| 1. |
- Andersson-Engels, Stefan, et al.
(författare)
-
Identification of brain tumours in rats using laser-induced fluorescence and haematoporphyrin derivative
- 1989
-
Ingår i: Lasers in Medical Science. - 0268-8921. ; 4:4, s. 241-249
-
Tidskriftsartikel (refereegranskat)abstract
- Laser-induced fluorescence has been used for the identification of brain tumours in rats, which have been previously given tumour-seeking haematoporphyrin derivative. A pulsed nitrogen laser (λ=337 nm) was used in conjunction with an optical multichannel analyzer. For both inoculated RG-2 and TCVC rat-brain-tumour models, the blue autofluorescence was strongly reduced in the tumour compared with normal brain tissue, and at the same time the characteristic red-drug signal increased. The contrast between tumour and normal tissue was strongly enhanced by forming the ratio between the two signals. Implications for possible improvement of tumour delineation in brain tumour surgery are discussed.
|
|
| 2. |
- Löfberg, H, et al.
(författare)
-
Occurrence of gamma-trace in the calcitonin-producing C-cells of simian thyroid gland and human medullary thyroid carcinoma
- 1983
-
Ingår i: Acta Endocrinologica. - : Oxford University Press (OUP). - 0001-5598 .- 0804-4643 .- 1479-683X. ; 104:1, s. 69-76
-
Tidskriftsartikel (refereegranskat)abstract
- gamma-Trace, a microprotein occurring in neuroendocrine cells, was demonstrated by immunohistochemical technique to be present in the calcitonin-producing C-cells of normal simian thyroid gland and of human medullary thyroid carcinoma. A comparatively high concentration of gamma-trace was demonstrated in tissue extract of neoplastic C-cells. The immunoreactive protein found in the extract had a molecular weight and electrophoretic mobility characteristic for gamma-trace.
|
|
| 3. |
- Ljung, R, et al.
(författare)
-
Ganglioneuroma with an uncommon location in a six-year-old girl
- 1984
-
Ingår i: Acta Paediatrica Scandinavica. - 0001-656X. ; 73:3, s. 3-411
-
Tidskriftsartikel (refereegranskat)abstract
- A 6-year-old girl with a neurogenic bladder disease is described. Additional gait disturbances and mild but progressive foot deformities led to the diagnosis and surgical treatment of a ganglioneuroma located exclusively intraspinally. It is suggested that the tumor originated from remnant neural crest cells, probably early in life or even prenatally.
|
|
| 4. |
- Löfberg, H, et al.
(författare)
-
gamma-trace in human pituitary adenomas
- 1984
-
Ingår i: The Journal of clinical endocrinology and metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 59:1, s. 8-113
-
Tidskriftsartikel (refereegranskat)abstract
- gamma-Trace, a small protein occurring in body fluids and in secretory and neuroendocrine cells, was demonstrated by immunohistochemical techniques in the cytoplasm of the tumor cells of 13 pituitary adenomas obtained at surgery and autopsy. Seven of the adenomas also contained LH immunoreactivity. FSH, TSH, and ACTH were each found in one gamma-trace-containing adenoma. gamma-Trace was also demonstrated in extracts of 1 pituitary adenoma and of 5 nontumorous adenohypophyses. The immunoreactive protein found in the extracts had a molecular weight and electrophoretic mobility characteristic of gamma-trace. Computerized amino acid sequence comparisons between the primary structure of gamma-trace and those of known hormonal peptides showed no significant similarities.
|
|
