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Numrering	Referens	Omslagsbild	Hitta
1.	Bancroft, EK, et al. (författare) Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study 2014 Ingår i: European urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 66:3, s. 489-499 Tidskriftsartikel (refereegranskat)
2.	Bancroft, EK, et al. (författare) Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations 2019 Ingår i: BJU international. - : Wiley. - 1464-410X .- 1464-4096. ; 123:2, s. 284-292 Tidskriftsartikel (refereegranskat)
3.	Jichlinski, P, et al. (författare) Hexyl aminolevulinate fluorescence cystoscopy: new diagnostic tool forphotodiagnosis of superficial bladder cancer--a multicenter study. 2003 Ingår i: J Urol. ; 170, s. 226- Tidskriftsartikel (refereegranskat)
4.	Stranne, Johan, 1970, et al. (författare) SPCG-15 : a prospective randomized study comparing primary radical prostatectomy and primary radiotherapy plus androgen deprivation therapy for locally advanced prostate cancer 2018 Ingår i: Scandinavian journal of urology. - : Medical Journals Sweden AB. - 2168-1805 .- 2168-1813. ; 52:5-6, s. 313-320 Tidskriftsartikel (refereegranskat)abstract Objective: To describe study design and procedures for a prospective randomized trial investigating whether radical prostatectomy (RP) ± radiation improves cause-specific survival in comparison with primary radiation treatment (RT) and androgen deprivation treatment (ADT) in patients with locally advanced prostate cancer (LAPC).Materials and methods: SPCG-15 is a prospective, multi-centre, open randomized phase III trial. Patients are randomized to either standard (RT + ADT) or experimental (RP with extended pelvic lymph-node dissection and with addition of adjuvant or salvage RT and/or ADT if deemed necessary) treatment. Each centre follows guidelines regarding the timing and dosing of postoperative RT and adjuvant treatment such as ADT The primary endpoint is cause-specific survival. Secondary endpoints include metastasis-free and overall survival, quality-of-life, functional outcomes and health-services requirements. Each subject will be followed up for a minimum of 10 years.Results: Twenty-three centres in Denmark, Finland, Norway and Sweden, well established in performing RP and RT for prostate cancer participated. Each country’s sites were coordinated by national coordinating investigators and sub-investigators for urology and oncology. Almost 400 men have been randomized of the stipulated 1200, with an increasing rate of accrual.Conclusions: The SPCG-15 trial aims to compare the two curatively intended techniques supplying new knowledge to support future decisions in treatment strategies for patients with LAPC The Scandinavian healthcare context is well suited for performing multi-centre long-term prospective randomized clinical trials. Similar care protocols and a history of entirely tax-funded healthcare facilitate joint trials.

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Resultat 1-4 av 4

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Typ av publikation: tidskriftsartikel (4)

Typ av innehåll: refereegranskat (4)

Författare/redaktör: Griffiths, J. (2); Hoffman, J. (2); Kirk, J. (2); Davidson, R. (2); Patel, N. (2); Cook, J. (2); visa fler...; Scott, R. (2); Friedman, E. (2); Kumar, P. (2); Murphy, D. (2); Williams, R. (2); Castro, E (2); Taylor, L. (2); Harris, M. (2); Hill, K (2); Sattar, A (2); Burke, J (2); Patel, M (2); Carlsson, S (2); Teo, SH (2); Radice, P (2); Lubinski, J (2); Liljegren, A (2); Thompson, A (2); Potter, A (2); Eccles, D (2); Evans, DG (2); Falconer, A (2); Miller, C (2); Gronberg, H (2); Weissman, S (2); Taylor, A (2); Kote-Jarai, Z (2); Cybulski, C (2); Wokolorczyk, D (2); Maia, S (2); Hamdy, FC (2); Eeles, RA (2); Van As, N (2); Ogden, C (2); Patterson, B (2); Nicolai, N (2); Mercer, C (2); Jacobs, C (2); Moller, P. (2); Strom, S (2); Hjalm-Eriksson, M. (2); Andrews, L (2); Hunt, C (2); Douglas, F (2); visa färre...

Lärosäte: Karolinska Institutet (3); Uppsala universitet (2); Göteborgs universitet (1); Lunds universitet (1)

Språk: Engelska (4)

Forskningsämne (UKÄ/SCB): Medicin och hälsovetenskap (2)

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