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1.
  • Klingström, Tomas, et al. (författare)
  • Supporting the Development of Biobanks in Low and Medium Income Countries
  • 2016
  • Ingår i: 2016 IST-AFRICA WEEK CONFERENCE. - 9781905824557
  • Konferensbidrag (refereegranskat)abstract
    • Biobanks are an organized collection of biological material and associated data. They are a fundamental resource for life science research and contribute to the development of pharmaceutical drugs, diagnostic markers and to a deeper understanding of the genetics that regulate the development of all life on earth. Biobanks are well established in High Income Countries (HIC) and are rapidly emerging in Low and Middle Income Countries (LMIC). Surveys among biobanks operating in a LMIC setting indicate that limited resources and short term funding tied to specific projects threaten the sustainability of the biobanks. Fit-for-purpose biobanks targeting major societal challenges such as HIV and Malaria provide an excellent basis for integrating biobanks with the available research communities in LMIC regions. But to become sustainable for the future it is important that biobanks become an integrated part of local research communities. To achieve this, the cost of operating biobanks must be lowered, templates must be developed to support local ethics committees and researchers must be given the opportunity to build experience in successfully operating biobank based research projects. The B3Africa consortium is based on these conclusions and set up to support biobank based research by creating a cost efficient Laboratory Information Management System (LIMS) for developing biobanks and also contribute to the training and capacity building in the local research community. The technical platform called the eB3Kit is open source and consists of a LIMS and a bioinformatics module based on the eBiokit that allow researchers to take control over the analysis of their own data. Along with the technical platform the consortium will also contribute training and support for the associated infrastructures necessary to regulate the ethical and legal implications of biobank based research.
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2.
  • Polpanich, Orn-Uma, et al. (författare)
  • Modelling impacts of development on water resources in the Huai Sai Bat sub-basin in north-eastern Thailand with a participatory approach
  • 2017
  • Ingår i: International Journal of Water Resources Development. - : Informa UK Limited. - 0790-0627 .- 1360-0648. ; 33:6, s. 1020-1040
  • Tidskriftsartikel (refereegranskat)abstract
    • Little is done to connect hydrological modelling with stakeholder participation. This study incorporates agricultural development and climatic changes within the Water Evaluation and Planning hydrological model. This is done with a participatory approach involving four scenario workshops, 400 household surveys and two focus group discussions in the period of 2010-2012 for the ungauged Huai Sai Bat sub-basin as a case study in the Mekong region. The modelling results indicate future increased streamflow during the wet (monsoon) season in response to shifts in the regional climate. Modelled land-use and management changes brought about large unmet water demands, primarily in the dry season.
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