| 1. |
- Földváry Ličina, Veronika, et al.
(författare)
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Development of the ASHRAE Global Thermal Comfort Database II
- 2018
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Ingår i: Building and Environment. - : Elsevier BV. - 0360-1323. ; 142, s. 502-512
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Tidskriftsartikel (refereegranskat)abstract
- Recognizing the value of open-source research databases in advancing the art and science of HVAC, in 2014 the ASHRAE Global Thermal Comfort Database II project was launched under the leadership of University of California at Berkeley's Center for the Built Environment and The University of Sydney's Indoor Environmental Quality (IEQ) Laboratory. The exercise began with a systematic collection and harmonization of raw data from the last two decades of thermal comfort field studies around the world. The ASHRAE Global Thermal Comfort Database II (Comfort Database), now an online, open-source database, includes approximately 81,846 complete sets of objective indoor climatic observations with accompanying “right-here-right-now” subjective evaluations by the building occupants who were exposed to them. The database is intended to support diverse inquiries about thermal comfort in field settings. A simple web-based interface to the database enables filtering on multiple criteria, including building typology, occupancy type, subjects' demographic variables, subjective thermal comfort states, indoor thermal environmental criteria, calculated comfort indices, environmental control criteria and outdoor meteorological information. Furthermore, a web-based interactive thermal comfort visualization tool has been developed that allows end-users to quickly and interactively explore the data.
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| 2. |
- Havenith, George, et al.
(författare)
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A Database of Static Clothing Thermal Insulation and Vapor Permeability Values of Non-Western Ensembles for Use in ASHRAE Standard 55, ISO 7730 and ISO 9920
- 2015
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Ingår i: ASHRAE Transactions. - 2378-2129. ; 121:Part 1, s. 197-215
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Tidskriftsartikel (refereegranskat)abstract
- Four different thermal manikins (male and female shapes)in three different laboratories (UK, Sweden, and China) were used to determine the clothing thermal insulation values of 52 non-Western, mainly indoor clothing ensembles in order to expand the existing clothing database for use with ANSI/ASHRAE Standard 55-2013, Thermal Environmental Conditions for Human Occupancy (ASHRAE 2013a), ISO Standard 7730-2005, Ergonomics of the Thermal Environment -- Analytical Determination and Interpretation of Thermal Comfort Using Calculation of the PMV and PPD Indices and LocalThermal Comfort Criteria (ISO 2005), and ISO Standard 9920-2009, Ergonomics of the Thermal Environment -- Estimation of Thermal Insulation and Water Vapour Resistance of a Clothing Ensemble (ISO 2009). Insulation values varied over manikins, which is attributed to their different shapes and the different fit of the clothing. The mean value over three manikins is reported (with standard deviation) to include this potential real-life variation in the results. The relation of the clothing surface area factor to intrinsic clothing insulation was found to be different from that published for Western clothing. Prediction equations for the clothing surface area factor fcl based on the new data had only limited predictive power, which,however, was also the case for those obtained in the past for Western clothing. This issue seems to be commonly overlooked, as the use of these prediction equations is widespread. It has to be concluded that reliable fcl values can only be obtained when they are actually measured, as in the present work. However, we suggest that the concept of the fcl factor for the non-Western clothing may not be appropriate and may require further attention in research, as wide-falling-robes and gowns do not match the cylindrical clothing and air layer model on which the fcl concept is based. In summary, the results provide an extensive database of insulation values of non-Western clothing that is expected to be a valuable addition to ASHRAE Standard 55-2013 (ASHRAE 2013a), ISO Standard 7730-2005 (ISO 2005), and ISO Standard 9920-2009 (ISO 2009).
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| 3. |
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| 4. |
- Thompson, Deborah J, et al.
(författare)
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Genetic predisposition to mosaic Y chromosome loss in blood
- 2019
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 575, s. 652-657
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Tidskriftsartikel (refereegranskat)abstract
- Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common form of clonal mosaicism1-5, yet our knowledge of the causes and consequences of this is limited. Here, using a computational approach, we estimate that 20% of the male population represented in the UK Biobank study (n = 205,011) has detectable LOY. We identify 156 autosomal genetic determinants of LOY, which we replicate in 757,114 men of European and Japanese ancestry. These loci highlight genes that are involved in cell-cycle regulation and cancer susceptibility, as well as somatic drivers of tumour growth and targets of cancer therapy. We demonstrate that genetic susceptibility to LOY is associated with non-haematological effects on health in both men and women, which supports the hypothesis that clonal haematopoiesis is a biomarker of genomic instability in other tissues. Single-cell RNA sequencing identifies dysregulated expression of autosomal genes in leukocytes with LOY and provides insights into why clonal expansion of these cells may occur. Collectively, these data highlight the value of studying clonal mosaicism to uncover fundamental mechanisms that underlie cancer and other ageing-related diseases.
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| 5. |
- W. Smallcombe, James, et al.
(författare)
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Update of clothing database for existing and new Western clothing ensembles, including effects of posture, body and air movement : Report on manikin measurements for ASHRAE 1760-TRP.
- 2021
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- ASHRAE Research Project RP-1760 aimed to update thedatabase of western clothing as used in ANSI/ASHRAE Stan-dard 55-2013, Thermal Environmental Conditions for HumanOccupancy (ASHRAE 2013a), ISO Standard 7730-2005,Ergonomics of the Thermal Environment—Analytical Deter-mination and Interpretation of Thermal Comfort Using Calcu-lation of the PMV and PPD Indices and Local ThermalComfort Criteria (ISO 2005), and ISO Standard 9920-2009,Ergonomics of the Thermal Environment—Estimation ofThermal Insulation and Water Vapor Resistance of a ClothingEnsemble (ISO 2009). The previous database, established inthe 1970s and 1980s, relied mostly on single-zone manikinsand did not provide detail on air and body movement effects oninsulation. Insulation values of up to 70 clothing ensembles(31 male, 39 female) were measured in a static standingposture at 0.2, 0.4, and 1 m/s–1 (0.66, 1.31, and 3.28 ft/s–1) airspeed, walking in 0.2 and 1.0 m.s–1 air speed, and in a sittingposture in 0.2 m.s–1 air speed. Measurements were conductedin three laboratories on three manikins with up to 34 individ-ually controlled zones. In addition, vapor resistance was deter-mined in 31 ensembles. This new database provides total,intrinsic and air insulation values, vapor resistance, and cloth-ing area factors as well as correction factors to estimate thewind and movement effect on clothing insulation. Further-more, the model to estimate the clothing area factor from insu-lation values of the ensembles was updated reflecting changesin commonly worn clothing styles.
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