| 1. |
- Middeldorp, Christel M., et al.
(författare)
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia : design, results and future prospects
- 2019
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Ingår i: European Journal of Epidemiology. - : Springer Science and Business Media LLC. - 0393-2990 .- 1573-7284. ; 34:3, s. 279-300
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Tidskriftsartikel (refereegranskat)abstract
- The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.
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| 2. |
- Yin, X., et al.
(författare)
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Vertical Sandwich Gate-All-Around Field-Effect Transistors with Self-Aligned High-k Metal Gates and Small Effective-Gate-Length Variation
- 2020
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Ingår i: IEEE Electron Device Letters. - : Institute of Electrical and Electronics Engineers Inc.. - 0741-3106 .- 1558-0563. ; 41:1, s. 8-11
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Tidskriftsartikel (refereegranskat)abstract
- A new type of vertical nanowire (NW)/nanosheet (NS) field-effect transistors (FETs), termed vertical sandwich gate-all-around (GAA) FETs (VSAFETs), is presented in this work. Moreover, an integration flow that is compatible with processes used in the mainstream industry is proposed for the VSAFETs. Si/SiGe epitaxy, isotropic quasi-atomic-layer etching (qALE), and gate replacement were used to fabricate pVSAFETs for the first time. Vertical GAA FETs with self-aligned high-k metal gates and a small effective-gate-length variation were obtained. Isotropic qALE, including Si-selective etching of SiGe, was developed to control the diameter/thickness of the NW/NS channels. NWs with a diameter of 10 nm and NSs with a thickness of 20 nm were successfully fabricated, and good device characteristics were obtained. Finally, the device performance was investigated and is discussed in this work. © 2019 IEEE.
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| 3. |
- Stolte, W.C., et al.
(författare)
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The K-shell Auger decay of atomic oxygen
- 1997
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Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - 0953-4075. ; 30:20, s. 4489-4497
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Tidskriftsartikel (refereegranskat)abstract
- Relative photoionization cross sections for O+ and O2+ produced by the Auger decay of a 1s hole in atomic oxygen were measured by using synchrotron radiation between 525 and 553 eV. Energies and quantum defects of the members of the two Rydberg series converging to [1s]2s22p4(4P) and [1s]2s22p4(2P) ionization thresholds were determined. In addition, the 2P and 4P ionization thresholds were calculated from the two Rydberg series. The 182 meV resolution of the monochromator allowed a detailed study over both thresholds revealing evidence for post-collision interaction and allowing a comparison of the ionization continuum above both 2P and 4P thresholds with that of the ionization continuum above the Ar L2 and L3 edges. This comparison indicates that the lifetimes of the Ar(2p) and O(1s) hole states are approximately the same.
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| 4. |
- Dong, G J, et al.
(författare)
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Cold molecules in pulsed optical lattices
- 2005
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Ingår i: Progress in Quantum Electronics. - : Elsevier BV. - 0079-6727 .- 1873-1627. ; 29:1, s. 1-58
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Forskningsöversikt (refereegranskat)abstract
- We review recent theoretical studies on the dynamics of molecules in pulsed optical lattices. These lattices are periodic potential wells formed by the interaction between two counter propagating far-off resonant optical fields and the molecules. We show that the molecules can be manipulated in both constant velocity and accelerating lattices for a number of applications. We first study a molecular optical mirror through the reflections of molecules by a stationary optical lattice and show that the reflectivity can be significantly improved by optimizing the pulse duration. When reflection occurs from a moving lattice, we show that molecules can brought to rest when the lattice velocity is half the molecular velocity, demonstrating a new and efficient method for creating slow cold molecules. We further describe a microlinear accelerator for molecules produced by an accelerating optical lattice, which is achieved by frequency chirping one of the two optical fields. The molecules trapped by the potential wells of the lattice are accelerated to high velocities (10-100km/s) over micron-size distance within nanosecond time scales. When the lattice is decelerated, the trapped molecules can be slowed to zero velocity, offering an alternate method for producing slow cold molecules. Molecules that are not trapped in the accelerating lattice can be temporarily localized around a characteristic velocity,. which is uniquely dependent on the mass-to-polarizability ratio. We show that this feature can be used for a new form of time-of-flight mass spectrometry for chemical analysis of a mixture.
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| 5. |
- Dong, G J, et al.
(författare)
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Super-Gaussian mirror for high-field-seeking molecules
- 2005
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Ingår i: Physical Review A. Atomic, Molecular, and Optical Physics. - 1050-2947 .- 1094-1622. ; 72:3
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Tidskriftsartikel (refereegranskat)abstract
- A matter wave mirror using a single, pulsed, super-Gaussian (SG) optical beam for specular reflection of neutral ground-state molecules is studied. The mirror has a high reflectivity close to 100% and nearly perfect specular reflection over a large incident angle. This mirror avoids the usual problems due to surface roughness and the van der Waals interactions that occur in conventional atomic mirrors. Further, it is capable of reflectance and transmittance with applications to velocity filtering and deceleration of cold molecules.
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