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1.	de Rojas, I., et al. (författare) Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores 2021 Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1 Tidskriftsartikel (refereegranskat)abstract Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical trials. We first perform a large genetic association study by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190). Here, we add six variants associated with Alzheimer’s disease risk (near APP, CHRNE, PRKD3/NDUFAF7, PLCG2 and two exonic variants in the SHARPIN gene). Assessment of the polygenic risk score and stratifying by APOE reveal a 4 to 5.5 years difference in median age at onset of Alzheimer’s disease patients in APOE ɛ4 carriers. Because of this study, the underlying mechanisms of APP can be studied to refine the amyloid cascade and the polygenic risk score provides a tool to select individuals at high risk of Alzheimer’s disease. © 2021, The Author(s).
2.	Scirica, BM, et al. (författare) Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus 2013 Ingår i: The New England journal of medicine. - 1533-4406. ; 369:14, s. 1317-1326 Tidskriftsartikel (refereegranskat)
3.	Salmanton-García, J, et al. (författare) Decoding the historical tale: COVID-19 impact on haematological malignancy patients-EPICOVIDEHA insights from 2020 to 2022 2024 Ingår i: EClinicalMedicine. - 2589-5370. ; 71, s. 102553- Tidskriftsartikel (refereegranskat)
4.	Chatzikonstantinou, T, et al. (författare) COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study 2021 Ingår i: Leukemia. - : Springer Science and Business Media LLC. - 1476-5551 .- 0887-6924. ; 35:12, s. 3444-3454 Tidskriftsartikel (refereegranskat)abstract Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and elucidate the impact of CLL-directed treatments on the course of COVID-19. We conducted a retrospective, international study, collectively including 941 patients with CLL and confirmed COVID-19. Data from the beginning of the pandemic until March 16, 2021, were collected from 91 centers. The risk factors of case fatality rate (CFR), disease severity, and overall survival (OS) were investigated. OS analysis was restricted to patients with severe COVID-19 (definition: hospitalization with need of oxygen or admission into an intensive care unit). CFR in patients with severe COVID-19 was 38.4%. OS was inferior for patients in all treatment categories compared to untreated (p < 0.001). Untreated patients had a lower risk of death (HR = 0.54, 95% CI:0.41–0.72). The risk of death was higher for older patients and those suffering from cardiac failure (HR = 1.03, 95% CI:1.02–1.04; HR = 1.79, 95% CI:1.04–3.07, respectively). Age, CLL-directed treatment, and cardiac failure were significant risk factors of OS. Untreated patients had a better chance of survival than those on treatment or recently treated.
5.	Lahmer, T, et al. (författare) Need for ICU and outcome of critically ill patients with COVID-19 and haematological malignancies: results from the EPICOVIDEHA survey 2024 Ingår i: Infection. - 1439-0973. Tidskriftsartikel (refereegranskat)
6.	Aiello, TF, et al. (författare) Dexamethasone treatment for COVID-19 is related to increased mortality in hematologic malignancy patients: results from the EPICOVIDEHA Registry 2024 Ingår i: Haematologica. - 1592-8721. Tidskriftsartikel (refereegranskat)
7.	Rossi, G, et al. (författare) Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings 2023 Ingår i: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. - 1878-3511. ; 137, s. 98-110 Tidskriftsartikel (refereegranskat)
8.	Musto, P, et al. (författare) Survival in multiple myeloma and SARS-COV-2 infection through the COVID-19 pandemic: Results from the EPICOVIDEHA registry 2024 Ingår i: Hematological oncology. - 1099-1069. ; 42:1, s. e3240- Tidskriftsartikel (refereegranskat)
9.	Salmanton-García, J, et al. (författare) Molnupiravir compared to nirmatrelvir/ritonavir for COVID-19 in high-risk patients with haematological malignancy in Europe. A matched-paired analysis from the EPICOVIDEHA registry 2023 Ingår i: International journal of antimicrobial agents. - 1872-7913. ; 62:4, s. 106952- Tidskriftsartikel (refereegranskat)
10.	Benschop, KSM, et al. (författare) Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021 2021 Ingår i: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. - 1560-7917. ; 26:45 Tidskriftsartikel (refereegranskat)

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Typ av publikation: tidskriftsartikel (22); konferensbidrag (4); forskningsöversikt (2); bokkapitel (1)

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Författare/redaktör: Labrador, J (10); Marchetti, M. (9); Lopez-Garcia, A (9); Cordoba, R (9); Pagano, L. (8); Salmanton-Garcia, J (8); visa fler...; Marchesi, F (8); Weinbergerova, B (8); Farina, F (8); Davila-Valls, J (8); Martin-Perez, S (8); El-Ashwah, S (8); Buquicchio, C (8); Espigado, I (8); Blennow, O (8); Itri, F (8); Meers, S (8); Nordlander, A (8); Arellano, E (8); Glenthoj, A (7); Van Praet, J (7); Falces-Romero, I (7); Vena, A (7); Petzer, V (7); Van Doesum, J (7); Bilgin, YM (7); Dargenio, M (7); Prezioso, L (7); Čolović, N (7); Besson, C (7); Del Principe, MI (7); Jaksic, O (7); Cattaneo, C (7); Mendez, GA (7); Emarah, Z (7); Ammatuna, E (7); Wolf, D (7); Jimenez, M. (6); Sili, U (6); Biernat, MM (6); Tascini, C (6); Valković, T (6); Fracchiolla, NS (6); Demirkan, F (6); Merelli, M (6); Da Silva, MG (6); Hanakova, M (6); Račil, Z (6); Rodrigues, RN (6); Limongelli, A (6); visa färre...

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