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Numrering	Referens	Omslagsbild	Hitta
1.	Santangelo, James S., et al. (författare) Global urban environmental change drives adaptation in white clover 2022 Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 375 Tidskriftsartikel (refereegranskat)abstract Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural dines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale.
2.	Price, Nicholas, et al. (författare) Combining population genomics and fitness QTLs to identify the genetics of local adaptation in Arabidopsis thaliana 2018 Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : NATL ACAD SCIENCES. - 0027-8424 .- 1091-6490. ; 115:19, s. 5028-5033 Tidskriftsartikel (refereegranskat)abstract Evidence for adaptation to different climates in the model species Arabidopsis thaliana is seen in reciprocal transplant experiments, but the genetic basis of this adaptation remains poorly understood. Field-based quantitative trait locus (QTL) studies provide direct but low-resolution evidence for the genetic basis of local adaptation. Using high-resolution population genomic approaches, we examine local adaptation along previously identified genetic trade-off (GT) and conditionally neutral (CN) QTLs for fitness between locally adapted Italian and Swedish A. thaliana populations [angstrom gren J, et al. (2013) Proc Natl Acad Sci USA 110: 21077-21082]. We find that genomic regions enriched in high F-ST SNPs colocalize with GT QTL peaks. Many of these high F-ST regions also colocalize with regions enriched for SNPs significantly correlated to climate in Eurasia and evidence of recent selective sweeps in Sweden. Examining unfolded site frequency spectra across genes containing high F-ST SNPs suggests GTs may be due to more recent adaptation in Sweden than Italy. Finally, we collapse a list of thousands of genes spanning GT QTLs to 42 genes that likely underlie the observed GTs and explore potential biological processes driving these trade-offs, from protein phosphorylation, to seed dormancy and longevity. Our analyses link population genomic analyses and field-based QTL studies of local adaptation, and emphasize that GTs play an important role in the process of local adaptation.

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Typ av publikation: tidskriftsartikel (2)

Typ av innehåll: refereegranskat (2)

Författare/redaktör: Tack, Ayco J. M. (1); Ågren, Jon (1); Alberti, Marina (1); Pinho, Pedro (1); Puentes, Adriana (1); Laine, Anna Liisa (1); visa fler...; Bonte, Dries (1); del Val, Ek (1); Branquinho, Cristina (1); Peres-Neto, Pedro R. (1); Lasky, Jesse R (1); Granath, Gustaf (1); Crawford, Andrew J. (1); Kern, Andrew D. (1); Classen, Aimée T. (1); Sanders, Nathan J. (1); Ellers, Jacintha (1); Raeymaekers, Joost A ... (1); Brans, Kristien, I (1); Gagnon, Edeline (1); Scheepens, J.F. (1); Parachnowitsch, Amy ... (1); Santangelo, James S. (1); Ness, Rob W. (1); Angeoletto, Fabio (1); Anstett, Daniel N. (1); Anstett, Julia (1); Baena-Diaz, Fernanda (1); Carlen, Elizabeth J. (1); Chaves, Jaime A. (1); Comerford, Mattheau ... (1); Dyson, Karen (1); Falahati-Anbaran, Mo ... (1); Fellowes, Mark D. E. (1); Hodgins, Kathryn A. (1); Iñiguez-Armijos, Car ... (1); Lázaro-Lobo, Adrián (1); Moles, Angela T. (1); Munshi-South, Jason (1); Paule, Juraj (1); Porth, Ilga M. (1); Santiago-Rosario, Lu ... (1); Whitney, Kaitlin Sta ... (1); Johnson, Marc T. J. (1); Rivas-Torres, Gonzal ... (1); Anderson, Jill T. (1); Dominoni, Davide M. (1); Szulkin, Marta (1); DiLeo, Michelle F. (1); Oakley, Christopher ... (1); visa färre...

Lärosäte: Uppsala universitet (2); Stockholms universitet (1); Lunds universitet (1); Karlstads universitet (1); Sveriges Lantbruksuniversitet (1)

Språk: Engelska (2)

Forskningsämne (UKÄ/SCB): Naturvetenskap (2)

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