| 121. |
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| 122. |
- Li, Hui-xiang, et al.
(författare)
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[Expressions of thymidine phosphorylase, thymidylate synthase and dihydropyrimidine dehydrogenase in breast cancer and their correlations with prognosis]
- 2004
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Ingår i: Zhonghua zhong liu za zhi [Chinese journal of oncology]. - Beijing, China : Zhongguo Yixue Kexueyuan / Cancer Hospital, Chinese Academy of Medical Sciences. - 0253-3766. ; 26:11, s. 669-672
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To study the expression of thymidine phosphorylase (TP), thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) mRNA in breast cancer and its correlation with prognosis.Methods: Expression levels of TP, TS and DPD mRNA in 86 micro-selected breast cancer tissues and 9 normal breast tissues were detected by real-time quantitative PCR.Results: The median expression levels of TP, TS and DPD mRNA in tumor tissue and in normal tissues were 16.54, 0.38, 2.47 and 11.75, 0.25, 8.33, respectively, there were no significant differences (P >0.05). The expression levels of TP, TS and DPD mRNA showed no association with tumor size, lymph node metastasis, pathological grade and clinical stage, except that of DPD showed a negative association with patients' ages. There was no significant difference in disease-free survival or overall survival between the patients with high and low TP or DPD mRNA levels. Disease-free survival tends to be better in the patients with low TS mRNA level than those with high TS mRNA, but the difference was not significant (P=0.069), while the overall survival showed a statistically difference (59.00 month and 70.30 month) (P=0.0496).Conclusion: The expression level of TS mRNA may serve as a prognostic marker for breast cancer patients.
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| 123. |
- Li, Huixiong, et al.
(författare)
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蒸汽-冷流体接触冷凝流动的数值模拟
- 2005
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Ingår i: Gongcheng Rewuli Xuebao. - Beijing, China. - 0253-231X. ; 26, s. 963-966
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Tidskriftsartikel (refereegranskat)abstract
- 介绍了关于蒸汽-冷流体直接接触冷凝流动与传热的数值计算模型与部分研究结果。用Level Set方法确定蒸汽-冷流体接触界面的位置和形状,建立了对蒸汽和冷流体普遍适用的动量、能量和质量守恒方程,在能量和质量寺恒方程中增加了部分项用于计算蒸汽冷凝所产生的影响。用有限差分法在交错网格上离散控制方程,用Runge-Kutta法-五阶WENO组合格式求解Level Set输运方程,用压力修正的迭代Projection方法求解动量方程,而用SIMPLE方法求解温度控制方程。对算例的计算结果表明,本文所建立的数值计算模型能反映物理现象的宏观特性。根据计算结果,分析了本文模型的优缺点,并指出了今后改进的方向。
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| 124. |
- Li, Kai, et al.
(författare)
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Metal thermopile infrared detector with vertical graphene
- 2023
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Ingår i: Wuli Xuebao/Acta Physica Sinica. - : Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences. - 1000-3290. ; 72:3
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Tidskriftsartikel (refereegranskat)abstract
- Thermopile infrared detector is a kind of detector device mainly composed of thermocouple as the basic unit. Because of its simple principle, no need of cooling equipment, and other advantages, it has been widely used in various fields of production and life. However, the absorption rates of the materials in conventional thermopile devices are poor, and the majority of them are incompatible with microfabrication methods. In this work, a metal thermopile infrared detector with vertical graphene (VG) is designed and fabricated. The VG is grown via plasma enhanced chemical vapor deposition, and retained at the device’s thermal ends to provide the thermopile IR detector’s wideband and high response characteristics. The detector achieves a room temperature responsivity reaching a value as high as 1.53 V/W at 792 nm, which can increase the response results about 28 times and reduce the response time to 0.8 ms compared with the thermopile detector without VG. After systematically measuring the response results, it is finally found that there are three main mechanisms responsible for the response on the composite device. The first one is the response generated by the metal thermopile itself alone. The second one is the response increased eventually by the contribution of VG covered at the metal thermal junction that expands the temperature difference. The last one is the response generated by the temperature gradient existing inside the VG on the surface of the device after the absorption of heat. The portion of each partial response mechanism in the total response is also analyzed, providing a new reference direction for analyzing the response generation mechanism of thermopile detectors with other absorbing materials. The process is compatible with the microfabrication, while the device performance is enhanced and suitable for mass production. Furthermore, by utilizing the surface plasmon resonance to combine VG with metal nanoparticles, the material’ s light absorption is found to be enhanced significantly under the same conditions, and the resulting thermal voltage can be increased to 6 times. The results indicate that VG promises to possess practical applications, in many fields such as photoelectric sensing and power production devices. This technology provides a new method to manufacture high-performance thermopile infrared detectors and other sensor devices.
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| 125. |
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| 126. |
- Li, L, et al.
(författare)
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Damage coupled thermo-mechanical model for rock failure process and applications
- 2006
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Ingår i: CHINESE JOURNAL OF THEORETICAL AND APPLIED MECHANICS. - 0459-1879. ; 38:4, s. 505-513
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Tidskriftsartikel (refereegranskat)abstract
- Based on the heterogeneous characteristics of rock at mesoscopic level, the thermo-mechanical (TM) coupled behavior during the failure process of rock subjected to thermal stress is analyzed with elastic damage mechanics and thermo-elastic theory. A mesoscopic TM coupling model, implemented in rock fracture process analysis (RFPA), is proposed, which can be used to study the damage and failure process, as well as elastic stress for the coupled TM rock problem. With the numerical model, the damage and associated mechanical properties evolution of mesoscopic structure in rocks subjected to TM loading can be analyzed. Numerical simulation is carried out to investigate the stability of the rock pillar in a hard rock laboratory. The numerically obtained stress field, failure pattern of pillar rock and associated acoustic emission (AE) events all agree well with the in-situ data, which shows that the proposed model is reasonable and effective, and may provide guides for the experiment design and associated applications
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| 127. |
- Li, Liangxing, et al.
(författare)
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冷中子源冷包截面含汽率数理模型探讨
- 2005
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Ingår i: Proceedings of the 11<sup>th</sup> Annual Meeting of Chinese Engineering Thermophysics.
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Konferensbidrag (refereegranskat)
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| 128. |
- Li, Liangxing, et al.
(författare)
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冷中子源冷包截面含汽率数理模型探讨
- 2007
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Ingår i: Gongcheng Rewuli Xuebao. - Beijing, China. - 0253-231X. ; 28, s. 64-67
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Tidskriftsartikel (refereegranskat)abstract
- 文章推导出一种计算冷包截面含汽率的数学模型;将模型计算结果与已知文献相关实验结果进行对比,验证了模型的正确性.利用该模型探讨了冷包截面含汽率的影响因素如气泡直径,工质液体的密度、粘性,加热功率等.模型计算表明:气泡直径越大,在同一截面高度处的截面含汽率越低;工质粘性越大,在同一截面高度处的截面含汽率越高.本文模型的计算结果能对冷包设计提供理论支持.
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| 129. |
- Li, Liangxing, et al.
(författare)
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熔融液滴与冷却剂相互作用实验中液滴释放控制机构的研制
- 2008
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Ingår i: Hedongli Gongcheng. - ChengDu, China. - 0258-0926. ; 29, s. 42-45
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Tidskriftsartikel (refereegranskat)abstract
- 在高温熔融液滴与冷却剂相互作用的实验中,熔融液滴的释放控制对整个实验起至关重要的作用。本文在以往实验机械控制装置的基础上,自主设计一个自动控制电路来代替人工机械操作,利用控制电路给电磁铁提供瞬时脉冲来控制液滴瞬时释放下落,简化实验的可持续性操作,提高实验的重复性、精确性和操作方便性。
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| 130. |
- Li, Liangxing, et al.
(författare)
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熔融液滴在冷却剂中的运动特性实验
- 2007
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Ingår i: Hedongli Gongcheng. - Chengdu, China. - 0258-0926. ; 28, s. 36-41
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Tidskriftsartikel (refereegranskat)abstract
- 设计、建立了研究高温熔融液滴与冷却剂相互作用的可视化实验装置,通过高速摄影记录熔融液滴的下落过程,获得了下落小球运动过程曲线,重点考察了液滴温度和冷却剂温度对液滴-冷却剂界面作用过程的影响。结果表明,熔融液滴穿过气-水界面后,将首先经历一个速度骤降-回升过程,之后液滴作减速运动下落;当冷却水温度一定时,高温熔融液滴温度越高,熔融液滴入水后下落速度越快;当熔融液滴温度一定时,冷却水温度越高,熔融液滴入水后下落速度越快。
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