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- Lødrup Carlsen, K C, et al.
(författare)
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Assessment of problematic severe asthma in children.
- 2011
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Ingår i: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 37:2, s. 432-40
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Tidskriftsartikel (refereegranskat)abstract
- Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients.
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- Casola, V., et al.
(författare)
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Securing freight trains for hazardous material transportation : A WSN-based monitoring system
- 2012
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Ingår i: International Defense and Homeland Security Simulation Workshop, DHSS 2012, Held at the International Multidisciplinary Modeling and Simulation Multiconference, I3M 2012. - : Caltek s.r.l.. ; , s. 52-59
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Konferensbidrag (refereegranskat)abstract
- In recent years the interest in monitoring infrastructures has spread in many application domains, even because of the number of natural disasters and terrorist attacks. This important activity can be seen in the general context of critical infrastructure protection such as the freight train meant for hazardous materials transportation. The design of these systems must answer to several issues: low-cost, easiness of installation, interoperability of information sources, security mechanisms. The use of wireless sensor networks emerged in this field as a compliant solution to these issues. In this paper we will present a monitoring system that uses heterogeneous WSN to monitor a freight train transporting hazardous materials. The sensors interact through a security platform in order to share different information. We illustrate some details on the architecture and the software application to prove the feasibility of such system on a real scenario by discussing most significant results about measurement parameters and networks performance. Copyright© (2012) by CAL-TEK S.r.l.
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- De Benedictis, A., et al.
(författare)
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Digital Twins for Anomaly Detection in the Industrial Internet of Things : Conceptual Architecture and Proof-of-Concept
- 2023
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Ingår i: IEEE Transactions on Industrial Informatics. - : IEEE Computer Society. - 1551-3203 .- 1941-0050. ; 19:12, s. 11553-11563
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Tidskriftsartikel (refereegranskat)abstract
- Modern cyber-physical systems based on the industrial Internet of Things (IIoT) can be highly distributed and heterogeneous, and that increases the risk of failures due to misbehavior of interconnected components, or other interaction anomalies. In this article, we introduce a conceptual architecture for IIoT anomaly detection based on the paradigms of digital twins (DT) and autonomic computing (AC), and we test it through a proof-of-concept of industrial relevance. The architecture is derived from the current state-of-the-art in DT research and leverages on the MAPE-K feedback loop of AC in order to monitor, analyze, plan, and execute appropriate reconfiguration or mitigation strategies based on the detected deviation from prescriptive behavior stored as shared knowledge. We demonstrate the approach and discuss results by using a reference operational scenario of adequate complexity and criticality within the European Railway Traffic Management System.
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| 6. |
- Bush, A, et al.
(författare)
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Re: A new perspective on concepts of asthma severity and control.
- 2009
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Ingår i: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 33:3, s. 705-6; author reply 706
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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