| 1. |
- Alijagic, Andi, 1992-, et al.
(författare)
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A Novel Nanosafety Approach Using Cell Painting, Metabolomics, and Lipidomics Captures the Cellular and Molecular Phenotypes Induced by the Unintentionally Formed Metal-Based (Nano)Particles
- 2023
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Ingår i: Cells. - : MDPI. - 2073-4409. ; 12:2
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Tidskriftsartikel (refereegranskat)abstract
- Additive manufacturing (AM) or industrial 3D printing uses cutting-edge technologies and materials to produce a variety of complex products. However, the effects of the unintentionally emitted AM (nano)particles (AMPs) on human cells following inhalation, require further investigations. The physicochemical characterization of the AMPs, extracted from the filter of a Laser Powder Bed Fusion (L-PBF) 3D printer of iron-based materials, disclosed their complexity, in terms of size, shape, and chemistry. Cell Painting, a high-content screening (HCS) assay, was used to detect the subtle morphological changes elicited by the AMPs at the single cell resolution. The profiling of the cell morphological phenotypes, disclosed prominent concentration-dependent effects on the cytoskeleton, mitochondria, and the membranous structures of the cell. Furthermore, lipidomics confirmed that the AMPs induced the extensive membrane remodeling in the lung epithelial and macrophage co-culture cell model. To further elucidate the biological mechanisms of action, the targeted metabolomics unveiled several inflammation-related metabolites regulating the cell response to the AMP exposure. Overall, the AMP exposure led to the internalization, oxidative stress, cytoskeleton disruption, mitochondrial activation, membrane remodeling, and metabolic reprogramming of the lung epithelial cells and macrophages. We propose the approach of integrating Cell Painting with metabolomics and lipidomics, as an advanced nanosafety methodology, increasing the ability to capture the cellular and molecular phenotypes and the relevant biological mechanisms to the (nano)particle exposure.
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| 2. |
- Alinejadian, Navid, et al.
(författare)
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Electro-deposited nano-Ni/reduced graphene oxide composite film of corrugated surface for high voltammetric sensitivity
- 2023
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Ingår i: Materials Chemistry and Physics. - : Elsevier BV. - 0254-0584 .- 1879-3312. ; 297, s. 127288-
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Tidskriftsartikel (refereegranskat)abstract
- Reduced graphene oxide (rGO) is an ideal candidate in nanostructured metallic materials to enhance their electrochemical performance. However, few studies exist on the effects of rGO on the crystallographic, physical, and topological properties of co-electrodeposited Ni/rGO nanocomposites. In this study, the morphology and normalized electro-active specific surface (NESS) of a Ni/rGO nanocomposite were correlated with its crystal-lographic properties by varying the applied co-electrodeposition current density (0.01-0.1 A cm(-2)) and rGO concentration (0.5-2 mg mL(-1)). Tuning was done to achieve the best physical and electrochemical properties of the nanocomposite at alkaline (NaOH) conditions in terms of the highest NESS (12.3 x 10(-4)) and electro-active sensitivity (17.3 mu A mM(-1) cm(-2)) possible. The findings of the study show a possible approach to enhance the performance of electro-active components such as electrochemical devices, sensors, and actuators.
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| 3. |
- Alinejadian, Navid, et al.
(författare)
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Importance of the micro-lattice structure of selective laser melting processed Mo/Mo(x)S(x+1) composite : Corrosion studies on the electrochemical performance in aqueous solutions
- 2022
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Ingår i: Materials Today Chemistry. - : Elsevier BV. - 2468-5194. ; 26
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Tidskriftsartikel (refereegranskat)abstract
- Selective laser melting (SLM) based processing of Mo-based samples is challenging due to solidification cracking. We here demonstrate that the addition of 2 wt% MoS2 to the Mo feedstock markedly improves crack mitigation of SLM-processed Mo/MoS2/Mo2S3 composite micro-lattice structures (SLM-Mo/ Mo(x)S(x+1)). Crack inhibition is suggested to be a result of Mo2S3 formation, decreased lattice strain (0.04 4%), and a decrease in accumulated residual stresses. The increased values of polarization resistance from 42.3 and 19.2 kU cm2 to 437 and 78.2 kU cm2, respectively verified the hindering effect of the composition on stress corrosion cracking (SCC) and surface oxidation cracking. However, an increased corrosion current density, from 1.22 to 10.2 mA/cm2, and cathodic Tafel constant, from 175 to 260.5 mV, confirmed the decreased polarization resistance and occurrence of different types of corrosion such as SCC and pitting. The strategy to add 2 wt% MoS2 to the Mo feedstock enables the fabrication of hightemperature micro-lattice structure components with improved corrosion resistance properties applicable in e.g., electronic, power semiconductor heat sinks, offshore-, aerospace-, defense-, or particularly novel sodium-ion energy storage applications.
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| 4. |
- Alinejadian, Navid, et al.
(författare)
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Progress in additive manufacturing of MoS2-based structures for energy storage applications - A review
- 2022
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Ingår i: Materials Science in Semiconductor Processing. - : Elsevier BV. - 1369-8001 .- 1873-4081. ; 139
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Forskningsöversikt (refereegranskat)abstract
- Investigation of next-generation manufacturing methods for the processing of functional materials and offering products with improved performance/functionalities has always been a challenge in terms of energy efficiency, cost-effectiveness, and eco-friendliness. Additive manufacturing (AM) attributes to rapid prototyping techniques that provide new opportunities to test new concepts and design complex 3D structures from metals, ceramics, and composites. Moreover, as a well-known transition metal dichalcogenide, Molybdenum disulfide (MoS2) is a two-dimensional (2D) material with outstanding electrochemical, physical, and mechanical properties that make it a potential candidate for energy storage electrodes via intercalation of different H+, Li+, Na+, and K+ cations. In this review, we discuss the existing conventional MoS2-processing methodologies and compare them with the novel additive manufacturing processes (especially laser-based powder bed fusion). The authors are convinced that the processing of prominent MoS2-based functional structures by the novel additive manufacturing processes can provide complex structures for different electrochemical applications, particularly for energy conversion/ storage systems.
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| 5. |
- Alinejadian, Navid, et al.
(författare)
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SLM-processed MoS2/Mo2S3 nanocomposite for energy conversion/storage applications
- 2022
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Ingår i: Scientific Reports. - : Nature Research. - 2045-2322. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- MoS2-based nanocomposites have been widely processed by a variety of conventional and 3D printing techniques. In this study, selective laser melting (SLM) has for the first time successfully been employed to tune the crystallographic structure of bulk MoS2 to a 2H/1T phase and to distribute Mo2S3 nanoparticles in-situ in MoS2/Mo2S3 nanocomposites used in electrochemical energy conversion/storage systems (EECSS). The remarkable results promote further research on and elucidate the applicability of laser-based powder bed processing of 2D nanomaterials for a wide range of functional structures within, e.g., EECSS, aerospace, and possibly high-temperature solid-state EECSS even in space.
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| 6. |
- Atapour, Masoud, et al.
(författare)
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Corrosion and metal release investigations of selective laser melted 316L stainless steel in a synthetic physiological fluid containing proteins and in diluted hydrochloric acid
- 2020
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Ingår i: Electrochimica Acta. - : Elsevier BV. - 0013-4686 .- 1873-3859. ; 354
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Tidskriftsartikel (refereegranskat)abstract
- The corrosion and metal release characteristics of additively manufactured stainless steels are key factors for their applicability in biomedical applications. The effect of building direction on the microstructure, corrosion behavior and metal release of selective laser melted (SLM) AISI 316L stainless steel were therefore investigated in a protein-rich synthetic body fluid (PBS+BSA, pH 7.3) and in diluted hydrochloric acid (HCl, pH 1.5). A multi-analytical approach was applied to characterize SLM 316L surfaces printed in different building directions (denoted XY and XZ) and a post heat treated SLM surface (XZ-HT) compared with wrought surfaces. All SLM specimens revealed an austenitic microstructure without any amounts of delta-ferrite and without large-angled grain boundaries in contrast to the wrought 316L surface. The building direction strongly affected the grain size distribution due to the temperature gradients in the melt pools. The SLM 316L specimens released initially slightly less Fe, Cr and Ni compared with the wrought 316L specimen. Slightly less metal was released from the heat treated SLM specimen (XZ-HT) specimen compared to the other SLM specimens. Relatively high amounts of released Cr were observed in PBS+BSA, most probably attributed to protein-bound Cr, whereas substantially more Ni was released in HCl compared to PBS+BSA due to pitting corrosion and a reduced surface oxide thickness. The surface oxide composition of as-printed SLM specimens was strongly dependent on the building direction and the post heat treatment, whereas no differences were observed after abrasion either among the SLM specimens or compared with the wrought 316L specimen. Cr became in all cases enriched within the outermost surface oxide in PBS+BSA and strongly enriched in the HCl solution, coupled to a strongly reduced amount of released metals with time. The heat treated SLM specimen (XZ-HT) gained a superior charge transfer resistance, the lowest passive current density, and the highest OCP value among all specimens. In HCl, the SLM specimens showed a lower pitting susceptibility compared to the wrought specimens. No pitting was observed in PBS+BSA. No differences in corrosion or metal release characteristics were observed related to the building direction of abraded SLM specimens.
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| 7. |
- Atapour, Masoud, et al.
(författare)
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Corrosion of Binder Jetting Additively Manufactured 316L Stainless Steel of Different Surface Finish
- 2020
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Ingår i: Journal of the Electrochemical Society. - : The Electrochemical Society. - 0013-4651 .- 1945-7111. ; 167:13
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Tidskriftsartikel (refereegranskat)abstract
- One technique of additive manufacturing is the binder-jetting technique that has the advantages of low costs, printing at room temperature and in air, and no need of a support structure. The aim of this study was to investigate the corrosion behavior of printed 316L surfaces with and without different post surface treatments of blasting and superfinishing. Comparative studies were performed on abraded wrought 316L. Surface topography, porosity, surface oxide composition, and electrochemical characteristics, including pitting corrosion, were investigated at room temperature as a function of post surface treatments in diluted hydrochloric acid at pH 1.5. The blasting and superfinishing treatment significantly reduced the surface roughness and level of surface porosity. Blasting detrimentally affected on the pitting corrosion resistance. The superfinishing process induced an enrichment of chromium in the surface oxide and improved the pitting corrosion resistance. All surfaces revealed slightly reduced susceptibility to pit initiation and metastable pitting as compared to wrought 316L, possibly explained by the absence of inclusions. Once pitting propagation was induced, repassivation was hindered for all surfaces compared with the wrought surface. The pitting corrosion resistance of the as-superfinished 316L was improved compared with wrought 316L.
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| 8. |
- Atapour, Masoud, et al.
(författare)
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Metal release from stainless steel 316L in whey protein - And simulated milk solutions under static and stirring conditions
- 2019
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Ingår i: Food Control. - : ELSEVIER SCI LTD. - 0956-7135 .- 1873-7129. ; 101, s. 163-172
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Tidskriftsartikel (refereegranskat)abstract
- Stainless steel is an important transport and processing contact material for bovine milk and dairy products. Release (migration) of metals, ions, complexes or wear debris/particles, and metal-induced protein aggregation in such environments are hence important to consider both from a corrosion and food safety perspective. This study aims on investigating the release of iron (Fe), chromium (Cr), and nickel (Ni) from AISI 316L stainless steel in contact with whey protein solutions relevant for protein drinks, and on how the whey proteins are influenced by stirring with a magnetic stir bar and metal release. Mechanistic insight is gained by parallel investigations of metal release from two reference non-protein containing solutions, a metal-complexing (citrate-containing) simulated milk solution (SMS) and a low complexing phosphate buffered saline solution (PBS). All immersion exposures were conducted at pH 6.8 for 0.5, 4, 24 and 48 hat room temperature at static and stirring conditions. All solutions and samples were investigated using different chemical, spectroscopic, microscopic, and electrochemical methods. Significantly higher amounts of Fe, Cr, and Ni were released into the whey protein solution (80 g/L) as compared to SMS and PBS. Strong enrichment of Cr in the surface oxide and reduction of the surface oxide thickness were associated with a higher amount of Ni release in the metal-complexing solutions (SMS and whey protein) compared with PBS. Stirring conditions resulted in higher amounts of metal release, enrichment of Cr in the surface oxide, and clear signs of wear of the 316L surface in all solutions compared to static conditions. The wear mechanism in the whey protein solution was different as compared to corresponding processes in SMS and PBS, involving an etching-like process and larger-sized wear debris. Electrochemical measurements at static conditions confirmed observed differences between the solutions, with the lowest corrosion resistance observed for coupons exposed in the whey protein solution, followed by SMS and PBS. Released metals in solution from the 316L coupons in contact with the whey protein solution resulted in enhanced rates of protein aggregation and precipitation of protein aggregates from solution. Further studies should be made to investigate other relevant test conditions and assess toxicological risks.
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| 9. |
- Atapour, Masoud, et al.
(författare)
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Stainless steel in simulated milk and whey protein solutions - Influence of grade on corrosion and metal release
- 2020
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Ingår i: Electrochimica Acta. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0013-4686 .- 1873-3859. ; 331
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Tidskriftsartikel (refereegranskat)abstract
- Reactions at the biointerfaces between stainless steel and protein-rich dairy products, which contain whey proteins, are important to consider in terms of food safety and material grade selection. Changes in corrosion behavior, metal release, and surface composition of austenitic (AISI 316 L), ferritic (AISI 430), and lean duplex (LDX 2101) stainless steels in simulated milk (SMS) and whey protein solution were investigated. The amount of released metals and the corrosion susceptibility increased according to 2101 < 316 L < 430. All grades revealed low corrosion rates in the whey protein solution without any sign of active/metastable corrosion. Pitting corrosion was evident for 430 in SMS. The total amount of released metals (iron, chromium, and nickel) was significantly higher in whey protein solution compared with SMS. This suggests the metal release process to be mainly governed by complexation reactions. Nickel was preferentially released compared to its bulk composition fraction for both 316 L and 2101 in the highly complexing SMS. Reduced metal release rates with time correlated with the enrichment of chromium in the surface oxide. The extent of metal release was for all metals substantially lower than release limits of metals stipulated in health regulations related to the use of alloys and metals in food-related environments.
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| 10. |
- Bahar, Babak, et al.
(författare)
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Corrosion-induced copper release from rain gutters
- 2008
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Ingår i: Metall (Berlin. 1947). - 0026-0746. ; 62:3, s. 129-135
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Tidskriftsartikel (refereegranskat)abstract
- While runoff rates from copper roofs have been extensively studied during the last years, corresponding studies from copper rain gutters have been missing. A laboratory investigation has been undertaken to examine the influence of important runoff water parameters on the copper runoff from rain gutters. At a given rainfall quantity, the release rate of copper increases with decreasing runoff water intensity and decreasing degree of gutter inclination, and with increasing runoff acidity and increasing Cu2+-ion concentration in the runoff water. A comparison of the predicted long-term copper release from the gutter-system compared to the roof on a real building suggests that less than 5% of the total copper runoff originates from the gutter. However, single rain events may result in higher release rates, especially during the initial rain portion.
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