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Träfflista för sökning "WFRF:(Chiari M.) "

Sökning: WFRF:(Chiari M.)

  • Resultat 1-10 av 16
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1.
  • Maes, S.L., et al. (författare)
  • Environmental drivers of increased ecosystem respiration in a warming tundra
  • 2024
  • Ingår i: Nature. - : Springer Nature. - 0028-0836 .- 1476-4687. ; 629:8010, s. 105-113
  • Tidskriftsartikel (refereegranskat)abstract
    • Arctic and alpine tundra ecosystems are large reservoirs of organic carbon. Climate warming may stimulate ecosystem respiration and release carbon into the atmosphere. The magnitude and persistency of this stimulation and the environmental mechanisms that drive its variation remain uncertain. This hampers the accuracy of global land carbon–climate feedback projections. Here we synthesize 136 datasets from 56 open-top chamber in situ warming experiments located at 28 arctic and alpine tundra sites which have been running for less than 1 year up to 25 years. We show that a mean rise of 1.4 °C [confidence interval (CI) 0.9–2.0 °C] in air and 0.4 °C [CI 0.2–0.7 °C] in soil temperature results in an increase in growing season ecosystem respiration by 30% [CI 22–38%] (n = 136). Our findings indicate that the stimulation of ecosystem respiration was due to increases in both plant-related and microbial respiration (n = 9) and continued for at least 25 years (n = 136). The magnitude of the warming effects on respiration was driven by variation in warming-induced changes in local soil conditions, that is, changes in total nitrogen concentration and pH and by context-dependent spatial variation in these conditions, in particular total nitrogen concentration and the carbon:nitrogen ratio. Tundra sites with stronger nitrogen limitations and sites in which warming had stimulated plant and microbial nutrient turnover seemed particularly sensitive in their respiration response to warming. The results highlight the importance of local soil conditions and warming-induced changes therein for future climatic impacts on respiration.
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2.
  • Gottardo, A., et al. (författare)
  • New Isomers in the Neutron-Rich Region Beyond 208Pb
  • 2014
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2100-014X. - 9782759811755 - 9782759811762 ; 66, s. 02043-02043
  • Konferensbidrag (refereegranskat)abstract
    • The region of neutron-rich nuclei beyond 208Pb has been very difficult to explore due to its high mass and exoticity. However, recent experimental improvements allowed one to perform a quite extended isomer decay spectroscopy of these nuclei.
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3.
  • Pietralla, N., et al. (författare)
  • On the Road to FAIR: 1st Operation of AGATA in PreSPEC at GSI
  • 2014
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2100-014X. - 9782759811755 - 9782759811762 ; 66, s. 02083-02083
  • Konferensbidrag (refereegranskat)abstract
    • The Facility for Antiproton and Ion Research (FAIR), under construction at Darmstadt will provide intense relativistic beams of exotic nuclei at its Superconducting-FRagment Separator. High-resolution in-beam γ-ray spectroscopy will be performed in the HISPEC experiment, using the European Advanced GAmma-ray Tracking Array (AGATA). The PreSPEC-AGATA campaign is the predecessor of HISPEC and runs from 2012 to 2014 at GSI Helmholtzzentrum für Schwerionenforschung GmbH. Up to19 AGATA modules were used at GSI's F Ragment Separator in 2012. We report on the status of the experiment including preliminary results from performance commissioning.
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4.
  • Forsberg, Ulrika, et al. (författare)
  • Spectroscopic Tools Applied to Element Z = 115 Decay Chains
  • 2014
  • Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2100-014X .- 2101-6275. - 9782759811755 - 9782759811762 ; 66, s. 02036-02036
  • Konferensbidrag (refereegranskat)abstract
    • Nuclides that are considered to be isotopes of element Z = 115 were produced in the reaction 48Ca + 243Am at the GSI Helmholtzzentrum für Schwerionenforschung Darmstadt. The detector setup TASISpec was used. It was mounted behind the gas-filled separator TASCA. Thirty correlated α-decay chains were found, and the energies of the particles were determined with high precision. Two important spectroscopic aspects of the offline data analysis are discussed in detail: the handling of digitized preamplified signals from the silicon strip detectors, and the energy reconstruction of particles escaping to upstream detectors relying on pixel-by-pixel dead-layer thicknesses.
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5.
  • Auer-Grumbach, Michaela, et al. (författare)
  • Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies
  • 2016
  • Ingår i: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 99:3, s. 607-623
  • Tidskriftsartikel (refereegranskat)abstract
    • Axonal polyneuropathies are a frequent cause of progressive disability in the elderly. Common etiologies comprise diabetes mellitus, paraproteinaemia, and inflammatory disorders, but often the underlying causes remain elusive. Late-onset axonal Charcot-Marie-Tooth neuropathy (CMT2) is an autosomal-dominantly inherited condition that manifests in the second half of life and is genetically largely unexplained. We assumed age-dependent penetrance of mutations in a so far unknown gene causing late-onset CMT2. We screened 51 index case subjects with late-onset CMT2 for mutations by whole-exome (WES) and Sanger sequencing and subsequently queried WES repositories for further case subjects carrying mutations in the identified candidate gene. We studied nerve pathology and tissue levels and function of the abnormal protein in order to explore consequences of the mutations. Altogether, we observed heterozygous rare loss-of-function and missense mutations in MME encoding the metalloprotease neprilysin in 19 index case subjects diagnosed with axonal polyneuropathies or neurodegenerative conditions involving the peripheral nervous system. MME mutations segregated in an autosomal-dominant fashion with age-related incomplete penetrance and some affected individuals were isolated case subjects. We also found that MME mutations resulted in strongly decreased tissue availability of neprilysin and impaired enzymatic activity. Although neprilysin is known to degrade beta-amyloid, we observed no increased amyloid deposition or increased incidence of dementia in individuals with MME mutations. Detection of MME mutations is expected to increase the diagnostic yield in late-onset polyneuropathies, and it will be tempting to explore whether substances that can elevate neprilysin activity could be a rational option for treatment.
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7.
  • Carlborg, Carl Fredrik, et al. (författare)
  • Biosticker : patterned microfluidic stickers for rapid integration with microarrays
  • 2011
  • Ingår i: The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS 2011). - : Chemical and Biological Microsystems Society. - 9781618395955 ; , s. 311-313
  • Konferensbidrag (refereegranskat)abstract
    • We present a one-step, reversible, and biocompatible bonding method of a stiff patterned microfluidic "Biosticker", based on off-stoichiometry thiol-ene (OSTE) polymers [1], to state-of-the-art spotted microarray surfaces. The method aims at improving and simplifying the batch back-end processing of microarrays. We illustrate its ease of use in two applications: a high sensitivity flow-through protein assay; and a DNA-hybridization test. Read-out was performed in a standard highvolume array scanner, and showed excellent spot homogeneity and intensity. The Biosticker is aimed to be a plug-in for existing microarray platforms to enable faster protein assays and DNA hybridizations through mass transport optimization.
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9.
  • Carpaneto, Giuseppe M., et al. (författare)
  • Biological and distributional overview of the genus Eledonoprius (Coleoptera: Tenebrionidae)mology : Rare fungus-feeding beetles of European old-growth forests
  • 2013
  • Ingår i: European Journal of Entomology. - 1210-5759 .- 1802-8829. ; 110:1, s. 173-176
  • Tidskriftsartikel (refereegranskat)abstract
    • All the information on the genus Eledonoprius was gathered to provide an up to-date overview of the geographical distribution and ecology of its species, and to assess their association with old-growth forests. Based on recent samples collected in deciduous forests and woodlands of Italy, the authors outline the habitats of these rare species and give an account of their trophic relations with bracket fungi. E. armatus is recorded in Central Italy and Sardinia for the first time; E. serrifrons is new to Basilicata (Southern Italy) and Syria.
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10.
  • Chiari, Stefano, et al. (författare)
  • Monitoring presence, abundance and survival probability of the stag beetle, Lucanus cervus, using visual and odour-based capture methods: implications for conservation
  • 2014
  • Ingår i: Journal of Insect Conservation. - : Springer Science and Business Media LLC. - 1366-638X .- 1572-9753. ; 18:1, s. 99-109
  • Tidskriftsartikel (refereegranskat)abstract
    • A capture-mark-recapture study on the threatened saproxylic beetle Lucanus cervus was carried out in a chestnut (Castanea sativa) woodland located in northern Italy, using visual encounter surveys (VES) as well as aerial flight interception traps and pitfall traps (PT), both of which were baited with different odour lures. In total, 111 males and 25 females were captured, and VES was by far the most efficient method, accounting for 93 % of first captures, and 95 % of all captures. Stag beetles were not significantly attracted to any tested odour, and many PT were damaged by wild boars (Sus scrofa). Flying males were the most frequent adults observed during the season. The use of a net is necessary to capture the stag beetles, in order to evaluate the population parameters and to assess the local status of threat for the species. Capture data revealed that body size (i.e. body weight and elytron length) influences the survival probability of stag beetles, showing a lower survival probability for larger males. Felt-tip pen marking on the ventral sclerites of head and pronotum is a reliable and long lasting method for marking beetles, as proved by the use of an independent marking procedure with a small drill. Assessing the presence and threat status of L. cervus across Europe is urgently needed, and with no efficient odour-based strategy available, collection of adult beetles, dead or alive, by VES is the most reliable way to monitor this emblematic species.
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