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Sökning: WFRF:(Margaritis M)

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  • Thomas, HS, et al. (författare)
  • 2019
  • swepub:Mat__t
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  • Drake, TM, et al. (författare)
  • Surgical site infection after gastrointestinal surgery in children: an international, multicentre, prospective cohort study
  • 2020
  • Ingår i: BMJ global health. - : BMJ. - 2059-7908. ; 5:12
  • Tidskriftsartikel (refereegranskat)abstract
    • Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings.MethodsA multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI).ResultsOf 1159 children across 181 hospitals in 51 countries, 523 (45·1%) children were from high HDI, 397 (34·2%) from middle HDI and 239 (20·6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12·8% (51/397) in middle HDI and 24·7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI.ConclusionThe odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.
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  • Guerster, M., et al. (författare)
  • Permanent crewed Mars base by 2030 - Outcomes of an interdisciplinary, multinational student workshop
  • 2018
  • Ingår i: Proceedings of the International Astronautical Congress, IAC 2018. - : International Astronautical Federation, IAF.
  • Konferensbidrag (refereegranskat)abstract
    • Indisputably, we live at the dawn of a novel space exploration era, with the space sector undergoing significant changes. The International Space Station (ISS) is nearing the end of its lifespan and a competitive space industry is emerging. It is characterised by an ongoing redistribution of responsibilities between government agencies and private enterprise, with all stakeholders setting ambitious goals for future missions. Recently, interest in the next crewed space exploration mission has grown continuously. Driven by these developments, the Space Station Design Workshop (SSDW) 2017 in Stuttgart, Germany, posed the challenge to conduct the preliminary analysis and develop a viable proposal for the establishment of a permanent crewed space station in the vicinity of Mars by the year 2030. Two multinational, interdisciplinary teams of twenty students each were given one week to develop their own solutions and present them to experts from industry and academia. The authors, Team Blue, have outlined a design for a Mars surface station, called HUMANS2MARS. This proposal requires the development of mission-specific modules, while the launchers to be used include the foreseen state-of-the-art at the late 2020s, such as the Space Launch System from NASA and Falcon Heavy from SpaceX. Designing such a mission from scratch in one week posed great challenges, either innate in the technical and programmatic difficulties of the mission, or resulting from the time constraints and group dynamics of the project. The main technical challenges can be grouped into two sets. The first includes those related to mass and payload limitations of the mission and launching costs. The second consists of those related to the human element of the mission. Due to the hostile Martian environment, like the extreme radiation levels during transit and unexplored psychological pressure on the crew, the complexities associated with humans introduce significant uncertainties. Potential solutions to the problems discovered have been proposed and are presented in this paper - within the framework of a multicultural and interdisciplinary workshop. The major risks of the proposed mission are identified and possible mitigation strategies and backup scenarios are discussed, thus providing a starting point for future research and detailed studies. The complexity of the mission and nature of the SSDW require addressing a great variety of challenges under severe time constraints. A crucial factor in the success of this effort has been the multidisciplinary and diverse academic background of the participants. This enabled the team to overcome these numerous obstacles in often unconventional ways.
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  • Kalogirou, S., et al. (författare)
  • Bycatch Dynamics from a Small-Scale Shrimp Trap Fishery in the Mediterranean Sea
  • 2022
  • Ingår i: Diversity. - : MDPI AG. - 1424-2818. ; 14:4
  • Tidskriftsartikel (refereegranskat)abstract
    • Small-scale fisheries (SSFs) in the Mediterranean and Black seas play a significant social and economic role, representing 84% of the fishing fleet (70,000 vessels), 26% of total revenue (USD 633 million) and 60% of total employment (150,000 people), with the Food and Agriculture Organization (FAO) recently taking important initiatives to sustain livelihoods. Effective management of important natural fisheries resources that sustain livelihoods requires a holistic approach account-ing for all parts of the catch. Quantitative data on seasonal catch dynamics together with classification of bycatch species to IUCN vulnerability status and associated revenues from retained incidental catch were used to reveal the effect of a small-scale shrimp trap fishery on bycatch. We use three main quantitative variables (i.e., density, biomass and number of bycatch species) and show a positive correlation between bycatch and the seasonal catch dynamics of the target species during late spring and summer. On the contrary, discards were proportionally lower during winter, with the majority of discarded fish species not considered endangered. Six retained species in spring– summer and five discarded species in winter were found to modulate the structure of species’ as-semblage. Out of 55 bycatch species, 26 were retained and 29 discarded. Only four species were considered threatened, all of which were caught in very low numbers (<2 individuals), while the majority of the retained species was not considered endangered. The rapid sorting time (<1 min/per trap) pointed towards a decreased effect on certain discarded crustacean species and a significant reduction in total bycatch with timely haul time (from 71 to 47%). The results of this study can be used when considering future mitigation measures for this fishery, while the methodology used can provide insights into the management of similar trap fisheries worldwide when taking into account the sustainability of SSFs and the regional vulnerability status of bycatch species.
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