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- 2019
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Persson Waye, Kerstin, 1959, et al.
(författare)
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Adopting a child perspective for exposome research on mental health and cognitive development - Conceptualisation and opportunities.
- 2023
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Ingår i: Environmental research. - 0013-9351 .- 1096-0953. ; 239:Pt 1
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Tidskriftsartikel (refereegranskat)abstract
- Mental disorders among children and adolescents pose a significant global challenge. The exposome framework covering the totality of internal, social and physical exposures over a lifetime provides opportunities to better understand the causes of and processes related to mental health, and cognitive functioning. The paper presents a conceptual framework on exposome, mental health, and cognitive development in children and adolescents, with potential mediating pathways, providing a possibility for interventions along the life course. The paper underscores the significance of adopting a child perspective to the exposome, acknowledging children's specific vulnerability, including differential exposures, susceptibility of effects and capacity to respond; their susceptibility during development and growth, highlighting neurodevelopmental processes from conception to young adulthood that are highly sensitive to external exposures. Further, critical periods when exposures may have significant effects on a child's development and future health are addressed. The paper stresses that children's behaviour, physiology, activity pattern and place for activities make them differently vulnerable to environmental pollutants, and calls for child-specific assessment methods, currently lacking within today's health frameworks. The importance of understanding the interplay between structure and agency is emphasized, where agency is guided by social structures and practices and vice-versa. An intersectional approach that acknowledges the interplay of social and physical exposures as well as a global and rural perspective on exposome is further pointed out. To advance the exposome field, interdisciplinary efforts that involve multiple scientific disciplines are crucial. By adopting a child perspective and incorporating an exposome approach, we can gain a comprehensive understanding of how exposures impact children's mental health and cognitive development leading to better outcomes.
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| 3. |
- van Kamp, Irene, et al.
(författare)
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Early environmental quality and life-course mental health effects: The Equal-Life project
- 2022
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Ingår i: Environmental Epidemiology. - 2474-7882. ; 6:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: There is increasing evidence that a complex interplay of factors within environments in which children grows up, contributes to children's suboptimal mental health and cognitive development. The concept of the life-course exposome helps to study the impact of the physical and social environment, including social inequities, on cognitive development and mental health over time. Methods: Equal-Life develops and tests combined exposures and their effects on children's mental health and cognitive development. Data from eight birth-cohorts and three school studies (N = 240.000) linked to exposure data, will provide insights and policy guidance into aspects of physical and social exposures hitherto untapped, at different scale levels and timeframes, while accounting for social inequities. Reasoning from the outcome point of view, relevant stakeholders participate in the formulation and validation of research questions, and in the formulation of environmental hazards. Exposure assessment combines GIS-based environmental indicators with omics approaches and new data sources, forming the early-life exposome. Statistical tools integrate data at different spatial and temporal granularity and combine exploratory machine learning models with hypothesis-driven causal modeling. Conclusions: Equal-Life contributes to the development and utilization of the exposome concept by (1) integrating the internal, physical and social exposomes, (2) studying a distinct set of life-course effects on a child's development and mental health (3) characterizing the child's environment at different developmental stages and in different activity spaces, (4) looking at supportive environments for child development, rather than merely pollutants, and (5) combining physical, social indicators with novel effect markers and using new data sources describing child activity patterns and environments.
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| 4. |
- Botteldooren, Dick, et al.
(författare)
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An LAeq is not an LAeq.
- 2005
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Ingår i: Journal of the Acoustical Society of America. - 0001-4966. ; 117:4, s. 2616-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Classical dose response relationships for environmental noise annoyance have been based on Ldn or Lden. These exposure measures are essentially based on an energy averaging measure, LAeq. Differences between groups of sources (e.g., continuous or event based) are accounted for by using separate dose-effect relationships. In society today, one often sees that event loudness is traded for number of events which is perfectly acceptable within the LAeq based annoyance concept. Clearly a more unified theory for noise annoyance is needed to fully account for the effect of such trade-offs. In this paper a model implementing such a theory is presented. The perceptual model starts from the premises that a sound event has to be noticed for it to contribute to overall annoyance. The model accounts for the fact that noticing a noise event not only depends on the level of the event itself but also on background noise, sound insulation and acoustic characteristics of the dwelling, level of attention, etc. The severity of the effect of a noticed sound on overall annoyance is assumed to primarily depend on the signal to noise ratio. The model allows to account for modifiers such as previous exposure, noise sensitivity, and coping. The model results are compared to the findings of a recent field experiment. Conclusions based on calculated and experimental trends are presented.
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| 5. |
- De Coensel, Bert, et al.
(författare)
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A model for the perception of environmental sound based on notice-events
- 2009
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Ingår i: Journal of the Acoustical Society of America. - : Acoustical Society of America. - 0001-4966 .- 1520-8524. ; 126:2, s. 656-665
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Tidskriftsartikel (refereegranskat)abstract
- Anapproach is proposed to shed light on the mechanisms underlyinghuman perception of environmental sound that intrudes in everyday living.Most research on exposure-effect relationships aims at relating overall effectsto overall exposure indicators in an epidemiological fashion, without includingavailable knowledge on the possible underlying mechanisms. Here, it isproposed to start from available knowledge on audition and perceptionto construct a computational framework for the effect of environmentalsound on individuals. Obviously, at the individual level additional mechanisms(inter-sensory, attentional, cognitive, emotional) play a role in the perceptionof environmental sound. As a first step, current knowledge ismade explicit by building a model mimicking some aspects ofhuman auditory perception. This model is grounded in the hypothesisthat long-term perception of environmental sound is determined primarily byshort notice-events. The applicability of the notice-event model is illustratedby simulating a synthetic population exposed to typical Flemish environmentalnoise. From these simulation results, it is demonstrated that thenotice-event model is able to mimic the differences between theannoyance caused by road traffic noise exposure and railway trafficnoise exposure that are also observed empirically in other studiesand thus could provide an explanation for these differences.
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| 6. |
- Dzhambov, Angel M., et al.
(författare)
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Analytical approaches to testing pathways linking greenspace to health : A scoping review of the empirical literature
- 2020
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Ingår i: Environmental Research. - : Elsevier BV. - 0013-9351 .- 1096-0953. ; 186
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Forskningsöversikt (refereegranskat)abstract
- Background: Inadequate translation from theoretical to statistical models of the greenspace - health relationship may lead to incorrect conclusions about the importance of some pathways, which in turn may reduce the effectiveness of public health interventions involving urban greening. In this scoping review we aimed to: (1) summarize the general characteristics of approaches to intervening variable inference (mediation analysis) employed in epidemiological research in the field; (2) identify potential threats to the validity of findings; and (3) propose recommendations for planning, conducting, and reporting mediation analyses.Methods: We conducted a scoping review, searching PubMed, Scopus, and Web of Science for peer-reviewed epidemiological studies published by December 31, 2019. The list of potential studies was continuously updated through other sources until March 2020. Narrative presentation of the results was coupled with descriptive summary of study characteristics.Results: We found 106 studies, most of which were cross-sectional in design. Most studies only had a spatial measure of greenspace. Mental health/well-being was the most commonly studied outcome, and physical activity and air pollution were the most commonly tested intervening variables. Most studies only conducted single mediation analysis, even when multiple potentially intertwined mediators were measured. The analytical approaches used were causal steps, difference-of-coefficients, product-of-coefficients, counterfactual framework, and structural equation modelling (SEM). Bootstrapping was the most commonly used method to construct the 95% CI of the indirect effect. The product-of-coefficients method and SEM as used to investigate serial mediation components were more likely to yield findings of indirect effect. In some cases, the causal steps approach thwarted tests of indirect effect, even though both links in an indirect effect were supported. In most studies, sensitivity analyses and proper methodological discussion of the modelling approach were missing.Conclusions: We found a persistent pattern of suboptimal conduct and reporting of mediation analysis in epidemiological studies investigating pathways linking greenspace to health; however, recent years have seen improvements in these respects. Better planning, conduct, and reporting of mediation analyses are warranted.
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| 7. |
- Von Lindern, Eike, et al.
(författare)
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Traffic-related exposures, constrained restoration, and health in the residential context
- 2016
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Ingår i: Health and Place. - : Elsevier BV. - 1353-8292 .- 1873-2054. ; 39, s. 92-100
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Tidskriftsartikel (refereegranskat)abstract
- Traffic-related exposures may undermine the restorative character of the home, and this may in turn undermine health and residential satisfaction. We addressed this possibility with data for adults residing in a large valley near Innsbruck, Austria (N=572). We joined objective measures of traffic-related sound and air pollutants with reports from door-to-door surveys concerning perceived disturbance from traffic-related exposures, restorative qualities of the living environment, self-perceived health and residential satisfaction. We analyzed these data with successive tests of nested structural equation models, with and without the restorative quality variables. The results suggest that the negative impact of traffic-related exposures on self-perceived health and satisfaction with the living environment involves the constraint of restorative qualities of the living environment, over and above the share traditionally attributed to such exposures viewed as stressors. We discuss theoretical and practical implications of the distinction between environmental stressors and constraints on restoration.
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