| 1. |
- Hongisto, Valtteri, et al.
(författare)
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Sound insulation dataset of 30 wooden and 8 concrete floors tested in laboratory conditions
- 2023
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Ingår i: Data in Brief. - : Elsevier Inc.. - 2352-3409. ; 49
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Tidskriftsartikel (refereegranskat)abstract
- In a Finnish-Swedish consortium project, a large amount of sound insulation tests was conducted for several intermediate floors in laboratory conditions to serve various scientific research questions. The dataset contains 30 wooden and 8 concrete constructions which are commonly used between apartments in multistorey buildings. Impact sound insulation was determined according to ISO 10140-3 standard using both tapping machine and rubber ball as standard sound sources. Airborne sound insulation was determined according to the ISO 10140-2 standard. The data are special since they have a broad frequency range: 20−5000 Hz. Data are reported in 1/3-octave frequency bands and the single-number values of ISO 717-1 and ISO 717-2 are also reported. Detailed construction drawings are available for all reported constructions. The data are highly valuable for research, education, and development purposes since all data were obtained in the same laboratory (Turku University of Applied Sciences, Turku, Finland), and all the constructions were built by the same installation team. © 2023 The Authors
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| 2. |
- Peltola, J, et al.
(författare)
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Interleukin-6 and interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures.
- 2000
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Ingår i: Epilepsy Res. - Tampere Univ Hosp, Dept Neurol, FIN-33101 Tampere, Finland. Tampere Univ Hosp, Dept Clin Microbiol, FIN-33101 Tampere, Finland. Univ Tampere, Sch Med, FIN-33101 Tampere, Finland. Dept Neurosci, Uppsala, Sweden. : ELSEVIER SCIENCE BV. - 0920-1211 .- 1872-6844. ; 41:3, s. 205-11
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Tidskriftsartikel (refereegranskat)
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| 3. |
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| 4. |
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| 5. |
- Balasubramanian, V., et al.
(författare)
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Thermalization of the spectral function in strongly coupled two dimensional conformal field theories
- 2013
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Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; 4, s. 069-
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Tidskriftsartikel (refereegranskat)abstract
- Using Wigner transforms of Green functions, we discuss non-equilibrium generalizations of spectral functions and occupation numbers. We develop methods for computing time-dependent spectral functions in conformal field theories holographically dual to thin-shell AdS-Vaidya spacetimes.
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| 6. |
- Durrant, Jacob D., et al.
(författare)
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Computational Identification of Uncharacterized Cruzain Binding Sites
- 2010
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Ingår i: PLoS Neglected Tropical Diseases. - : Public Library of Science (PLoS). - 1935-2727 .- 1935-2735. ; 4:5, s. e676-
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Tidskriftsartikel (refereegranskat)abstract
- Chagas disease, caused by the unicellular parasite Trypanosoma cruzi, claims 50,000 lives annually and is the leading cause of infectious myocarditis in the world. As current antichagastic therapies like nifurtimox and benznidazole are highly toxic, ineffective at parasite eradication, and subject to increasing resistance, novel therapeutics are urgently needed. Cruzain, the major cysteine protease of Trypanosoma cruzi, is one attractive drug target. In the current work, molecular dynamics simulations and a sequence alignment of a non-redundant, unbiased set of peptidase C1 family members are used to identify uncharacterized cruzain binding sites. The two sites identified may serve as targets for future pharmacological intervention.
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| 7. |
- Rogers, Kathleen E., et al.
(författare)
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Novel Cruzain Inhibitors for the Treatment of Chagas' Disease
- 2012
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Ingår i: Chemical Biology and Drug Design. - : Wiley. - 1747-0277 .- 1747-0285. ; 80:3, s. 398-405
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Tidskriftsartikel (refereegranskat)abstract
- The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas disease, affects millions of individuals and continues to be an important global health concern. The poor efficacy and unfavorable side effects of current treatments necessitate novel therapeutics. Cruzain, the major cysteine protease of T.similar to cruzi, is one potential novel target. Recent advances in a class of vinyl sulfone inhibitors are encouraging; however, as most potential therapeutics fail in clinical trials and both disease progression and resistance call for combination therapy with several drugs, the identification of additional classes of inhibitory molecules is essential. Using an exhaustive virtual-screening and experimental validation approach, we identify several additional small-molecule cruzain inhibitors. Further optimization of these chemical scaffolds could lead to the development of novel drugs useful in the treatment of Chagas disease.
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| 8. |
- Sterner, Jan, et al.
(författare)
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Sulfurization of thin film solar cell absorbers
- 2000
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Ingår i: Sixteent h European Photovoltaic Solar Energy Conference and Exhibition, Glasgow, May 1-5. ; , s. 771-774
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Konferensbidrag (refereegranskat)
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