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| 2. |
- Karlsson, Ann-Katrine, 1950, et al.
(författare)
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Abdominal fat distribution correlates to aromatase activity in pre-school girls
- 2013
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Ingår i: 9th Joint Meeting of Paediatric Endocrinology. Milan, Italy , September 19–22, 2013. Hormone research in paediatrics. - Milan, Italy : Horm Res in Ped. - 1663-2818 .- 1663-2826. ; 80:suppl 1, s. 109-110
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 3. |
- Karlsson, Ann-Katrine, 1950, et al.
(författare)
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Measurements of total and regional body composition in preschool children: A comparison of MRI, DXA, and anthropometric data.
- 2013
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Ingår i: Obesity (Silver Spring, Md.). - : Wiley. - 1930-739X .- 1930-7381. ; 21:5, s. 1018-24
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Tidskriftsartikel (refereegranskat)abstract
- There are clear sex differences in the distribution of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in adults, with males having more VAT and less SAT than females. This study assessed whether these differences between the sexes were already present in preschool children. It also evaluated which measures of body composition were most appropriate for assessing abdominal obesity in this age group.
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| 4. |
- Kullberg, Joel, et al.
(författare)
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Adipose tissue distribution in children: automated quantification using water and fat MRI.
- 2010
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Ingår i: Journal of magnetic resonance imaging : JMRI. - : Wiley. - 1522-2586 .- 1053-1807. ; 32:1, s. 204-10
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To develop and validate a method for rapid acquisition and automated processing of magnetic resonance (MR) images for analysis of abdominal adipose tissue distribution in children. Materials and Methods: The study included 21 (10 girls, 11 boys) healthy 5-year-old children. Rapid water and fat MR imaging (6 sec) was performed using a 2-point-Dixon technique on a 1.5T MR scanner using an 8-channel cardiac coil. An automated image processing algorithm was developed for automated segmentation of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), respectively. The results from the fully automated analysis were compared to those from a semiautomated analysis, performed by three operators, from the same images. Results: The automated analysis was seen to give results with strong correlation to the reference measurements (r ≥ 0.997); however, the SAT volume was underestimated by 9.4 ± 3.8%. The accuracy of the automated segmentation of VAT and SAT (TP: true positive, FP: false positive, mean ± SD, %) was TP: 83.6 ± 8.5, FP: 12.7 ± 6.8; and TP: 89.9 ± 3.6, FP: 0.7 ± 0.3, respectively.
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| 5. |
- Kvernebo-Sunnergren, Kjersti, 1974, et al.
(författare)
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Adrenal androgen trajectories are established during childhood in preterm boys
- 2021
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 110:11, s. 3116-3123
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Tidskriftsartikel (refereegranskat)abstract
- Aim We investigated longitudinal adrenal androgen concentrations and any relationship between gestational age, birth size, anthropometric parameters and adrenal androgen concentrations during childhood in boys born moderate to late preterm. Methods This longitudinal, prospective study included 58 boys born at 32+0 to 36+6 weeks of gestation. Dehydroepiandrosterone sulphate and androstenedione were analysed by liquid chromatography-tandem mass spectrometry, and anthropometric data were recorded from 5 to 10 years of age. Results Dehydroepiandrosterone sulphate concentrations correlated with weight standard deviations scores (SDS) from 7 to 10 years of age and waist-to-height ratios at seven and 10 years of age. Androstenedione correlated with weight SDS from 7 to 10 years of age and waist-to-height ratios at 10 years of age. Longitudinal analysis showed a relationship between weight SDS and waist-to-height SDS and dehydroepiandrosterone sulphate (p p < 0.001, respectively) and androstenedione (p = 0.002 and p = 0.003, respectively), independently of age. Conclusion The trajectories of anthropometric parameters and adrenal androgen secretion were consistent from 5 to 10 years of age in this cohort. The body composition reflected by current weight and the waist-to-height ratio, rather than gestational age and birth size, was associated with adrenal androgen secretion.
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| 6. |
- Kvernebo-Sunnergren, Kjersti, 1974, et al.
(författare)
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Pre- and peripubertal sex steroids are inversely associated with birth weight in preterm boys
- 2022
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Ingår i: Clinical Endocrinology. - : Wiley. - 0300-0664 .- 1365-2265.
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Tidskriftsartikel (refereegranskat)abstract
- Objective The relationship between sex hormone concentrations during childhood and birth weight (BW) is poorly understood. We aimed to investigate this relationship and the associations with anthropometric data at 5, 6, 7, 8, and 10 years of age in preterm boys. Design A prospective longitudinal single-centre study, including 58 boys with a BW of 1325-3320 g and gestational age (GA) of 32 + 2 to 36 + 6 weeks. Patients and Measurements Data on GA, BW and anthropometric data between 5 and 10 years of age were recorded. Testicular development was assessed at 8 and 10 years of age. Serum concentrations of sex steroids were analysed with gas chromatography-tandem mass spectrometry at 5-10 years and luteinizing hormone (LH) and follicle-stimulating hormone (FSH) with immunoassays at 10 years of age. Results At 8 years of age, testosterone and estrone correlated negatively with BW, (rho = -0.35, p = .021) and (rho = -0.34, p = .024), respectively. At 10 years of age, testosterone, dihydrotestosterone, estrone and estradiol correlated negatively with BW (rho = -0.39, p = .010), (rho = -0.38, p = .013), (rho = -0.44, p = .003) and (rho = -0.36, p = .019), respectively. Weight gain from birth correlated with testosterone at 5 years (rho = 0.40, p = .002), 7 years (rho = 0.30, p = .040), 8 years (rho = 0.44, p = .003) and 10 years (rho = 0.40, p = .008) of age. At 10 years of age, testosterone correlated with LH (rho = 0.42, p = .006) and FSH (rho = 0.33, p = .033) but not with testicular volume. Conclusions Lower BW was associated with increased sex steroid concentrations from 8 years of age, independently of clinical signs of puberty.
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| 7. |
- Nilsson, Josefin, 1973, et al.
(författare)
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Normal visual evoked potentials in preschool children born small for gestational age.
- 2011
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Ingår i: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 1651-2227 .- 0803-5253. ; 100:8, s. 1092-6
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Tidskriftsartikel (refereegranskat)abstract
- Previous studies have shown visual evoked potential (VEP) abnormalities in infants and animals born small for gestational age (SGA) compared with controls. The current exploratory study aims to investigate whether VEP abnormalities persist in older ages.
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