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| 2. |
- Cochemé, Helena M, et al.
(författare)
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Mitochondrial targeting of quinones: therapeutic implications.
- 2007
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Ingår i: Mitochondrion. - : Elsevier BV. - 1567-7249. ; 7 Suppl, s. S94-102
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Forskningsöversikt (refereegranskat)abstract
- Mitochondrial oxidative damage contributes to a range of degenerative diseases. Ubiquinones have been shown to protect mitochondria from oxidative damage, but only a small proportion of externally administered ubiquinone is taken up by mitochondria. Conjugation of the lipophilic triphenylphosphonium cation to a ubiquinone moiety has produced a compound, MitoQ, which accumulates selectively into mitochondria. MitoQ passes easily through all biological membranes and, because of its positive charge, is accumulated several hundred-fold within mitochondria driven by the mitochondrial membrane potential. MitoQ protects mitochondria against oxidative damage in vitro and following oral delivery, and may therefore form the basis for mitochondria-protective therapies.
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| 3. |
- Chen, Xingxing, et al.
(författare)
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Control of fluorescence enhancement and directionality upon excitations in a thin-film system
- 2015
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Ingår i: Physica status solidi. B, Basic research. - : Wiley. - 0370-1972 .- 1521-3951. ; 252:10, s. 2222-2229
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Tidskriftsartikel (refereegranskat)abstract
- Nanostructures with various configurations have been extensively used to engineer the emission properties of embedded fluorophores, but lack the flexibility to dynamically control fluorescence. Here we report a thin-film cavity system, comprising a quarter wavelength thick dye-doped dielectric coating on a reflecting surface, in which the fluorescence enhancement and directionality can be significantly modified by altering the illumination angle. The configuration of the cavity yields absorption properties that are highly dependent on illumination angles, due to the coupling between molecular absorption and Fabry-Perot resonances. Therefore the fluorescence intensity relating to the angle-dependent absorbing efficiency varies with illumination angles. In addition, as a result of synergy between intrinsic absorption of the reflecting surface, Fabry-Perot and surface-plasmon-polariton resonances and illumination-angle dependent excitation efficiencies for differently located molecules, the global emission intensity, including emission from dyes at all locations, can be directionally redistributed by altering the illumination angle.
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| 4. |
- Chen, Xingxing, et al.
(författare)
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Illumination Dependent Optical Properties of Plasmonic Nanorods Coupled to Thin-Film Cavities
- 2016
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Ingår i: Plasmonics. - : Springer Science and Business Media LLC. - 1557-1955 .- 1557-1963. ; 11:4, s. 1101-1107
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Tidskriftsartikel (refereegranskat)abstract
- The scattering spectra and intensity of gold nanorods placed at varied distances above gold films have been simulated and measured under various conditions, demonstrating that scattering characteristics of the nanorod-film system are highly dependent on illumination conditions. Studying the surrounding electric fields of nanorods reveals that the illumination-dependent properties of the system are induced by the interference in the nanorod-film system. Both simulations and experiments show that optimising the nanorod-film distance can greatly enhance scattering magnitudes up to similar to 20 times for certain illumination conditions. We propose an application of the studied system in facilitating photo-thermal conversion.
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| 5. |
- Chen, Xingxing, et al.
(författare)
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Probing Plasmonic Gap Resonances between Gold Nanorods and a Metallic Surface
- 2015
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Ingår i: The Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 119:32, s. 18627-18634
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Tidskriftsartikel (refereegranskat)abstract
- The plasmonic resonances in individual gold nanorods nanoscopically coupled to a gold film with different gap spacing have been experimentally and theoretically investigated. The spectral widths, wavelengths, and optical polarizabilities of the maxima in measured single-nanopartide scattering spectra are significantly modified as the gap distance changes in the sub-20 nm domain. Comparing the experimental data with numerical simulations reveals that these modifications arise from the complex hybridization of several dipolar and multipolar plasmon modes that are strongly localized at the gap. These plasmon gap modes have distinct resonant and spatial characteristics as a result of near-field interaction between the elongated nanorods and the gold film. Additionally, the excitation of these gap modes is highly dependent on the gap spacing. Finally, we also discuss influences of these plasmonic modes on absorption properties of the system and propose a potential application of the studied structures in facilitating photothermal conversion.
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| 6. |
- Ding, Boyang, et al.
(författare)
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Manipulating light absorption in dye-doped dielectric films on reflecting surfaces
- 2014
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Ingår i: Optics Express. - 1094-4087. ; 22:21, s. 25965-25975
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Tidskriftsartikel (refereegranskat)abstract
- We experimentally and numerically developed a tunable absorbing nanoscale thin-film system, comprising of dye molecules doped dielectric coatings on reflecting surfaces, the absorption behaviors of which can be flexibly tuned by adjusting the system parameters, i.e. the coating thickness and the doping concentration of dye molecules. Specifically, with appropriate system parameters, our absorbing thin-film system exhibits very directional and polarization dependent absorption properties, which can be significantly altered if applied with different parameters. Calculations demonstrate the unique absorption behaviors are a result of coupling between molecular absorption and Fabry-Perot resonances in the thin-film cavity. In addition, we theoretically show that both the spectral and directional range of the absorption in the thin-film system can be intentionally regulated by doping dyes with different absorption band and setting proper excitation conditions of Fabry-Perot resonances.
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