| 1. |
- Abdoullaye, Doukary, et al.
(författare)
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Permanent genetic resources added to molecular ecology resources database 1 August 2009 - 30 September 2009
- 2010
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Ingår i: Molecular Ecology Resources. - : Wiley. - 1755-098X .- 1755-0998. ; 10:1, s. 232-236
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Tidskriftsartikel (refereegranskat)abstract
- This article documents the addition of 238 microsatellite marker loci and 72 pairs of Single Nucleotide Polymorphism (SNP) sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Adelges tsugae, Artemisia tridentata, Astroides calycularis, Azorella selago, Botryllus schlosseri, Botrylloides violaceus, Cardiocrinum cordatum var. glehnii, Campylopterus curvipennis, Colocasia esculenta, Cynomys ludovicianus, Cynomys leucurus, Cynomys gunnisoni, Epinephelus coioides, Eunicella singularis, Gammarus pulex, Homoeosoma nebulella, Hyla squirella, Lateolabrax japonicus, Mastomys erythroleucus, Pararge aegeria, Pardosa sierra, Phoenicopterus ruber ruber and Silene latifolia. These loci were cross-tested on the following species: Adelges abietis, Adelges cooleyi, Adelges piceae, Pineus pini, Pineus strobi, Tubastrea micrantha, three other Tubastrea species, Botrylloides fuscus, Botrylloides simodensis, Campylopterus hemileucurus, Campylopterus rufus, Campylopterus largipennis, Campylopterus villaviscensio, Phaethornis longuemareus, Florisuga mellivora, Lampornis amethystinus, Amazilia cyanocephala, Archilochus colubris, Epinephelus lanceolatus, Epinephelus fuscoguttatus, Symbiodinium temperate-A clade, Gammarus fossarum, Gammarus roeselii, Dikerogammarus villosus and Limnomysis benedeni. This article also documents the addition of 72 sequencing primer pairs and 52 allele specific primers for Neophocaena phocaenoides.
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| 2. |
- Miehe, Georg, et al.
(författare)
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The Kobresia pygmaea ecosystem of the Tibetan highlands – Origin, functioning and degradation of the world's largest pastoral alpine ecosystem: Kobresia pastures of Tibet
- 2019
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Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697. ; 648, s. 754-771
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Tidskriftsartikel (refereegranskat)abstract
- With 450,000 km2 Kobresia (syn. Carex) pygmaea dominated pastures in the eastern Tibetan highlands are the world's largest pastoral alpine ecosystem forming a durable turf cover at 3000–6000 m a.s.l. Kobresia's resilience and competitiveness is based on dwarf habit, predominantly below-ground allocation of photo assimilates, mixture of seed production and clonal growth, and high genetic diversity. Kobresia growth is co-limited by livestock-mediated nutrient withdrawal and, in the drier parts of the plateau, low rainfall during the short and cold growing season. Overstocking has caused pasture degradation and soil deterioration over most parts of the Tibetan highlands and is the basis for this man-made ecosystem. Natural autocyclic processes of turf destruction and soil erosion are initiated through polygonal turf cover cracking, and accelerated by soil-dwelling endemic small mammals in the absence of predators. The major consequences of vegetation cover deterioration include the release of large amounts of C, earlier diurnal formation of clouds, and decreased surface temperatures. These effects decrease the recovery potential of Kobresia pastures and make them more vulnerable to anthropogenic pressure and climate change. Traditional migratory rangeland management was sustainable over millennia, and possibly still offers the best strategy to conserve and possibly increase C stocks in the Kobresia turf.
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| 3. |
- Chandrasekaran, Sundaram, et al.
(författare)
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Advanced opportunities and insights on the influence of nitrogen incorporation on the physico-/electro-chemical properties of robust electrocatalysts for electrocatalytic energy conversion
- 2021
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Ingår i: Coordination chemistry reviews. - : Elsevier. - 0010-8545 .- 1873-3840. ; 449
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Forskningsöversikt (refereegranskat)abstract
- The use of a wide range of methods for incorporating nitrogen atoms on robust catalysts has given rise to fundamental advances in the field of energy conversion and storage. Recently, nitrogen incorporation has proven to be able to fine-tune the electron densities of exposed active sites to create high-performance electrocatalysts. The preservation of a strong interface between the local atomic coordination of nitrogen atoms on bare carbon, single metal atoms, transition metal oxides, metal chalcogenides, and MXenes during synthesis plays an important role in producing an efficient electrocatalysts. In addition, the ability of nitrogen atoms to bind with carbon or metal atoms can be influenced by processing conditions. In this regard, this review is the first comprehensive overview of the range of synthetic strategies to form nitrogen incorporated catalysts and assess their chemical, structural, physical electronic property modification and their influence on electrocatalytic ORR, OER, and HER performance. This review will describe how specific strategies have been utilized to realise effective electrocatalytic systems, including the energy conversion of nitrogen incorporated catalysts, structural coordination, and material optimization. Finally, the main challenges to be considered in future investigations in order to initiate new research efforts in this promising research area are discussed.
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| 4. |
- Pour Khavari, Ali, et al.
(författare)
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Serum 8-Oxo-dG as a Predictor of Sensitivity and Outcome of Radiotherapy and Chemotherapy of Upper Gastrointestinal Tumours
- 2018
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Ingår i: Oxidative Medicine and Cellular Longevity. - : Hindawi Limited. - 1942-0900 .- 1942-0994. ; 2018
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Tidskriftsartikel (refereegranskat)abstract
- The level of oxidative stress is important in the initiation and progression of various age-related diseases, such as cancer. The level of oxidative stress may also play a significant role in cancer patients' response to treatment. We aimed to investigate whether serum 8-oxo-dG as a marker of oxidative stress is a predictor of tumour response. We used modified ELISA with a two-step filtration to analyse 8-oxo-dG in serum. The relationship between 8-oxo-dG levels, tumour response, and toxicity was studied in 19 oesophageal cancer patients who received radiotherapy and 16 gastric cancer patients who received chemotherapy. In the radiotherapy and the merged radio-and chemotherapy groups, the baseline levels of 8-oxo-dG were significantly lower in responder patients than in nonresponder patients and the increments after treatment were greater. In comparison with patients whose serum 8-oxo-dG levels decrease after treatment, patients with increasing levels had a longer median progression-free survival. Our results, although preliminary, suggest that serum levels of 8-oxo-dG may potentially be used to predict the sensitivity and outcome of radiotherapy and chemotherapy of upper gastrointestinal tumours. Patients with 8-oxo-dG levels that are low prior to treatment and subsequently increase after treatment may be more likely to benefit from the therapy.
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| 5. |
- Qin, Yingyi, et al.
(författare)
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Comparison and trend of perioperative outcomes between robot-assisted radical prostatectomy and open radical prostatectomy : nationwide inpatient sample 2009-2014
- 2020
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Ingår i: International Brazilian Journal of Urology. - : Sociedade Brasileira de Urologia. - 1677-5538 .- 1677-6119. ; 46:5, s. 754-771
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To make a further evaluation of perioperative outcomes between the robot-assisted radical prostatectomy (RARP) and open radical prostatectomy (ORP), we conducted a comparison and trend analysis by using the Nationwide Inpatient Sample (NIS) from 2009 to 2014.Materials and Methods: Adult prostate cancer patients with radical prostatectomy were abstracted from the NIS. RARP and ORP were identified according to the International Classification of Diseases, 9th Revision, Clinical Modification procedure codes. The perioperative outcomes included blood transfusion, intraoperative and postoperative complications, prolonged length of stay (pLOS), and in-hospital mortality. Propensity score matching method and multivariable logistic regression model were performed to adjust for the pre-defined covariates. The annual percent change (APC) was used to detect the change trend of rates for outcomes.Results: A total of 77.054 patients were included in our study. According to the results of propensity score matching analyses, RARP outperformed ORP in blood transfusion (1.96% vs. 9.40%), intraoperative complication (0.73% vs. 1.25%), overall postoperative complications (8.87% vs. 11.97%), and pLOS (13.39% vs. 36.70%). We also found that there was a significant decreasing tendency of incidence in blood transfusion (APC=-9.81), intraoperative complication (APC=-12.84), and miscellaneous surgical complications (APC=-14.09) for the RARP group. The results of multivariable analyses were almost consistent with those of propensity score matching analyses.Conclusions: The RARP approach has lower incidence rates of perioperative complications than the ORP approach, and there is a potential decreasing tendency of complication incidence rates for the RARP.
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| 6. |
- Zhang, Yongping, et al.
(författare)
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Consensus aware manufacturing service collaboration optimization under blockchain based Industrial Internet platform
- 2019
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Ingår i: Computers & industrial engineering. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0360-8352 .- 1879-0550. ; 135, s. 1025-1035
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Tidskriftsartikel (refereegranskat)abstract
- To realize collaboration among distributed enterprises, manufacturing service collaboration on Industrial Internet platform is an efficient method. However, the low degree of participation resulted by the sense of distrust, dissatisfaction, and insecurity hinders the widely application of Industrial Internet platform. Therefore, a secure, trustworthy, and multi-user satisfied manufacturing service collaboration method is in urgent need. A blockchain based platform could be utilized to support collaboration among distributed participants to complete trustworthy transactions. In addition, in order to satisfy multiple users, there should be a suitable collaboration mechanism that allows interest-independent participants to fulfil their short/long-term expectations and guide them to a consensus. Based on the establishment of the underlying data and network layer of the blockchain, the collaboration optimization of manufacturing services based on consensus is proposed. By utilizing Memetic algorithm, both the long-term utility of providers and the short-term utility of consumers are combined to choose the optimal providers for the tasks. The providers are selected with higher satisfaction degree of consumers.
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| 7. |
- Zhang, Yongping, et al.
(författare)
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Long/short-term utility aware optimal selection of manufacturing service composition towards Industrial Internet platform
- 2019
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Ingår i: IEEE Transactions on Industrial Informatics. - : Institute of Electrical and Electronics Engineers (IEEE). - 1551-3203 .- 1941-0050. ; 15:6, s. 3712-3722
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Tidskriftsartikel (refereegranskat)abstract
- As numerous Industrial Internet platforms emerge, manufacturing services are shared among multiple stakeholders more frequently than ever. The optimal selection of shared manufacturing service composition (MSC) should both promise the task completion and the stakeholders’ satisfaction. However, as commercial entities, stakeholders concentrate on not only the temporary benefits but also the long-term acquisitions. Most of the existing MSC problems neglect the stakeholders’ prospect on the manufacturing service sharing. This leads to the disappointment and dissatisfaction of the stakeholders with long-term expectations, who will abandon the participation in Industrial Internet platform. Therefore, the long/short-term preferences of various stakeholders should be satisfied and balanced. In this paper, the long/short-term preferences of three sides (provider, consumer, and operator) are discussed. And the models considering short-term utility of a consumer and long-term utility of providers, are established. The potential tasks assigned to providers are taken into account to estimate the long-term utility if the current task is accepted. Then, to solve the bi-objective optimization problem, an improved Non-dominated Sorting Genetic Algorithm-II algorithm, combining Tabu search and improved K-means mechanism, is proposed to find the optimal solution set. Finally, the effectiveness of the method is verified by the experimental results in terms of solution diversity, astringency and stability, in which a finding is further observed that the changes of consumers’ preferences have little impact on the long-term utility of providers.
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| 8. |
- Zhao, Peng, et al.
(författare)
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Lentiviral vector mediated siRNA knock-down of hTERT results in diminished capacity in invasiveness and in vivo growth of human glioma cells in a telomere length-independent manner
- 2007
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Ingår i: International Journal of Oncology. - 1019-6439. ; 31:2, s. 361-368
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Tidskriftsartikel (refereegranskat)abstract
- Glioma cells are characterized by their invasiveness and resistance against conventional therapeutics. Telomerase activity has been suggested to be an important target for glioma treatment. Here we assessed the anticancer effects and its potential mechanisms of lentiviral vector mediated siRNA knock-down of the human telomerase reverse transcriptase (hTERT) in U87MG human glioblastoma cells. Stable expression of anti-hTERT siRNA reduced the hTERT expression and TRAP assay telomerase activity to barely detectable levels. Injection of lentiviral vectors encoding anti-hTERT siRNA significantly inhibited the growth of preestablished macroscopic xenograft tumors, which was in contrast to the finding that no obvious effects on cell growth, cell cycle progression and telomere length were observed in anti-hTERT siRNA expressing U87MG cells during short-term in vitro cultures. The in vivo glioma growth inhibition effect was already evident in the period coincided with no detectable telomere length changes, suggesting that hTERT inhibition may hinder glioma cell growth in a telomere length-independent manner. Importantly, transwell migration assay showed profound inhibitory effect on the invasive capacity of U87MG cells following short-term anti-hTERT siRNA expression. Thus, efficient knock-down of hTERT can inhibit glioma cell proliferation and migration prior to its effect on telomere length.
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