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Sökning: LAR1:his

  • Resultat 3231-3240 av 7537
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3231.
  • Jansson, Hanna, 1975, et al. (författare)
  • The crystal structure of the spinach plastocyanin double mutant G8D/L12E gives insight into its low reactivity towards photosystem 1 and cytochrome f
  • 2003
  • Ingår i: Biochimica et Biophysica Acta. - : Elsevier BV. - 0005-2728 .- 1879-2650. ; 1607:2-3, s. 203-210
  • Tidskriftsartikel (refereegranskat)abstract
    • Plastocyanin (Pc) is a copper-containing protein, which functions as an electron carrier between the cytochrome b6f and photosystem 1 (PS1) complexes in the photosynthetic electron transfer (ET) chain. The ET is mediated by His87 situated in the hydrophobic surface in the north region of Pc. Also situated in this region is Leu12, which mutated to other amino acids severely disturbs the ET from cytochrome f and to PS1, indicating the importance of the hydrophobic surface. The crystal structure of the Pc double mutant G8D/L12E has been determined to 2.0 Å resolution, with a crystallographic R-factor of 18.3% (Rfree=23.2%). A comparison with the wild-type structure reveals that structural differences are limited to the sites of the mutations. In particular, there is a small but significant change in the hydrophobic surface close to His87. Evidently, this leads to a mismatch in the reactive complex with the redox partners. For PS1 this results in a 20 times weaker binding and an eightfold slower ET as determined by kinetic measurements. The mutations that have been introduced do not affect the optical absorption spectrum. However, there is a small change in the EPR spectrum, which can be related to changes in the copper coordination geometry.
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3232.
  • Jansson, Inger, et al. (författare)
  • Beyond conventional healthcare for mental health problems : Experiences of existential group conversations
  • 2023
  • Ingår i: Scandinavian Journal of Occupational Therapy. - : Taylor & Francis Group. - 1103-8128 .- 1651-2014. ; 31:1
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundMental health problems (MHP) are a major public health challenge. Conventional healthcare has shown limitation on reducing MHP and there is a call for offering methods beyond healthcare as well as improve access to healthcare.AimsTo explore experiences among people having MHP of (i) taking part in existential conversations in groups beyond conventional healthcare and (ii) seeking and receiving conventional healthcare.Materials and methodsFour focus group interviews were conducted after finishing existential conversations in groups. Data was analyzed following thematic analysis.ResultsThe theme Access to a community for exploration and acceptance describes communication through impressions and expressions together with others. A reflective perspective on everyday life, describes re-evaluation through reflection. Within the theme Experiences of healthcare related encounters, referring to the second aim, participants recollected feelings of disconnectedness, difficulties verbalizing MHP and dealing with rigid, standardized measures.ConclusionExistential conversations in group may contribute to a more reflected doing in accordance with one’s own values as well as improved mental health literacy. Design and measures within healthcare need to explicitly address MHP and consider individual’s own preferences.SignificanceThis study contributes to understanding of coping with MHP in everyday life from an existential perspective.
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3233.
  • Jansson, Johan, et al. (författare)
  • An anisotropic non-linear material model for glass fibre reinforced plastics
  • 2018
  • Ingår i: Composite structures. - : Elsevier. - 0263-8223 .- 1879-1085. ; 195, s. 93-98
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper aims to present a methodology to predict the anisotropic and non-linear behaviour of glass fibre reinforced plastics using finite element methods. A material model is implemented in order to remedy the need of multiple material definitions, and to control the local plastic behaviour as a function of the fibre orientation. Injection moulding simulations traditionally provide second order orientation tensors, which are considered together with a homogenization scheme to compute local material properties. However, in the present study, fourth order tensors are used in combination with traditional methods to provide more accurate material properties. The elastic and plastic response of the material model is optimized to fit experimental test data, until simulations and experiments overlap. The proposed material model can support design engineers in making more informed decisions, allowing them to create smarter products without the need of excessive safety factors, leading to reduced component weight and environmental impact. 
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3234.
  • Jansson, Johan, et al. (författare)
  • Image-based semi-multiscale finite element analysis using elastic subdomain homogenization
  • 2021
  • Ingår i: Meccanica (Milano. Print). - : Springer. - 0025-6455 .- 1572-9648. ; 56:11, s. 2799-2811
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper we present a semi-multiscale methodology, where a micrograph is split into multiple independent numerical model subdomains. The purpose of this approach is to enable a controlled reduction in model fidelity at the microscale, while providing more detailed material data for component level- or more advanced finite element models. The effective anisotropic elastic properties of each subdomain are computed using periodic boundary conditions, and are subsequently mapped back to a reduced mesh of the original micrograph. Alternatively, effective isotropic properties are generated using a semi-analytical method, based on averaged Hashin–Shtrikman bounds with fractions determined via pixel summation. The chosen discretization strategy (pixelwise or partially smoothed) is shown to introduce an uncertainty in effective properties lower than 2% for the edge-case of a finite plate containing a circular hole. The methodology is applied to a aluminium alloy micrograph. It is shown that the number of elements in the aluminium model can be reduced by 99.89 % while not deviating from the reference model effective material properties by more than 0.65 % , while also retaining some of the characteristics of the stress-field. The computational time of the semi-analytical method is shown to be several orders of magnitude lower than the numerical one. © 2021, The Author(s).
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3235.
  • Jansson, Johan, et al. (författare)
  • On the use of heterogeneous thermomechanical and thermophysical material properties in finite element analyses of cast components
  • 2019
  • Ingår i: Joint 5th International Conference on Advances in Solidification Processes (ICASP-5) & 5th International Symposium on Cutting Edge of Computer Simulation of Solidification, Casting and Refining (CSSCR-5) 17–21 June 2019, Salzburg, Austria. - : Institute of Physics Publishing (IOPP).
  • Konferensbidrag (refereegranskat)abstract
    • Cast components generally show a heterogeneous distribution of material properties, caused by variations in the microstructure that forms during solidification. Variations caused by the casting process are not commonly considered in structural analyses, which might result in manufacturing of sub-optimised components with unexpected in-use behaviour. In this paper, we present a methodology which can be used to consider both thermomechanical and thermophysical variations using finite element analyses in cast components. The methodology is based on process simulations including microstructure modelling and correlations between microstructural features and material properties. Local material data are generated from the process simulation results, which are integrated into subsequent structural analyses. In order to demonstrate the methodology, it is applied to a cast iron cylinder head. The heterogeneous distribution of material properties in this component is investigated using experimental methods, demonstrating local variations in both mechanical and physical behaviour. In addition, the strength-differential effect on tensile and compressive behaviour of cast iron is considered in the modelling. The integrated simulation methodology presented in this work is relevant to both design engineers, production engineers as well as material scientists, in order to study and better understand how local variations in microstructure might influence the performance and behaviour of cast components under in-use conditions.
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3236.
  • Jansson, Johan, et al. (författare)
  • Simulation-driven product development of cast components with allowance for process-induced material behaviour
  • 2020
  • Ingår i: Journal of Computational Design and Engineering. - : Oxford University Press. - 2288-5048. ; 7:1, s. 78-85
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper presents a methodology that can be used to consider local variations in thermomechanical and thermophysical material properties, residual stresses, and strength-differential effects in finite element analyses of cast components. The methodology is based on applying process simulations and structural analyses together with experimentally established, or already available literature data, in order to describe element-specific material variations. A cast-iron cylinder head was used in order to evaluate the influence of several simplifications that are commonly performed in computer aided engineering. It is shown that non-trivial errors of a potentially large magnitude are introduced by not considering residual stresses, compressive behaviour, temperature dependence, and process-induced material property variations. By providing design engineers with tools that allow them to consider the complex relationships between these aspects early in the development phase, cast components have the potential to be further optimized with respect to both weight and performance.
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3237.
  • Jansson, Magnus, et al. (författare)
  • Banks' risk taking in credit decisions : influences of loan officers' personality traits and financial risk preference versus bank-contextual factors
  • 2023
  • Ingår i: Managerial Finance. - : Emerald Group Publishing Limited. - 0307-4358 .- 1758-7743. ; 49:8, s. 1297-1313
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: This paper aims to investigate whether loan officers' risk taking in credit decisions are associated with their personal financial risk preference and personality traits or solely with bank-contextual and loan-relevant factors. Design/methodology/approach: An online survey administered in six large Swedish banks to 163 loan officers responsible for assessing credit risk and approval of loan applications. The loan officers rated their likelihood of approving fictitious loan applications from business companies. Findings: The loan officers' credit risk taking is associated with bank-contextual factors, directly with perceived organizational credit risk norms and indirectly with self-confidence in assessing credit risks through attitude to credit risk taking. A direct association is also found with personal financial risk preference but not with personality traits. Research limitations/implications: Increased awareness of that loan officers' personal financial risk preference is associated with their credit risk taking in loan decisions but that the banks' risk policy has a stronger association. Banks' managements and boards should therefore assure that their credit risk policy is implemented, followed and being aligned with their performance incentives. Practical implications: Increased awareness of that loan officers' credit risk taking is associated with personal financial risk preference but more strongly with the banks' risk policy that motivate banks' managements and boards to assure that their credit risk policy is implemented, followed and being aligned with their performance incentives. Originality/value: The first study which directly compare the associations of loan officers' risk taking in credit approvals with personal risk preference and personality traits versus bank-contextual factors and loan-relevant information. 
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3238.
  • Jansson, Magnus, et al. (författare)
  • Drivers of outsourcing and backsourcing in the public sector : From idealism to pragmatism
  • 2020
  • Ingår i: Financial Accountability and Management. - : John Wiley & Sons. - 0267-4424 .- 1468-0408. ; 37:3, s. 262-278
  • Tidskriftsartikel (refereegranskat)abstract
    • Local governments are bringing previously outsourced services back in-house. Research into explanations for sourcing decisions in the public sector is growing, however, few researchers have investigated drivers of both outsourcing and backsourcing in local public-governance organizations. In this study we utilize transaction cost economic theory (TCE) and political ideology to investigate underlying motives of sourcing in local public governance organizations. Based on a 2018 survey of chief financial officers (CEO) in all of Sweden's 290 municipalities, this study shows that backsourcing is strongly associated with outsourcing and that outsourcing and backsourcing should not be understood as opposite phenomena, rather as interdependent phenomena in a dynamic sourcing strategy. Outsourcing and backsourcing are driven in part by different factors: Outsourcing by political ambitions and economic factors relating to TCE, while managerial and pragmatic concerns are foregrounded for backsourcing.
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3239.
  • Jansson, Magnus, et al. (författare)
  • Non-professional versus professional investors’ trust in financial analysts’ recommendations and influences on investments
  • 2024
  • Ingår i: Review of Behavioral Finance. - : Emerald Group Publishing Limited. - 1940-5979 .- 1940-5987. ; 16:5, s. 860-882
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: The paper aims to investigate differences in non-professional and professional stock investors’ trust in and tendency to follow financial analysts’ buy and sell recommendations. Design/methodology/approach: Online experiment conducted in Sweden in March 2022 comparing non-professional private investors (n = 80), professional investors (n = 33), and master students in finance (n = 28). Information was presented about four company stocks listed on the New York stock exchange. Two stocks were buy-recommended and two stocks sell-recommended by financial analysts. For one stock of each type, the recommendation was presented to participants. Dependent variables were predictions of the stock price after three months, ratings of confidence in the predictions and choices of holding, buying or selling the stock. Ratings were also made of the importance of presented stock-related information as well as trust in analysts’ skill and integrity. Findings: More positive return predictions were made of buy-recommended than sell-recommended stocks. Non-professionals and to some degree finance students tended to trust financial analysts more than professional investors did and they were more influenced by the presentation of the buy recommendations. All groups made too optimistic return predictions, but the professionals were less confident in their predictions, more likely to sell the stocks and lost less on their investments. Originality/value: A new finding is that non-professional stock investors are more likely than professional stock investors to trust financial analysts and follow their recommendations. It suggests that financial analysts’ recommendations influence non-professional investors to take unmotivated investment risks. Non-professionals in the stock market should hence be advised to exercise more caution in following analysts’ recommendations. 
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3240.
  • Jansson, Magnus, et al. (författare)
  • Outsourcing and backsourcing in a time of crisis – experiences of double opportunism
  • 2024
  • Ingår i: International Review of Public Administration. - : Taylor & Francis Group. - 1229-4659 .- 2331-7795. ; 29:2, s. 102-122
  • Tidskriftsartikel (refereegranskat)abstract
    • This article addresses the question of how public organizations with limited capacity manage to handle large scale crises. The case analyzed in this article is the sourcing of accommodation during the migration crisis in Sweden of 2015–2016. The event was a game-changer in Swedish migration policy following a more hesitant policy than before, even though new and substantial migration crisis have followed since then. Results show how the legal framework for procurements was not adapted for extraordinary events. The Swedish state was forced to pay exaggerated prices as private contractors took advantage of the acute demand. The study develops our theoretical understanding of the sourcing process during crises and show how the short-term perspective and uncertainties that characterize crises encourage both suppliers and procurers of services to act opportunistically. 
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