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- Sartelli, Massimo, et al.
(författare)
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Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action
- 2023
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Ingår i: WORLD JOURNAL OF EMERGENCY SURGERY. - 1749-7922. ; 18:1
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Forskningsöversikt (refereegranskat)abstract
- Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice.
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| 2. |
- Kooij, J. J. S., et al.
(författare)
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Updated European Consensus Statement on diagnosis and treatment of adult ADHD
- 2019
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Ingår i: European psychiatry. - : Cambridge University Press (CUP). - 0924-9338 .- 1778-3585. ; 56, s. 14-34
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundAttention-deficit/hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD is currently underdiagnosed and undertreated in many European countries, leading to chronicity of symptoms and impairment, due to lack of, or ineffective treatment, and higher costs of illness.MethodsThe European Network Adult ADHD and the Section for Neurodevelopmental Disorders Across the Lifespan (NDAL) of the European Psychiatric Association (EPA), aim to increase awareness and knowledge of adult ADHD in and outside Europe. This Updated European Consensus Statement aims to support clinicians with research evidence and clinical experience from 63 experts of European and other countries in which ADHD in adults is recognized and treated.ResultsBesides reviewing the latest research on prevalence, persistence, genetics and neurobiology of ADHD, three major questions are addressed: (1) What is the clinical picture of ADHD in adults? (2) How should ADHD be properly diagnosed in adults? (3) How should adult ADHDbe effectively treated?ConclusionsADHD often presents as a lifelong impairing condition. The stigma surrounding ADHD, mainly due to lack of knowledge, increases the suffering of patients. Education on the lifespan perspective, diagnostic assessment, and treatment of ADHD must increase for students of general and mental health, and for psychiatry professionals. Instruments for screening and diagnosis of ADHD in adults are available, as are effective evidence-based treatments for ADHD and its negative outcomes. More research is needed on gender differences, and in older adults with ADHD.
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| 4. |
- Barron, Jennie, et al.
(författare)
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Coping with Rainfall Variability : Dry Spell Mitigation and Implication on Landscape Water Balances in Small-scale Farming Systems in Semi-arid Niger
- 2010
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Ingår i: International Journal of Water Resources Development. - : Informa UK Limited. - 0790-0627 .- 1360-0648. ; 26:4, s. 543-559
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Tidskriftsartikel (refereegranskat)abstract
- Rainfall variability and inherent dry spells are a reality with severe implications for smallholder agro-ecosystems in semi-arid Sahel. To increase both on- and off-farm biomass production and productivity is challenging with these climate-induced temporal and spatial variations of water. This paper tests the idea that increased vegetation through tree cover may impact water balance in a water-stressed landscape: South-east Niger. Local rainfall data, farming systems data and a landscape water-modelling tool (ArcSWAT) are used. Four production domains (conventional or fertilized combined with millet crop or millet crop plus trees) were assessed for long-term yield and landscape water balance impacts. The dry-spell analysis shows a frequency of dry spells less than 14 days is in the order of one to two dry-spell events per season in 7 years out of 10 years. The occurrence has increased between 1960 and 2004, despite a slight recovery of total annual rainfall amounts since the severe droughts of the 1980s. Results of modelled millet yields and landscape water balances suggest that options exist to enhance landscape productivity. With marginal inputs of fertilizer, millet yields increased fivefold to 2.0-2.4tha-1, and water productivity improved from 6,000 to 12,000m3 actual evapotranspiration (ETa) t-1 grain, to an improved 1,700-3,000m3 ETa t-1 grain. In addition, 10% tree cover in combination with fertilized millet increased yield with marginal or no impact on water partitioning and flows in the landscape. The policy opportunities are complex and urgently needed in view of increased rainfall variability due to expected climate change. To develop sustainable pathways in these landscapes dominated by poor smallholder framers requires water managers to be more innovative and go beyond water resources alone.
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