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Träfflista för sökning "WFRF:(Olsson K) srt2:(1980-1984)"

Sökning: WFRF:(Olsson K) > (1980-1984)

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1.
  • Auer, R. N., et al. (författare)
  • The distribution of hypoglycemic brain damage
  • 1984
  • Ingår i: Acta Neuropathologica. - 0001-6322. ; 64:3, s. 177-191
  • Tidskriftsartikel (refereegranskat)abstract
    • Rats were exposed to insulin-induced hypoglycemia resulting in periods of cerebral isoelectricity ranging from 10 to 60 min. After recovery with glucose, they were allowed to wake up and survive for 1 week. Control rats were recovered at the stage of EEG slowing. After sub-serial sectioning, the number and distribution of dying neurons was assessed in each brain region. Acid fuchsin was found to stain moribund neurons a brilliant red. Brains from control rats showed no dying neurons. From 10 to 60 min of cerebral isoelectricity, the number of dying neurons per brain correlated positively with the number of minutes of cerebral isoelectricity up to the maximum examined period of 60 min. Neuronal necrosis was found in the major brain regions vulnerable to several different insults. However, within each region the damage was not distributed as observed in ischemia. A superficial to deep gradient in the density of neuronal necrosis was seen in the cerebral cortex. More severe damage revealed a gradient in relation to the subjacent white matter as well. The caudatoputamen was involved more heavily near the white matter, and in more severely affected animals near the angle of the lateral ventricle. The hippocampus showed dense neuronal necrosis at the crest of the dentate gyrus and a gradient of increasing selective neuronal necrosis medially in CA1. The CA3 zone, while relatively resistant, showed neuronal necrosis in relation to the lateral ventricle in animals with hydrocephalus. Sharp demarcations between normal and damaged neuropil were found in the hippocampus. The periventricular amygdaloid nuclei showed damage closest to the lateral ventricles. The cerebellum was affected first near the foramina of Luschka, with damage occurring over the hemispheres in more severely affected animals. Purkinje cells were affected first, but basket cells were damaged as well. Rare necrotic neurons were seen in brain stem nuclei. The spinal cord showed necrosis of neurons in all areas of the gray matter. Infarction was not seen in this study. The possibility is discussed that a neurotoxic substance borne in the tissue fluid and cerebrospinal fluid (CSF) contributes to the pathogenesis of neuronal necrosis in hypoglycemic brain damage.
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4.
  • Göransson, L., et al. (författare)
  • Effects of different handling systems on pig feed quality
  • 1982
  • Ingår i: Animal Feed Science and Technology. - : Elsevier BV. - 0377-8401 .- 1873-2216. ; 7:1, s. 11-26
  • Tidskriftsartikel (refereegranskat)abstract
    • Separation of feed mixtures and its effect on the production traits of growing-finishing pigs was studied in three experiments. In Experiments I and II the effects of different types of equipment to prevent separation in a silo were studied. Experiment III dealt with separation along a feed transport chain. Experiments I and II clearly demonstrated an increase in feed quality variation by filling a silo without any arrangement to reduce separation. The last feed to be extracted from a silo filled in this manner showed an increasing amount of small particles and contents of crude fibre and ash, a decrease in the bulk density and also in the digestibility of nutrients and in the performance of the pigs. Filling a silo equipped with chutes by an auger or pneumatically through a cyclone did not create separation problems, and consequently there were no differences between these treatments in the production experiments. Separation measured by particle size, bulk density or chemical composition was not noticeable along the feed transport chain (Experiment III). There was no effect on performance of the pigs of their location along the chain. © 1982.
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