| 1. |
- Andersson, Martin
(författare)
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Churning losses and efficiency in gearboxes
- 2014
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Efficient transmissions systems are key to producing competitive motor vehicles that have a smaller environmental impact. Gears are the main components in vehicle transmissions and although they are already highly efficient, there is still room for improvement. In this study, the focus falls on the lubricant used to create separating films between gears and todissipate heat. When driving, the gears churn this lubricant, giving rise to power losses that are related to the amount and properties of the lubricant. However, any attempt to reduce these losses must not compromise the required lubrication and heat dissipation. Paper A reports on the use of an FZG gear test rig to investigate power losses and heat generation for different gear immersion depths, surface roughness and coatings. The results show that lower gear roughness reduces gear mesh losses and heat generation. A polishing affect was obtained when a non-coated gear ran against a coated gear.The aim of the research reported in paper B was to increase the accuracy of efficiency testing. It investigated how and whether repeated disassembly and re-assembly of the same test equipment, as well as test performance and rig conditions, affect the measured torque loss in an FZG gear test rig. It was shown that the measured torque loss changes between one assembly and another. Repeatability between tests is crucial for accurate conclusions.The aim of the research reported in paper C was to study whether gear efficiency could be increased by a running-in procedure, which would reduce the need for a coolant. A back-to-back gear test rig was used to test two running-in loads. Higher gear mesh efficiency was seen when a higher running-in load was used.
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| 2. |
- Levin, Malin, 1973, et al.
(författare)
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Evaluation of macrophage-specific promoters using lentiviral delivery in mice.
- 2012
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Ingår i: Gene therapy. - : Springer Science and Business Media LLC. - 1476-5462 .- 0969-7128. ; 19:11, s. 1041-7
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Tidskriftsartikel (refereegranskat)abstract
- In gene therapy, tissue-specific promoters are useful tools to direct transgene expression and improve efficiency and safety. Macrophage-specific promoters (MSPs) have previously been published using different delivery systems. In this study, we evaluated five different MSPs fused with green fluorescent protein (GFP) to delineate the one with highest specificity using lentiviral delivery. We compared three variants of the CD68 promoter (full length, the 343-bp proximal part and the 150-bp proximal part) and two variants (in forward and reverse orientation) of a previously characterized synthetic promoter derived from elements of transcription factor genes. We transduced a number of cell lines and primary cells in vitro. In addition, hematopoietic stem cells were transduced with MSPs and transferred into lethally irradiated recipient mice. Fluorescence activated cell sorting analysis was performed to determine the GFP expression in different cell populations both in vitro and in vivo. We showed that MSPs can efficiently be used for lentiviral gene delivery and that the 150-bp proximal part of the CD68 promoter provides primarily macrophage-specific expression of GFP. We propose that this is the best currently available MSP to use for directing transgene expression to macrophage populations in vivo using lentiviral vectors.
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| 3. |
- Perman, Jeanna, 1981, et al.
(författare)
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The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction.
- 2011
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Ingår i: The Journal of clinical investigation. - : American Society for Clinical Investigation. - 1558-8238 .- 0021-9738. ; 121:7, s. 2625-40
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Tidskriftsartikel (refereegranskat)abstract
- Impaired cardiac function is associated with myocardial triglyceride accumulation, but it is not clear how the lipids accumulate or whether this accumulation is detrimental. Here we show that hypoxia/ischemia-induced accumulation of lipids in HL-1 cardiomyocytes and mouse hearts is dependent on expression of the VLDL receptor (VLDLR). Hypoxia-induced VLDLR expression in HL-1 cells was dependent on HIF-1α through its interaction with a hypoxia-responsive element in the Vldlr promoter, and VLDLR promoted the endocytosis of lipoproteins. Furthermore, VLDLR expression was higher in ischemic compared with nonischemic left ventricles from human hearts and was correlated with the total lipid droplet area in the cardiomyocytes. Importantly, Vldlr-/- mice showed improved survival and decreased infarct area following an induced myocardial infarction. ER stress, which leads to apoptosis, is known to be involved in ischemic heart disease. We found that ischemia-induced ER stress and apoptosis in mouse hearts were reduced in Vldlr-/- mice and in mice treated with antibodies specific for VLDLR. These findings suggest that VLDLR-induced lipid accumulation in the ischemic heart worsens survival by increasing ER stress and apoptosis.
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| 4. |
- Alemani, Mattia, et al.
(författare)
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Dry sliding of a low steel friction material against cast iron at different loads : Characterization of the friction layer and wear debris
- 2017
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Ingår i: Wear. - : Elsevier. - 0043-1648 .- 1873-2577. ; 376-377, s. 1450-1459
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Tidskriftsartikel (refereegranskat)abstract
- Pin-on-disc testing was used to investigate the sliding behavior and the wear products of a low-steel friction material against a cast iron disc at different applied loads, to investigate the effect of the temperature rise induced by frictional heating. The testing rig was operated in a clean chamber with a purified incoming air flux. The outgoing flux carries the wear particles to an impactor that counted and sorted them by average diameter and weight. At increasing applied loads, corresponding to a proportional increase of the pin-disc contact temperature, the coverage of both the pin and disc surface by a friction layer was found to increase too. The relevant X-Ray diffraction patterns revealed the presence of a large amount of graphite and different compounds originating from the friction material and from the counterface disc, mainly iron oxides, as concerns this latter. After the test at the lowest investigated load, i.e., 1 kg, the disc worn surface exhibited abrasive grooves and a discontinuous friction layer mainly made of compacted iron oxide particles. After the test at higher loads, i.e., 5 and 7 kg, the disc surface was covered by a compact friction layer. As concerns the friction layer on the pins, most of the ingredients from the friction material were detected, in association with the iron oxides from the disc. These results can be interpreted in terms of the temperature stability range of the phenolic resin used as a binder of the friction material. The characterization of the collected airborne wear debris showed that the particles produced by the low temperature (i.e., low load) test were mostly equiaxed; whereas those produced by the high temperature (i.e., high loads) tests, predominantly displayed a plate-like morphology. The mechanisms of their formation in relation to the characteristics of the friction layers are illustrated and discussed.
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| 5. |
- Alemani, Mattia, et al.
(författare)
-
Dry sliding of a low steel friction material against cast iron at different loads: characterization of the friction layer and wear debris
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Pin-on-disc testing was used to investigate the sliding behavior and the wear products of a low-steel friction material against a cast iron disc at different applied loads, to investigate the effect of the temperature rise induced by frictional heating. The testing rig was operated in a clean chamber with a purified incoming air flux. The outgoing flux carries the wear particles to an impactor that counted and sorted them by average diameter and weight. At increasing applied loads, corresponding to a proportional increase of the pin-disc contact temperature, the coverage of both the pin and disc surface by a friction layer was found to increase too. The relevant X-Ray diffraction patterns revealed the presence of a large amount of graphite and different compounds originating from the friction material and from the counterface disc, mainly iron oxides, as concerns this latter. After the test at the lowest investigated load, i.e., 1 kg, the disc worn surface exhibited abrasive grooves and a discontinuous friction layer mainly made of compacted iron oxide particles. After the test at higher loads, i.e., 5 and 7 kg, the disc surface was covered by a compact friction layer. As concerns the friction layer on the pins, most of the ingredients from the friction material were detected, in association with the iron oxides from the disc. These results can be interpreted in terms of the temperature stability range of the phenolic resin used as a binder of the friction material. The characterization of the collected airborne wear debris showed that the particles produced by the low temperature (i.e., low load) test were mostly equiaxed; whereas those produced by the high temperature (i.e., high loads) tests, predominantly displayed a plate-like morphology. The mechanisms of their formation in relation to the characteristics of the friction layers are illustrated and discussed.
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| 6. |
- Alemani, Mattia, et al.
(författare)
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On the influence of car brake system parameters on particulate matter emissions
- 2018
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Ingår i: Wear. - : ELSEVIER SCIENCE SA. - 0043-1648 .- 1873-2577. ; 396, s. 67-74
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Tidskriftsartikel (refereegranskat)abstract
- The influence of car brake system parameters on particulate matter emissions was investigated using a pin-on-disc tribometer. Samples from a low-steel friction material and a cast iron disc were tested for different sliding velocities, nominal contact pressures and frictional powers. Disc temperatures were also measured. Their impact on total concentration, size distribution, particle coefficient and transition temperature was analysed. Results show that frictional power is the most significant brake system parameter. However, temperature, as a response parameter, is the most influential, inducing a shift towards the ultrafine particulate fraction and raising emissions. A transition temperature, independent of the system parameters, was identified.
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| 7. |
- Alemani, Mattia, et al.
(författare)
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Scaling effects of measuring disc brake airborne particulate matter emissions – A comparison of a pin-on-disc tribometer and an inertia dynamometer bench under dragging conditions
- 2018
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Ingår i: Proceedings of the Institution of mechanical engineers. Part J, journal of engineering tribology. - : Sage Publications. - 1350-6501 .- 2041-305X. ; 232:12, s. 1538-1547
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Tidskriftsartikel (refereegranskat)abstract
- An important contributor to non-exhaust emissions in urban areas is airborne particulate matter originating from brake systems. A well-established way to test such systems in industry is to use inertia dynamometer benches; although they are quite expensive to run. Pin-on-disc tribometers, on the other hand, are relatively cheap to run, but simplify the real system. The literature indicates promising correlations between these two test stands with regard to measured airborne number distribution. Recent studies also show a strong dependency between the airborne number concentration and the disc temperature. However, a direct comparison that also takes into account temperature effects is missing. The aim of this paper is, therefore, to investigate how the transition temperature is affected by the different test scales, under dragging conditions, and the effects on total concentration and size distribution. New and used low-steel pins/pads were tested against cast iron discs/rotors on both the aforementioned test stands, appositely designed for particulate emission studies. A constant normal load and constant rotational velocity were imposed in both test stands. Results show that a transition temperature can always be identified. However, it is influenced by the test scale and the frictional pair status. Nevertheless, emissions are assessed similarly when an equivalent frictional pair status is analysed (e.g. run-in). Further investigations for fully run-in samples on the pin-on-disc should be performed in order to finally assess the possibility of using the tribometers for the initial assessment of different friction materials.
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| 8. |
- Ali, Nashit, et al.
(författare)
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Friction, wear, and airborne particle emissions from rail-wheel contact with laser cladded overlays-A pin-disc tribometer simulation
- 2023
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Ingår i: Wear. - Amsterdam : Elsevier BV. - 0043-1648 .- 1873-2577. ; 518
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Tidskriftsartikel (refereegranskat)abstract
- The present study uses a pin-on-disc tribometer to evaluate friction, wear, and airborne particle emissions for a rail-wheel contact. Test pins from UIC60 900A rail carbon steels were in contact with three types of test discs surfaces: R7 wheel carbon steel, laser cladding overlayed martensitic stainless steel, and laser cladding overlayed Ni-based-8% MnS self-lubricating alloy. Test results show about halving of the coefficient of friction, 0.42 to 0.22, and one ten-power lower specific pin and disc wear of discs with self-lubricating overlay compared to standard railway carbon steel contacts. Using stainless-steel overlayed discs also resulted in one ten-power lower specific disc wear, but pin wear is unchanged. Particle emission for the tests with discs with self-lubricating overlay is constant at almost 200 particles/cm3 while running in the distance is needed for the other tests. Almost all generated airborne wear particles were in the sub-100 nm range. The use of laser-cladded (LC) overlay reduced the number of airborne wear particles in the sub-100 nm range by more than a factor of 10.
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| 9. |
- Andersson, Martin, et al.
(författare)
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Efficiency and temperature of spray lubricated superfinished spur gears
- 2022
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Ingår i: Proceedings of the Institution of mechanical engineers. Part J, journal of engineering tribology. - : SAGE Publications. - 1350-6501 .- 2041-305X. ; 236:11, s. 2283-2291
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Tidskriftsartikel (refereegranskat)abstract
- Gearboxes are one of the most power dense systems used today, and in certain instances their limiting factor is the ability to evacuate heat from the gear contact. This work analyses the efficiency (i.e. heat generation) and tooth temperature in the three lubricating conditions dip, into mesh spray and out of mesh spray for superfinished gears which are then compared to ground gears. A back-to-back gear test rig is employed to test maximum contact pressures at the pitch of 0.59 to 0.96 GPa and pitch velocities from 0.5 to 20 m/s at a controlled lubricant temperature of 90 °C. The results show superfinished gears have higher mesh efficiency and lower gear tooth and bulk temperatures, hence lower heat flux compared to ground gears in all lubricating conditions.
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| 10. |
- Andersson, Martin, et al.
(författare)
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Efficiency and temperature of spur gears using spray lubrication compared to dip lubrication
- 2017
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Ingår i: Proceedings of the Institution of mechanical engineers. Part J, journal of engineering tribology. - : SAGE PUBLICATIONS LTD. - 1350-6501 .- 2041-305X. ; 231:11, s. 1390-1396
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Tidskriftsartikel (refereegranskat)abstract
- Increased machine efficiency is a requirement in today's world and geared transmissions are no exception. A back-to-back gear test rig was used to compare dip lubrication with spray lubrication regarding gearbox efficiency, mesh efficiency, gear temperature and surface roughness. Gears lubricated at the inlet of the mesh show a lower measured temperature when compared to spray lubrication at the outlet of the mesh. Spray lubrication, when compared to dip lubrication, yields the same efficiency for both rotating directions at the tested speeds of 0.5 to 20 m/s. Spray lubrication shows a significantly higher total gearbox efficiency at higher speeds, higher measured tooth temperature and no measurable change in surface roughness.
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