| 11. |
- Allwood, Jens, 1947, et al.
(författare)
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Work on Spoken (Multimodal) Corpora in South Africa.
- 2010
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Ingår i: Calzolari, N, Choukri, K. Maegaard, B, Mariani, J., Odijk, J, Piperidis, S, Rosner, M. & Tapias, D. (Eds.) Proceedings of the Seventh conference on International Language Resources and Evaluation (LREC'10) Valetta, Malta May 19-21. European Language Resources Association (ELRA). http://www.lrec-conf.org/proceedings/lrec2010/index.html (ALLWOOD 10.438).. - 2951740867
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Konferensbidrag (refereegranskat)
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| 12. |
- Almanasreh, Hasan, 1981
(författare)
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The Dirac Operator; From Numerics to the Theory of G-convergence
- 2010
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- We consider two main issues concerning the Dirac operator, the first is widely known as the appearance of spurious eigenvalues within the spectrum. The second is the study of the asymptotic behavior of the eigenvalues for a family of Dirac operators with oscillatory potential added to the Coulomb-Dirac Hamiltonian. In the first problem a stable Finite element scheme is used to treat the problem of spuriousity of the radial Dirac operator with a Coulomb potential. The numerical accuracy depends strongly on the derivation of a fine-intrinsic stability parameter. In the second problem we consider the Coulomb-Dirac operator with addition to an abstract oscillating potential. Using the spectral measure of operators we project into the positive part of the perturbed Hamiltonian. By using G-convergence theory of positive self-adjoint operators in Hilbert spaces and ¡- convergence of the associated quadratic functionals we prove G-compactness for a family of positive Dirac operators under certain assumptions on the potentials.
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| 13. |
- Almotairi, Badi, 1970, et al.
(författare)
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Information Flows Supporting Hinterland Transport: Applications in Sweden
- 2010
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Ingår i: Dryport Conference, Edinburgh, 21-22 October.
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Konferensbidrag (refereegranskat)abstract
- This article analyses how information and communication technology (ICT) is used to support hinterland transport of maritime containers. The focus is on how information is conveyed between actors using an ICT facility structure and how integrative information is used by different partners’ information systems for making the different transport operations more efficient and enabling an improved service offer. The analysis includes identification of the actor network and the management components in line with supply chain management (SCM) perspectives. To support this analysis a conceptual model showing the relationship between the integrative information and integrative technology was constructed and related to business process and an ICT maturity model found in the literature. Interviews have been conducted with actors involved in Swedish hinterland rail transport. The information flows have been mapped and the analysis shows that the current level of integration and ICT maturity is fairly low, but that several actors currently are modernising their systems. Their main motivation is to reduce the administrative tasks, rather than achieving a supply chain integration. The article shows that a proper handling of the information flow opens up for new business models and can make existing models more efficient. The ICT system must support the proper integration of the ocean, seaport and hinterland parts of the transport chain as well as auxiliary services.
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| 14. |
- Almqvist, Sofia, 1980, et al.
(författare)
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Amelogenin is phagocytized and induces changes in integrin configuration, gene expression and proliferation of cultured human dermal fibroblasts
- 2010
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Ingår i: Journal of Materials Science. Materials in Medicine. - : Springer Science and Business Media LLC. - 1573-4838 .- 0957-4530. ; 21:3
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Tidskriftsartikel (refereegranskat)abstract
- Fibroblasts are central in wound healing by expressing important mediators and producing and remodelling extracellular matrix (ECM) components. This study aimed at elucidating possible mechanisms of action of the ECM protein amelogenin on normal human dermal fibroblasts (NHDF). Amelogenin at 100 and 1000 μg/ml increased binding of NHDF via several integrins, including αvβ3, αvβ5 and α5β1. Further, both surface interaction and cellular uptake of amelogenin by NHDF was observed using scanning and transmission electron microscopy. Gene microarray studies showed >8-fold up or down-regulation of genes, of which most are involved in cellular growth, migration and differentiation. The effect of amelogenin was exemplified by increased proliferation over 7 days. In conclusion, the beneficial effects of amelogenin on wound healing are possibly conducted by stimulating fibroblast signalling, proliferation and migration via integrin interactions. It is hypothesized that amelogenin stimulates wound healing by providing connective tissue cells with a temporary extracellular matrix.
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| 15. |
- Amundsen, Silja Svanström, et al.
(författare)
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Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort.
- 2010
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Ingår i: Genes and immunity. - : Springer Science and Business Media LLC. - 1476-5470 .- 1466-4879. ; 11:1, s. 79-86
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Tidskriftsartikel (refereegranskat)abstract
- Recent genome-wide association studies have identified 1q31 (RGS1), 2q11-12 (IL18RAP), 3p21 (CCR1/CCR3/CCR2), 3q25-26 (IL12A/SCHIP1), 3q28 (LPP), 4q27 (IL2/IL21), 6q25 (TAGAP) and 12q24 (SH2B3) as susceptibility regions for coeliac disease (CD). We have earlier replicated association with the IL2/IL21 region. This study aimed at replicating the remaining regions in a family cohort using the transmission disequilibrium test, which is not prone to population stratification as a source of false-positive results. Nine single nucleotide polymorphisms (SNPs) within these regions were genotyped in 325 Swedish-Norwegian CD families. We found significant associations with the same alleles in the regions 1q31 (rs2816316; P(nc)=0.0060), 3p21 (rs6441961; P(nc)=0.0006), 3q25-26 (rs17810564; P(nc)=0.0316 and rs9811792; P(nc)=0.0434) and 3q28 (rs1464510; P(nc)=0.0037). Borderline, but non-significant, associations were found for rs917997 (IL18RAP), whereas no evidence for association could be obtained for rs13015714 (IL18RAP) or rs1738074 (TAGAP). The lack of replication of the latter SNPs could be because of limited power. rs3184504 (SH2B3) was not analysed because of assay failure. The most significantly associated region, 3p21 (CCR1/CCR3/CCR2), was further analysed by typing of 30 SNPs, with the aim of identifying the causal variant responsible for the initial association. Several SNPs showed association with CD, but none displayed associations stronger than rs6441961, nor did any of them add to the effect initially marked by rs6441961 in a conditional analysis. However, differential effects of rs6441961(*)C carrying haplotypes were indicated, and we thus cannot exclude the possibility that our inability to obtain evidence for multiple independent effects in the CCR1/CCR3/CCR2 gene region was related to a power issue.
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| 16. |
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| 17. |
- Andersson, Mats, 1957
(författare)
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A residue criterion for strong holomorphicity
- 2010
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Ingår i: Arkiv för matematik. - : International Press of Boston. - 0004-2080 .- 1871-2487. ; 48:1, s. 1-15
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Tidskriftsartikel (refereegranskat)abstract
- We give a local criterion in terms of a residue current for strong holomorphicity of a meromorphic function on an arbitrary pure-dimensional analytic variety. This generalizes a result by A. Tsikh for the case of a reduced complete intersection.
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| 18. |
- Andersson, Mats, 1957, et al.
(författare)
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Decomposition of Residue Currents
- 2010
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Ingår i: J reine angew Math. ; 638, s. 103-118
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 19. |
- Andersson, Mats, 1957, et al.
(författare)
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On the Briancon-Skoda theorem on a singular variety
- 2010
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Ingår i: Annales de l'institut Fourier. - : Cellule MathDoc/CEDRAM. - 0373-0956 .- 1777-5310. ; 60:2, s. 417-432
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Tidskriftsartikel (refereegranskat)abstract
- Let Z be a germ of a reduced analytic space of pure dimension. We provide an analytic proof of the uniform Briancon-Skoda theorem for the local ring Oz; a result which was previously proved by Huneke by algebraic methods. For ideals with few generators we also get much sharper results.
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| 20. |
- Andersson, Niklas, 1970, et al.
(författare)
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A variant near the interleukin-6 gene is associated with fat mass in Caucasian men
- 2010
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Ingår i: International Journal of Obesity. - : Springer Science and Business Media LLC. - 0307-0565 .- 1476-5497. ; 34:6, s. 1011-9
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Tidskriftsartikel (refereegranskat)abstract
- CONTEXT: Regulation of fat mass appears to be associated with immune functions. Studies of knockout mice show that endogenous interleukin (IL)-6 can suppress mature-onset obesity. OBJECTIVE: To systematically investigate associations of single nucleotide polymorphisms (SNPs) near the IL-6 (IL6) and IL-6 receptor (IL6R) genes with body fat mass, in support for our hypothesis that variants of these genes can be associated with obesity. DESIGN AND STUDY SUBJECTS: The Gothenburg Osteoporosis and Obesity Determinants (GOOD) study is a population-based cross-sectional study of 18- to 20-year-old men (n=1049), from the Gothenburg area (Sweden). Major findings were confirmed in two additional cohorts consisting of elderly men from the Osteoporotic Fractures in Men (MrOS) Sweden (n=2851) and MrOS US (n=5611) multicenter population-based studies. MAIN OUTCOME: The genotype distributions and their association with fat mass in different compartments, measured with dual-energy X-ray absorptiometry. RESULTS: Out of 18 evaluated tag SNPs near the IL6 and IL6R genes, a recently identified SNP rs10242595 G/A (minor allele frequency=29%) 3' of the IL6 gene was negatively associated with the primary outcome total body fat mass (effect size -0.11 standard deviation (s.d.) units per A allele, P=0.02). This negative association with fat mass was also confirmed in the combined MrOS Sweden and MrOS US cohorts (effect size -0.05 s.d. units per A allele, P=0.002). When all three cohorts were combined (n=8927, Caucasian subjects), rs10242595(*)A showed a negative association with total body fat mass (effect size -0.05 s.d. units per A allele, P<0.0002). Furthermore, the rs10242595(*)A was associated with low body mass index (effect size -0.03, P<0.001) and smaller regional fat masses. None of the other SNPs investigated in the GOOD study were reproducibly associated with body fat. CONCLUSIONS: The IL6 gene polymorphism rs10242595(*)A is associated with decreased fat mass in three combined cohorts of 8927 Caucasian men.
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