| 1. |
- Hebbeln, Dierk, et al.
(författare)
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Late Holocene coastal hydrographic and climate changes in the eastern North Sea
- 2006
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Ingår i: The Holocene. - : SAGE Publications. - 0959-6836 .- 1477-0911. ; 16:7, s. 987-1001
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Tidskriftsartikel (refereegranskat)abstract
- We present a high-resolution palaeoenvironmental reconstruction covering the late Holocene from the Skagerrak and other sites in the North Sea area. The data, which are based on the analyses of marine sediment cores, reveal a marked environmental shift that took place between AD 700 and AD 1100, with the most pronounced changes occurring at AD 900. Both surface and bottom waters in the Skagerrak were subject to major circulation and productivity changes at this time due to an enhanced advection of Atlantic waters to the North Sea marking the beginning of the 'Mediaeval Warm Period' (MWP). The observed increase in bottom current strength is especially remarkable as there is hardly any comparable signal in the older part of the record going back to 1000 BC. At the transition to the 'Little Ice Age' (LIA) the bottom current strength remains at a high level, now probably forced by atmospheric circulation. Thus, despite opposite temperature forcing, these two consecutive climate scenarios are apparently able to generate distinctly stronger bottom currents in the Skagerrak than observed in the preceding 2000 years, and demonstrate the significance of climatic forcing in shaping the marine environment. Indeed, both the MWP and the LIA are reported as strong climatic signals in northwest Europe, being the warmest (except the late twentieth century) and coldest periods, respectively, during at least the last 2000 years.
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| 2. |
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| 3. |
- Metcalfe, Daniel B., et al.
(författare)
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Ecological stoichiometry and nutrient partitioning in two insect herbivores responsible for large-scale forest disturbance in the Fennoscandian subarctic
- 2019
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Ingår i: Ecological Entomology. - : Wiley. - 0307-6946 .- 1365-2311. ; 44:1, s. 118-128
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Tidskriftsartikel (refereegranskat)abstract
- 1. Outbreaks of herbivorous insects can have large impacts on regional soil carbon (C) storage and nutrient cycling. In northernmost Europe, population outbreaks of several geometrid moth species regularly cause large-scale defoliation in subarctic birch forests. An improved understanding is required of how leaf C and nutrients are processed after ingestion by herbivores and what this means for the quantity and quality of different materials produced (frass, bodies). 2. In this study, larvae of two geometrid species responsible for major outbreaks (Epirrita autumnata and Operophtera brumata) were raised on exclusive diets of Betula pubescens var. czerepanovii (N. I. Orlova) Hämet Ahti and two other abundant understorey species (Betula nana, Vaccinium myrtillus). The quantities of C, nitrogen (N) and phosphorus (P) ingested and allocated to frass, bodies and (in the case of C) respired were recorded. 3. Overall, 23%, 70% and 48% of ingested C, N and P were allocated to bodies, respectively, rather than frass and (in the case of C) respiration. Operophtera brumata consistently maintained more constant body stoichiometric ratios of C, N and P than did E. autumnata, across the wide variation in physico-chemical properties of plant diet supplied. 4. These observed differences and similarities on C and nutrient processing may improve researchers' ability to predict the amount and stoichiometry of frass and bodies generated after geometrid outbreaks.
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| 4. |
- Pearce, Neil E, et al.
(författare)
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IARC Monographs : 40 Years of Evaluating Carcinogenic Hazards to Humans
- 2015
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Ingår i: Journal of Environmental Health Perspectives. - : Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 123:6, s. 507-514
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Recently the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also the approach used to perform these evaluations. Some critics have claimed that IARC Working Groups' failures to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans.OBJECTIVES: The authors of this paper are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We have examined here criticisms of the IARC classification process to determine the validity of these concerns. We review the history of IARC evaluations and describe how the IARC evaluations are performed.DISCUSSION: We conclude that these recent criticisms are unconvincing. The procedures employed by IARC to assemble Working Groups of scientists from the various discipline and the techniques followed to review the literature and perform hazard assessment of various agents provide a balanced evaluation and an appropriate indication of the weight of the evidence. Some disagreement by individual scientists to some evaluations is not evidence of process failure. The review process has been modified over time and will undoubtedly be altered in the future to improve the process. Any process can in theory be improved, and we would support continued review and improvement of the IARC processes. This does not mean, however, that the current procedures are flawed.CONCLUSIONS: The IARC Monographs have made, and continue to make, major contributions to the scientific underpinning for societal actions to improve the public's health.
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| 5. |
- Toussaint, Laura, et al.
(författare)
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Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma
- 2022
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Ingår i: Acta Oncologica. - : Informa UK Limited. - 0284-186X .- 1651-226X. ; 61:2, s. 235-238
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Tidskriftsartikel (refereegranskat)abstract
- Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.
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