| 1. |
- Rutgersson, Anna, 1971-, et al.
(författare)
-
Using land-based stations for air–sea interaction studies
- 2020
-
Ingår i: Tellus. Series A, Dynamic meteorology and oceanography. - : Informa UK Limited. - 0280-6495 .- 1600-0870. ; 72:1, s. 1-23
-
Tidskriftsartikel (refereegranskat)abstract
- In situ measurements representing the marine atmosphere and air-sea interaction are taken at ships, buoys, stationary moorings and land-based towers, where each observation platform has structural restrictions. Air-sea fluxes are often small, and due to the limitations of the sensors, several corrections are applied. Land-based towers are convenient for long-term observations, but one critical aspect is the representativeness of marine conditions. Hence, a careful analysis of the sites and the data is necessary. Based on the concept of flux footprint, we suggest defining flux data from land-based marine micrometeorological sites in categories depending on the type of land influence:1. CAT1: Marine data representing open sea,2. CAT2: Disturbed wave field resulting in physical properties different from open sea conditions and heterogeneity of water properties in the footprint region, and3. CAT3: Mixed land-sea footprint, very heterogeneous conditions and possible active carbon production/consumption.Characterization of data would be beneficial for combined analyses using several sites in coastal and marginal seas and evaluation/comparison of properties and dynamics. Aerosol fluxes are a useful contribution to characterizing a marine micrometeorological field station; for most conditions, they change sign between land and sea sectors. Measured fluxes from the land-based marine station Ostergarnsholm are used as an example of a land-based marine site to evaluate the categories and to present an example of differences between open sea and coastal conditions. At the Ostergarnsholm site the surface drag is larger for CAT2 and CAT3 than for CAT1 when wind speed is below 10m/s. The heat and humidity fluxes show a distinctive distinguished seasonal cycle; latent heat flux is larger for CAT2 and CAT3 compared to CAT1. The flux of carbon dioxide is large from the coastal and land-sea sectors, showing a large seasonal cycle and significant variability (compared to the open sea sector). Aerosol fluxes are partly dominated by sea spray emissions comparable to those observed at other open sea conditions.
|
|
| 2. |
- Tomic, Tajana Tesan, et al.
(författare)
-
MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression
- 2020
-
Ingår i: PLOS Genetics. - : Public Library of Science. - 1553-7390 .- 1553-7404. ; 16:6
-
Tidskriftsartikel (refereegranskat)abstract
- Identification of additional cancer-associated genes and secondary mutations driving the metastatic progression in pheochromocytoma and paraganglioma (PPGL) is important for subtyping, and may provide optimization of therapeutic regimens. We recently reported novel recurrent nonsynonymous mutations in the MYO5B gene in metastatic PPGL. Here, we explored the functional impact of these MYO5B mutations, and analyzed MYO5B expression in primary PPGL tumor cases in relation to mutation status. Immunohistochemistry and mRNA expression analysis in 30 PPGL tumors revealed an increased MYO5B expression in metastatic compared to non-metastatic cases. In addition, subcellular localization of MYO5B protein was altered from cytoplasmic to membranous in some metastatic tumors, and the strongest and most abnormal expression pattern was observed in a paraganglioma harboring a somatic MYO5B:p.G1611S mutation. In addition to five previously discovered MYO5B mutations, the present study of 30 PPGL (8 previous and 22 new samples) also revealed two, and hence recurrent, mutations in the gene paralog MYO5A. The three MYO5B missense mutations with the highest prediction scores (p.L587P, p.G1611S and p.R1641C) were selected and functionally validated using site directed mutagenesis and stable transfection into human neuroblastoma cells (SK-N-AS) and embryonic kidney cells (HEK293). In vitro analysis showed a significant increased proliferation rate in all three MYO5B mutated clones. The two somatically derived mutations, p.L587P and p.G1611S, were also found to increase the migration rate. Expression analysis of MYO5B mutants compared to wild type clones, demonstrated a significant enrichment of genes involved in migration, proliferation, cell adhesion, glucose metabolism, and cellular homeostasis. Our study validates the functional role of novel MYO5B mutations in proliferation and migration, and suggest the MYO5-pathway to be involved in the malignant progression in some PPGL tumors. © 2020 Tomic et al.
|
|
| 3. |
- Esters, Leonie, et al.
(författare)
-
Non-local Impacts on Eddy-Covariance Air–Lake CO2 Fluxes
- 2021
-
Ingår i: Boundary-layer Meteorology. - : Springer Nature. - 0006-8314 .- 1573-1472. ; 178:2, s. 283-300
-
Tidskriftsartikel (refereegranskat)abstract
- Inland freshwater bodies form the largest natural source of carbon to the atmosphere. To study this contribution to the atmospheric carbon cycle, eddy-covariance flux measurements at lake sites have become increasingly popular. The eddy-covariance method is derived for solely local processes from the surface (lake). Non-local processes, such as entrainment or advection, would add erroneous contributions to the eddy-covariance flux estimations. Here, we use four years of eddy-covariance measurements of carbon dioxide from Lake Erken, a freshwater lake in mid-Sweden. When the lake is covered with ice, unexpected lake fluxes were still observed. A statistical approach using only surface-layer data reveals that non-local processes produce these erroneous fluxes. The occurrence and strength of non-local processes depend on a combination of wind speed and distance between the instrumented tower and upwind shore (fetch), which we here define as the time over water. The greater the wind speed and the shorter the fetch, the higher the contribution of non-local processes to the eddy-covariance fluxes. A correction approach for the measured scalar fluxes due to the non-local processes is proposed and also applied to open-water time periods. The gas transfer velocity determined from the corrected fluxes is close to commonly used wind-speed based parametrizations.
|
|
| 4. |
- Gutiérrez Loza, Lucia, et al.
(författare)
-
Measurement of air-sea methane fluxes in the Baltic Sea using the eddy covariance method
- 2019
-
Ingår i: Frontiers in Earth Science. - : Frontiers Media SA. - 2296-6463. ; 7
-
Tidskriftsartikel (refereegranskat)abstract
- Methane (CH4) is the second-most important greenhouse gas in the atmosphere having a significant effect on global climate. The ocean-particularly the coastal regions-have been recognized to be a net source of CH4, however, the constraints on temporal and spatial resolution of CH4 measurements have been the limiting factor to estimate the total oceanic contributions. In this study, the viability of micrometeorological methods for the analysis of CH4 fluxes in the marine environment was evaluated. We present 1 year of semi-continuous eddy covariance measurements of CH4 atmospheric dry mole fractions and air-sea CH4 flux densities at the Ostergarnsholm station at the east coast of the Gotland Island in the central Baltic Sea. The mean annual CH4 flux density was positive, indicating that the region off Gotland is a net source of CH4 to the atmosphere with monthly mean flux densities ranging between -0.1 and 36 nmol m(-2)s(-1). Both the air-water concentration gradient and the wind speed were found to be crucial parameters controlling the flux. The results were in good agreement with other measurements in the Baltic Sea reported in the MEMENTO database. Our results suggest that the eddy covariance technique is a useful tool for studying CH4 fluxes and improving the understanding of air-sea gas exchange processes with high-temporal resolution. Potentially, the high resolution of micrometeorological data can increase the understanding of the temporal variability and forcing processes of CH4 flux.
|
|
| 5. |
- Gutiérrez Loza, Lucia, et al.
(författare)
-
On physical mechanisms enhancing air-sea CO2 exchange
- 2022
-
Ingår i: Biogeosciences. - : European Geosciences Union (EGU). - 1726-4170 .- 1726-4189. ; 19:24, s. 5645-5665
-
Tidskriftsartikel (refereegranskat)abstract
- Reducing uncertainties in the air–sea CO2 flux calculations is one of the major challenges when addressing the oceanic contribution in the global carbon balance. In traditional models, the air–sea CO2 flux is estimated using expressions of the gas transfer velocity as a function of wind speed. However, other mechanisms affecting the variability in the flux at local and regional scales are still poorly understood. The uncertainties associated with the flux estimates become particularly large in heterogeneous environments such as coastal and marginal seas. Here, we investigated the air–sea CO2 exchange at a coastal site in the central Baltic Sea using nine years of eddy covariance measurements. Based on these observations we were able to capture the temporal variability of the air–sea CO2 flux and other parameters relevant for the gas exchange. Our results show that a wind-based model with similar pattern to those developed for larger basins and open sea condition can, on average, be a good approximation for k. However, in order to reduce the uncertainty associated to these averages and produce reliable short-term k estimates, additional physical processes must be considered. Using a normalized gas transfer velocity, we identified conditions associated to enhanced exchange (large k values). During high and intermediate wind speeds (above 6–8 m s−1),conditions on both sides of the air–water interface were found to be relevant for the gas exchange. Our findings further suggest that at such relatively high wind speeds, sea spray is an efficient mechanisms for air–sea CO2 exchange. During low wind speeds (<6 m s−1), water-side convection was found to be a relevant control mechanism. The effect of both sea spray and water-side convection on the gas exchange showed a clear seasonality with positive fluxes (winter conditions) being the most affected.
|
|
| 6. |
- Hallgren, Christoffer, et al.
(författare)
-
Classification and properties of non-idealized coastal wind profiles - an observational study
- 2022
-
Ingår i: Wind Energy Science. - : Copernicus Publications. - 2366-7443 .- 2366-7451. ; 7:3, s. 1183-1207
-
Tidskriftsartikel (refereegranskat)abstract
- Non-idealized wind profiles frequently occur over the Baltic Sea and are important to take into consideration for offshore wind power, as they affect not only the power production but also the loads on the structure and the behavior of the wake behind the turbine. In this observational study, we classified non-idealized profiles as the following wind profiles having negative shear in at least one part of the lidar wind profile between 28 and 300 m: low-level jets (with a local wind maximum in the profile), profiles with a local minimum and negative profiles. Using observations spanning over 3 years, we show that these non-idealized profiles are common over the Baltic Sea in late spring and summer, with a peak of 40 % relative occurrence in May. Negative profiles (in the 28-300 m layer) mostly occurred during unstable conditions, in contrast to low-level jets that primarily occurred in stable stratification. There were indications that the strong shear zone of low-level jets could cause a relative suppression of the variance for large turbulent eddies compared to the peak of the velocity spectra, in the layer below the jet core. Swell conditions were found to be favorable for the occurrence of negative profiles and profiles with a local minimum, as the waves fed energy into the surface layer, resulting in an increase in the wind speed from below.
|
|
| 7. |
|
|
| 8. |
- Högström, Ulf, et al.
(författare)
-
Surface Stress over the Ocean in Swell-Dominated Conditions during Moderate Winds
- 2015
-
Ingår i: Journal of the Atmospheric Sciences. - 0022-4928 .- 1520-0469. ; 72:12, s. 4777-4795
-
Tidskriftsartikel (refereegranskat)abstract
- Atmospheric and surface wave data from several oceanic experiments carried out on the Floating Instrument Platform(FLIP) and the Air–Sea Interaction Spar (ASIS) have been analyzed with the purpose of identifying swell-related effects on the surface momentum exchange during near-neutral atmospheric conditions and wind-following or crosswind seas. All data have a pronounced negative maximum in uw cospectra centered at the frequency of the dominant swell np, meaning a positive contribution to the stress. A similar contribution at this frequency is also obtained for the corresponding crosswind cospectrum. The magnitude of the cospectral maximum is shown to be linearly related to the square of the orbital motion, being equal to , where Hsd is the swell-significant wave height, the effect tentatively being due to strong correlation between the surface component of the orbital motion and the pattern of capillary waves over long swell waves.A model for prediction of the friction velocity from measurements of Hsd, np, and the 10-m wind speed U10 is formulated and tested against an independent dataset of ~400 half-hour measurements during swell, giving good result.The model predicts that the drag coefficient CD, which is traditionally modeled as a function of U10 alone (e.g., the COARE algorithm), becomes strongly dependent on the magnitude of the swell factor and that CD can attain values several times larger than predicted by wind speed–only models. According to maps of the global wave climate, conditions leading to large effects are likely to be widespread over the World Ocean.
|
|
| 9. |
- Högström, Ulf, et al.
(författare)
-
The Transition from Downward to Upward Air–Sea Momentum Flux in Swell-Dominated Light Wind Conditions
- 2018
-
Ingår i: Journal of the Atmospheric Sciences. - 0022-4928 .- 1520-0469. ; 75:8, s. 2579-2588
-
Tidskriftsartikel (refereegranskat)abstract
- Fifteen hours of consecutive swell data from the experiment Flux, État de la Mer, et Télédétection en Condition de Fetch Variable (FETCH) in the Mediterranean show a distinct upward momentum flux. The characteristics are shown to vary systematically with wind speed. A hysteresis effect is found for wave energy of the wind-sea waves when represented as a function of wind speed, displaying higher energy during decaying winds compared to increasing winds. For the FETCH measurements, the upward momentum transfer regime is found to begin for wind speeds lower than about U 5 4ms21 . For the lowest observed wind speeds U , 2.4 m s21 , the water surface appears to be close to dynamically smooth. In this range almost all the upward momentum flux is accomplished by the peak in the cospectrum between the vertical and horizontal components of the wind velocity. It is demonstrated that this contribution in turn is linearly related to the swell significant wave height Hsd in the range 0.6 , Hsd , 1.4 m. For Hsd , 0.6 m, the contribution is zero in the present dataset but may depend on the swell magnitude in other situations. It is speculated that the observed upward momentum flux in the smooth regime, which is so strongly related to the cospectral peak at the dominant swell frequency, might be caused by the recirculation mechanism found by Wen and Mobbs in their numerical simulation of laminar flow of a nonlinear progressive wave at low wind speed
|
|
| 10. |
|
|
