsy was reported in 63% (mild, 57%; moderate, 5.6%; severe, one patient) and pain at follow-up in 31% (mild, 27%; moderate, four patients). Haematuria (mean duration 2.2 days) was reported in 41%, and reduced urinary flow in 20% (mild, 18%; severe: four patients; no patient had urinary retention). Haematospermia was scarce. No patient reported urinary tract infection. Rectal bleeding occurred in 18% in the endocrine and 35% in the combined therapy group (p = 0.047), with a mean duration of 1.6 and 2.2 days, respectively (p = 0.031). In logistic regression analysis, a trend towards increased rectal bleeding was found in patients on combined endocrine therapy and radiotherapy (odds ratio 2.4, p = 0.050). Conclusion. Patient-reported post-treatment prostate biopsy side-effects were mild and self-limiting.
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| 5964. |
- Soloviev, A. A., et al.
(författare)
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Fast electron generation using PW-class PEARL facility
- 2011
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Saunders Elsevier. - 0168-9002 .- 1872-9576. ; 653:1, s. 35-41
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Tidskriftsartikel (refereegranskat)abstract
- We use a PW-class PEARL facility to study fast electron beam generation during high intensity laser pulse interaction with a supersonic gas jet. We show that electron beams with several hundreds of MeV and relatively large charges, of hundreds of pC and more, can be effectively produced without any guiding structures. PIC simulations also confirm the obtained experimental data and provide optimized conditions of laser–plasma interaction for high-charged beam production.
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| 5965. |
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| 5966. |
- Song, Tianyan, et al.
(författare)
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VrrA mediates Hfq-dependent regulation of OmpT synthesis in Vibrio cholerae
- 2010
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Ingår i: Journal of Molecular Biology. - : Elsevier BV. - 0022-2836 .- 1089-8638. ; 400:4, s. 682-688
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Tidskriftsartikel (refereegranskat)abstract
- OmpT, an outer membrane porin of Vibrio cholerae, is tightly regulated by the organism in response to different environments. Two transcriptional regulators, cAMP receptor protein (CRP) and ToxR, compete at the ompT promoter region. CRP activates ompT transcription by a loop-forming mechanism, while ToxR functions as an antiactivator and repressor, depending on its interplay with CRP. VrrA, a 140-nt small noncoding RNA in V. cholerae, is controlled by the alternative sigma factor sigma(E). We have demonstrated previously that VrrA represses ompA translation by base-pairing with the 5’ region of the mRNA, thereby affecting the release of outer membrane vesicles and modulating the colonization ability of V. cholerae. In this study, we demonstrate that VrrA RNA represses ompT translation by base-pairing with the 5’ region of the mRNA and that regulation requires the RNA chaperone protein Hfq. These results add new insight into the regulation of OmpT. In addition to pH/temperature signals via the ToxR regulon and carbon source signals via the cAMP-CRP complex, OmpT is further regulated by signals received via the sigma(E) regulon through VrrA.
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| 5967. |
- Song, Xiaowei, et al.
(författare)
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Surface Hydroxyl Identity and Reactivity in Akaganeite
- 2011
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Ingår i: The Journal of Physical Chemistry C. - Washington DC : American Chemical Society. - 1932-7447 .- 1932-7455. ; 115:34, s. 17036-17045
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Tidskriftsartikel (refereegranskat)abstract
- Hydroxyl groups on surfaces of well-defined akaganeite (beta-FeOOH) particles were identified by Fourier transform infrared spectroscopy. These efforts, assisted by molecular dynamics simulations, enabled the extraction of spectral signatures for these groups of the dominant (100), (001), and (010) crystallographic planes. Band assignments were supported by spectral variations induced by proton and chloride adsorption as well as temperature-programmed desorption. Molecular dynamics simulations were used to determine patterns and free energies of formation of hydrogen bonds. Surface Fe-O distances as well as hydrogen-bond numbers were also used to predict proton affinities. All spectral component concentrations display highly comparable responses to proton loadings with those of other FeOOH minerals previously studied with our coupled experimental-theoretical approach. These similarities underpin common thermodynamic stabilities for hydroxyls of a given Fe nuclearity on different planes of different minerals.
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| 5968. |
- Song, Yi, et al.
(författare)
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Broadband coupler between silicon waveguide and hybrid plasmonic waveguide
- 2010
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Ingår i: Optics Express. - : Optical Society of America. - 1094-4087. ; 18:12
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Tidskriftsartikel (refereegranskat)abstract
- Efficient broadband coupling of light between a dielectric waveguide and a hybrid plasmonic waveguide is investigated theoretically. A plasmonic linear taper is used as a coupler which connects the two types of waveguides. Broadband coupling is realized by such a compact plasmonic taper with a length of only 0.4μm, which achieves a coupling efficiency of 70% (1.5dB) at the 1.55μm telecommunication wavelength.
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| 5969. |
- Song, Yi, et al.
(författare)
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Efficient coupling between dielectric and hybrid plasmonic waveguides by multimode interference power splitter
- 2011
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Ingår i: Journal of optics. - : IOP Publishing. - 0150-536X .- 2040-8978 .- 2040-8986. ; 13:7, s. 075002-
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Tidskriftsartikel (refereegranskat)abstract
- Multimode interference power splitters based on hybrid plasmonic waveguides are investigated theoretically. Balanced power splitting is achieved in designed 1 × 3 and 1 × 2 power splitters between a silicon-on-insulator waveguide and several hybrid plasmonic waveguides, with total transmission efficiencies at 76.1% and 78.3% at the wavelength of 1550 nm, respectively.
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| 5970. |
- Song, Yi, et al.
(författare)
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Reducing crosstalk between nanowire-based hybrid plasmonic waveguides
- 2011
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Ingår i: Optics Communications. - : Elsevier BV. - 0030-4018 .- 1873-0310. ; 284:1, s. 480-484
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Tidskriftsartikel (refereegranskat)abstract
- Hybrid plasmonic waveguides based on a surface oxidized dielectric nanowire placed on a metal surface can facilitate simultaneously deep subwavelength mode confinement and large propagation length. Directional coupling based on such waveguides are theoretically investigated. Much lower crosstalk is noticed for such hybrid plasmonic waveguides compared to conventional waveguides based on bare dielectric nanowires. Some modifications, such as vertically placing the metal surfaces or using a metallic block between the nanowires, are studied which can further reduce the crosstalk between two waveguides. The proposed low crosstalk structures based on hybrid plasmonic waveguides can provide a simple platform for plasmonic integration which can at the same time easily interface with traditional photonic circuits. (C) 2010 Elsevier B.V. All rights reserved.
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