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Sökning: WFRF:(Höfer T.)

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1.
  • Amiri, M., et al. (författare)
  • Periodic activity from a fast radio burst source
  • 2020
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 582:7812, s. 351-355
  • Tidskriftsartikel (refereegranskat)abstract
    • Fast radio bursts (FRBs) are bright, millisecond-duration radio transients originating from sources at extragalactic distances1, the origin of which is unknown. Some FRB sources emit repeat bursts, ruling out cataclysmic origins for those events2–4. Despite searches for periodicity in repeat burst arrival times on timescales from milliseconds to many days2,5–7, these bursts have hitherto been observed to appear sporadically and—although clustered8—without a regular pattern. Here we report observations of a 16.35 ± 0.15 day periodicity (or possibly a higher-frequency alias of that periodicity) from the repeating FRB 180916.J0158+65 detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst Project4,9. In 38 bursts recorded from 16 September 2018 to 4 February 2020 utc, we find that all bursts arrive in a five-day phase window, and 50 per cent of the bursts arrive in a 0.6-day phase window. Our results suggest a mechanism for periodic modulation either of the burst emission itself or through external amplification or absorption, and disfavour models invoking purely sporadic processes.
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2.
  • Hudson, Lawrence N, et al. (författare)
  • The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
  • 2017
  • Ingår i: Ecology and Evolution. - : John Wiley & Sons. - 2045-7758. ; 7:1, s. 145-188
  • Tidskriftsartikel (refereegranskat)abstract
    • The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
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3.
  • Kleiner, Alexander, et al. (författare)
  • RoboCupRescue - Robot League Team RescueRobots Freiburg (Germany)
  • 2005
  • Ingår i: RoboCup 2005 (CDROM Proceedings), Team Description Paper, Rescue Robot League.
  • Konferensbidrag (refereegranskat)abstract
    • This paper describes the approach of the RescueRobots Freiburg team. RescueRobots Freiburg is a team of students from the university of Freiburg, that originates from the former CS Freiburg team (RoboCupSoccer) and the ResQ Freiburg team (RoboCupRescue Simulation). Due to the high versatility of the RoboCupRescue competition we tackle the three arenas by a a twofold approach: On the one hand we want to introduce robust vehicles that can safely be teleoperated through rubble and building debris while constructing three-dimensional maps of the environment. On the other hand we want to introduce a team of autonomous robots that quickly explore a large terrain while building a two-dimensional map. This two solutions are particularly well-suited for the red and yellow arena, respectively. Our solution for the orange arena will finally be decided between these two, depending on the capabilities of both approaches at the venue. In this paper, we introduce some preliminary results that we achieved so far from map building, localization, and autonomous victim identification. Furthermore we introduce a custom made 3D Laser Range Finder (LRF) and a novel mechanism for the active distribution of RFID tags.
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4.
  • Brandner, Marco, 1900, et al. (författare)
  • High temperature fuel cell, which is an electrochemical energy converter, comprises a ferritic component and a nickel component and an intermediate barrier layer, which consists of e.g. cerium oxide
  • 2006
  • Patent (övrigt vetenskapligt/konstnärligt)abstract
    • TECHNOLOGY FOCUS - INORGANIC CHEMISTRY - Preferred Components: The barrier layer consists of cerium dioxide. The barrier layer is endowed with yttrium, gadolinium, niobium or samarium. The barrier layer covers at least on one side of the ferritic component, as thin, preferably thick film. The barrier layer is not thicker than 10 mu m, preferably thinner than 2 mu m. The ferritic component is a porous metallic substrate and the nickel component is an anode. The ferritic component is an inter-connector and the nickel component is a nickel network. The barrier layer consists of: (calcium, strontium, barium)1-3x/2 (yttrium, lanthanide (ln))x titanium oxide (where Xy is 0-0.1 and/or Xln is 0-0.67); chromium oxide and/or chromium(II, III) oxide, manganese(II, III) oxide; iron(II) oxide and/or iron(II, III) oxide; cerium1-x-y (yttrium, lanthanide)x (titanium, niobium)yO2 (where x is 0-0.5 and y is 0-0.2); lanthanide1-x(strontium, calcium)x (magnesium oxide (mgO3)) aluminum oxide (AlO3), chromium oxide (CrO3) (where x is 0.1-0.5).
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5.
  • Cvijovic, Marija, 1977, et al. (författare)
  • Strategies for structuring interdisciplinary education in systems biology: An European perspective
  • 2016
  • Ingår i: npj Systems Biology and Applications. - : Springer Science and Business Media LLC. - 2056-7189. ; 2
  • Tidskriftsartikel (refereegranskat)abstract
    • Systems Biology is an approach to biology and medicine that has the potential to lead to a better understanding of how biological properties emerge from the interaction of genes, proteins, molecules, cells and organisms. The approach aims at elucidating how these interactions govern biological function by employing experimental data, mathematical models and computational simulations. As Systems Biology is inherently multidisciplinary, education within this field meets numerous hurdles including departmental barriers, availability of all required expertise locally, appropriate teaching material and example curricula. As university education at the Bachelor’s level is traditionally built upon disciplinary degrees, we believe that the most effective way to implement education in Systems Biology would be at the Master’s level, as it offers a more flexible framework. Our team of experts and active performers of Systems Biology education suggest here (i) a definition of the skills that students should acquire within a Master’s programme in Systems Biology, (ii) a possible basic educational curriculum with flexibility to adjust to different application areas and local research strengths, (iii) a description of possible career paths for students who undergo such an education, (iv) conditions that should improve the recruitment of students to such programmes and (v) mechanisms for collaboration and excellence spreading among education professionals. With the growing interest of industry in applying Systems Biology approaches in their fields, a concerted action between academia and industry is needed to build this expertise. Here we present a reflection of the European situation and expertise, where most of the challenges we discuss are universal, anticipating that our suggestions will be useful internationally. We believe that one of the overriding goals of any Systems Biology education should be a student’s ability to phrase and communicate research questions in such a manner that they can be solved by the integration of experiments and modelling, as well as to communicate and collaborate productively across different experimental and theoretical disciplines in research and development.
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6.
  • Takahashi, M., et al. (författare)
  • Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics
  • 2021
  • Ingår i: Stem Cell Reports. - : Elsevier BV. - 2213-6711. ; 16:4, s. 741-753
  • Tidskriftsartikel (refereegranskat)abstract
    • Hematopoiesis serves as a paradigm for how homeostasis is maintained within hierarchically organized cell populations. However, important questions remain as to the contribution of hematopoietic stem cells (HSCs) toward maintaining steady state hematopoiesis. A number of in vivo lineage labeling and propagation studies have given rise to contradictory interpretations, leaving key properties of stem cell function unresolved. Using processed flow cytometry data coupled with a biology-driven modeling approach, we show that in vivo flux experiments that come from different laboratories can all be reconciled into a single unifying model, even though they had previously been interpreted as being contradictory. We infer from comparative analysis that different transgenic models display distinct labeling efficiencies across a heterogeneous HSC pool, which we validate by marker gene expression associated with HSC function. Finally, we show how the unified model of HSC differentiation can be used to simulate clonal expansion in the early stages of leukemogenesis. © 2021 The Authors
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