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Sökning: LAR1:lu > Chalmers tekniska högskola > Konferensbidrag > (2010-2013) > Naturvetenskap

  • Resultat 1-10 av 12
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1.
  • Berntsson Svensson, Richard, et al. (författare)
  • Prioritization of quality requirements : State of practice in eleven companies
  • 2011
  • Ingår i: 2011 IEEE 19th International Requirements Engineering Conference, RE 2011; Trento; 29 August 2011 through 2 September 2011. - Trento : IEEE. - 9781457709234 ; , s. 69-78, s. 69-78
  • Konferensbidrag (refereegranskat)abstract
    • Requirements prioritization is recognized as an important but challenging activity in software product development. For a product to be successful, it is crucial to find the right balance among competing quality requirements. Although literature offers many methods for requirements prioritization, the research on prioritization of quality requirements is limited. This study identifies how quality requirements are prioritized in practice at 11 successful companies developing software intensive systems. We found that ad-hoc prioritization and priority grouping of requirements are the dominant methods for prioritizing quality requirements. The results also show that it is common to use customer input as criteria for prioritization but absence of any criteria was also common. The results suggests that quality requirements by default have a lower priority than functional requirements, and that they only get attention in the prioritizing process if decision-makers are dedicated to invest specific time and resources on QR prioritization. The results of this study may help future research on quality requirements to focus investigations on industry-relevant issues.
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2.
  • Fritzsche, Joachim, 1977, et al. (författare)
  • A lipid-based passivation scheme for nanofluidics
  • 2012
  • Ingår i: 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012; Okinawa; Japan; 28 October 2012 through 1 November 2012. - 9780979806452 ; , s. 1876-1878
  • Konferensbidrag (refereegranskat)abstract
    • Stretching DNA in nanochannels allows for direct, visual studies of genomic DNA at the single molecule level. In order to facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We show long-term passivation of nanochannel surfaces to several relevant reagents and demonstrate that the performance of the lipid bilayer is significantly better compared to standard bovine serum albumin-based passivation. Moreover, we demonstrate how the passivated devices allow us to monitor single DNA cleavage events during enzymatic degradation.
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3.
  • Emilsson, Gustav, 1989, et al. (författare)
  • Identifying bacteria using DNA binding maps
  • 2013
  • Ingår i: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. - 9781632666246 ; 1, s. 473-475
  • Konferensbidrag (refereegranskat)abstract
    • We have developed an assay, based on nanofluidic channels and fluorescence microscopy, for optical mapping of DNA based on competitive binding between two molecules - one fluorescent and one sequence selective. From the experimental data we can extract binding constants for the two competing DNA binders, which may be subsequently used to calculate a theoretical reference map of any DNA with known sequence. The goal is to create a method for fast identification of bacteria from single DNA molecules without the need for additional cultivation or amplification. We here demonstrate a proof-of-principle experiment on phage DNA and furthermore show that the method can be used to distinguish between two strains of E. coli DNA and to map pieces of DNA onto the full genome.
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4.
  • Strandmark, Petter, et al. (författare)
  • Shortest Paths with Curvature and Torsion
  • 2013
  • Ingår i: Computer Vision (ICCV), 2013 IEEE International Conference on. - 1550-5499. - 9781479928392 ; , s. 2024-2031
  • Konferensbidrag (refereegranskat)abstract
    • This paper describes a method of finding thin, elongated structures in images and volumes. We use shortest paths to minimize very general functionals of higher-order curve properties, such as curvature and torsion. Our globally optimal method uses line graphs and its runtime is polynomial in the size of the discretization, often in the order of seconds on a single computer. To our knowledge, we are the first to perform experiments in three dimensions with curvature and torsion regularization. The largest graphs we process have almost one hundred billion arcs. Experiments on medical images and in multi-view reconstruction show the significance and practical usefulness of regularization based on curvature while torsion is still only tractable for small-scale problems
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5.
  • Westerlund, Fredrik, 1978, et al. (författare)
  • Fluorescence enhancement from single DNA molecules confined in SiO 2 nanochannels
  • 2010
  • Ingår i: 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Groningen; Netherlands; 3 October 2010 through 7 October 2010. - 9781618390622
  • Konferensbidrag (refereegranskat)abstract
    • We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nanofunnels changes significantly and not monotonically with the width of the funnel, an emission enhancement that is only detected for emitted light polarized parallel to the channel. We explain the enhancement effect as being due to optical phenomena in the channels. The enhancement effect may be of importance for quantitative fluorescence microscopy and for experiments with a tight photon budget.
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6.
  • Beech, J. P., et al. (författare)
  • What do photons do to fluorescently stained DNA in confinement?
  • 2013
  • Ingår i: 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Freiburg; Germany; 27 October 2013 through 31 October 2013. ; 1, s. 5-7
  • Konferensbidrag (refereegranskat)abstract
    • We have studied a selection of factors influencing the damage of DNA in nanochannels during fluorescence imaging. For cutting and nicking of DNA we show that the DNA is shortened during imaging. To avoid photodamage over the course of several hours of a typical experiment, we demonstrate the importance of an oxygen free gas to propel the buffer solution through the device. Finally, by varying the size of the channels, we show indications that higher DNA concentrations lead to higher rates of photodamage necessitating a balance between needs for highly stretched DNA and needs for long measurement times.
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7.
  • Borin, Lars, 1957, et al. (författare)
  • Mining semantics for culturomics: towards a knowledge-based approach
  • 2013
  • Ingår i: 2013 ACM International Workshop on Mining Unstructured Big Data Using Natural Language Processing, UnstructureNLP 2013, Held at 22nd ACM International Conference on Information and Knowledge Management, CIKM 2013; San Francisco, CA; United States; 28 October 2013 through 28 October 2013. - New York, NY, USA : ACM. - 9781450324151 ; , s. 3-10
  • Konferensbidrag (refereegranskat)abstract
    • The massive amounts of text data made available through the Google Books digitization project have inspired a new field of big-data textual research. Named culturomics, this field has attracted the attention of a growing number of scholars over recent years. However, initial studies based on these data have been criticized for not referring to relevant work in linguistics and language technology. This paper provides some ideas, thoughts and first steps towards a new culturomics initiative, based this time on Swedish data, which pursues a more knowledge-based approach than previous work in this emerging field. The amount of new Swedish text produced daily and older texts being digitized in cultural heritage projects grows at an accelerating rate. These volumes of text being available in digital form have grown far beyond the capacity of human readers, leaving automated semantic processing of the texts as the only realistic option for accessing and using the information contained in them. The aim of our recently initiated research program is to advance the state of the art in language technology resources and methods for semantic processing of Big Swedish text and focus on the theoretical and methodological advancement of the state of the art in extracting and correlating information from large volumes of Swedish text using a combination of knowledge-based and statistical methods.
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8.
  • Engström, Emelie, et al. (författare)
  • Indirect effects in evidential assessment: A case study on regression test technology adoption
  • 2012
  • Ingår i: 2nd International Workshop on Evidential Assessment of Software Technologies, EAST 2012. Lund, 22 September 2012. - New York, NY, USA : ACM. - 9781450315098 ; , s. 15-20
  • Konferensbidrag (refereegranskat)abstract
    • Background: There is a need for effcient regression testing in most software development organizations. Often the proposed solutions involve automation. However, despite this being a well researched area, research results are rarely applied in industrial practice. Aim: In this paper we aim to bridge the gap between research and practice by providing examples of how evidence-based regression testing approaches can be adopted in industry. We also discuss challenges for the research community. Method: An industrial case study was carried out to evaluate the possibility to improve regression testing at Sony Ericsson Mobile Communications. We analyse the procedure undertaken based on frameworks from the evidence based software engineering, EBSE, paradigm (with a focus on the evidence) and automation literature (with a focus on the practical effects). Results: Our results pinpoint the need for systematic approaches when introducing a new tool. Practitioners and researchers need congruent guidelines supporting the appraisal of both the evidence base and the pragmatic effects, both direct but also indirect, of the changes. This is illustrated by the introduction of the automation perspective.
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9.
  • Strannegård, Claes, 1962, et al. (författare)
  • Transparent Neural Networks: Integrating Concept Formation and Reasoning
  • 2012
  • Ingår i: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). - Berlin, Heidelberg : Springer Berlin Heidelberg. - 1611-3349 .- 0302-9743. - 9783642355059 - 9783642355066 ; 7716, s. 302-311
  • Konferensbidrag (refereegranskat)abstract
    • We present the transparent neural networks, a graph-basedcomputational model that was designed with the aim of facilitating humanunderstanding. We also give an algorithm for developing such networksautomatically by interacting with the environment. This is doneby adding and removing structures for spatial and temporal memory.Thus we automatically obtain a monolithic computational model whichintegrates concept formation with deductive, inductive, and abductivereasoning.
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10.
  • Coldrey, Mikael, 1972, et al. (författare)
  • Higher order MIMO outdoor-to-indoor measurements using repeaters
  • 2010
  • Ingår i: IEEE Vehicular Technology Conference. - 1550-2252. - 9781424425198
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • In this paper we present results from a outdoor- to-indoor MIMO measurement campaign where we study the effect of repeaters on singular values, spatial richness, capacity, and delay spread distributions. We present results from different repeater scenarios such as, e.g. different outdoor/indoor repeater deployments with single/dual polarized antennas. The measurements show that repeaters significantly enhance the received SNR while they increase the delay spread and decrease the spatial richness of the MIMO channel. However, the main conclusion is that a significant increase in channel capacity is attained when deploying repeaters mostly thanks to their ability to provide spatial multiplexing over the high-quality eigenmodes they may provide. The number of such eigenmodes is limited by the number of repeaters, deployment, and their antennas. © 2010 IEEE.
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