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1.	Jakobsson, J., et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Journal article (peer-reviewed)
2.	2019 Journal article (peer-reviewed)
3.	Krysko, O, et al. (author) The adjuvant-like activity of staphylococcal enterotoxin B in a murine asthma model is independent of IL-1R signaling 2013 In: Allergy. - : Wiley. - 1398-9995 .- 0105-4538. ; 68:4, s. 446-453 Journal article (peer-reviewed)
4.	Semmrich, Monika, et al. (author) Directed antigen targeting in vivo identifies a role for CD103(+) dendritic cells in both tolerogenic and immunogenic T-cell responses. 2012 In: Mucosal immunology. - : Elsevier BV. - 1935-3456 .- 1933-0219. ; 5:2, s. 150-60 Journal article (peer-reviewed)abstract The αE integrin chain CD103 identifies a subset of migratory dendritic cells (DCs) in the gut, lung, and skin. To gain further understanding of the function of CD103(+) DCs in regulating adaptive immunity in vivo, we coupled ovalbumin (OVA) to the CD103 antibody M290 (M290.OVA). Intraperitoneal injection of M290.OVA induced OVA-specific CD8(+) and CD4(+) T-cell proliferation in lymph nodes (LNs) of wild-type but not CD103(-/-) mice, or in mice depleted of CD11c(+) cells. In the absence of maturation stimuli, systemic antigen targeting to CD103(+) DCs led to tolerance of CD8(+) T cells, whereas coadministration of adjuvant induced cytotoxic T-lymphocyte (CTL) immunity and antibody production. Mucosal intratracheal application of M290.OVA also induced T-cell proliferation in mediastinal LNs, yet the functional outcome was tolerance that inhibited subsequent development of allergic airway inflammation and immunoglobulin E (IgE) responses to inhaled OVA. These findings identify antigen targeting to CD103(+) DCs as a potential strategy to regulate immune responses in nonlymphoid mucosal tissues.

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Liu, X (1); Chen, L (1); Alonso, A. (1); Chen, S. (1); Chen, X. (1); Chen, Y. (1); show more...; Donadelli, M. (1); Gupta, S. (1); Hu, D. (1); Jiang, Y. (1); Jin, S. (1); Kim, H. (1); Kono, T. (1); Li, B. (1); Li, S. (1); Li, Y. (1); Liu, Y. (1); Meyer, C. (1); Mohapatra, S. (1); Nakamura, K. (1); Nilsson, P. (1); Shimizu, S. (1); Takahashi, Y. (1); Wang, C. (1); Wang, F. (1); Wang, H. (1); Wang, J. (1); Wang, K. (1); Wu, M. (1); Xu, L. (1); Yamamoto, A. (1); Yan, Z. (1); Yang, H. (1); Yang, Y. (1); Yu, J. (1); Zhang, H. (1); Zhang, L. (1); Zhang, X. (1); Zhang, Z. (1); Zhou, B. (1); Zhu, H. (1); Liu, J. (1); Zhao, Y. (1); Lange, C. (1); Li, X. (1); Zhao, L. (1); Liu, C. (1); Liu, H. (1); Saito, T (1); Banerjee, S. (1); show less...

University: Lund University (3); Karolinska Institutet (3); University of Gothenburg (2); Stockholm University (2); Umeå University (1); Uppsala University (1); show more...; Halmstad University (1); Linköping University (1); Chalmers University of Technology (1); Swedish University of Agricultural Sciences (1); show less...

Language: English (4)

Research subject (UKÄ/SCB): Medical and Health Sciences (4); Natural sciences (2)

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