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1.	Baud, A, et al. (author) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats 2013 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:7, s. 767- Journal article (peer-reviewed)
2.	Alam, I, et al. (author) Fine mapping of bone structure and strength QTLs in heterogeneous stock rat 2015 In: Bone. - : Elsevier BV. - 1873-2763 .- 8756-3282. ; 81, s. 417-426 Journal article (peer-reviewed)
3.	Alam, I, et al. (author) Heterogeneous stock rat: a unique animal model for mapping genes influencing bone fragility 2011 In: Bone. - : Elsevier BV. - 1873-2763 .- 8756-3282. ; 48:5, s. 1169-1177 Journal article (peer-reviewed)
4.	Alam, I, et al. (author) High-resolution genome screen for bone mineral density in heterogeneous stock rat 2014 In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. - : Wiley. - 1523-4681. ; 29:7, s. 1619-1626 Journal article (peer-reviewed)
5.	Gimenez-Llort, L, et al. (author) Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain 2007 In: Neurobiology of learning and memory. - : Elsevier BV. - 1074-7427. ; 87:1, s. 42-56 Journal article (peer-reviewed)
6.	Johannesson, M, et al. (author) A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock 2009 In: Genome research. - : Cold Spring Harbor Laboratory. - 1088-9051. ; 19:1, s. 150-158 Journal article (peer-reviewed)abstract The laboratory rat (Rattus norvegicus) is a key tool for the study of medicine and pharmacology for human health. A large database of phenotypes for integrated fields such as cardiovascular, neuroscience, and exercise physiology exists in the literature. However, the molecular characterization of the genetic loci that give rise to variation in these traits has proven to be difficult. Here we show how one obstacle to progress, the fine-mapping of quantitative trait loci (QTL), can be overcome by using an outbred population of rats. By use of a genetically heterogeneous stock of rats, we map a locus contributing to variation in a fear-related measure (two-way active avoidance in the shuttle box) to a region on chromosome 5 containing nine genes. By establishing a protocol measuring multiple phenotypes including immunology, neuroinflammation, and hematology, as well as cardiovascular, metabolic, and behavioral traits, we establish the rat HS as a new resource for the fine-mapping of QTLs contributing to variation in complex traits of biomedical relevance.
7.	Gimenez-Llort, L, et al. (author) Distinct phenotypes of spontaneous activity and induction of amphetamine sensitization in inbred Roman high- and low-avoidance rats: Vulnerability and protection 2018 In: Neuroscience letters. - : Elsevier BV. - 1872-7972 .- 0304-3940. ; 673, s. 92-98 Journal article (peer-reviewed)
8.	Gimenez-Llort, L, et al. (author) Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate 2002 In: The European journal of neuroscience. - : Wiley. - 0953-816X. ; 16:3, s. 547-550 Journal article (peer-reviewed)
9.	Gimenez-Llort, L, et al. (author) Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly 2005 In: Synapse (New York, N.Y.). - : Wiley. - 0887-4476 .- 1098-2396. ; 57:1, s. 8-16 Journal article (peer-reviewed)
10.	Gimenez-Llort, L, et al. (author) Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid 2007 In: Neuroscience and biobehavioral reviews. - : Elsevier BV. - 0149-7634. ; 31:1, s. 125-147 Journal article (peer-reviewed)

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Result 1-10 of 15

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Type of publication: journal article (14); conference paper (1)

Type of content: peer-reviewed (14); other academic/artistic (1)

Author/Editor: Tobena, A (15); Fernandez-Teruel, A (14); Canete, T (10); Johansson, B (8); Blazquez, G (6); Diez, M (5); show more...; Lopez-Aumatell, R (5); Martinez-Membrives, ... (5); Johannesson, M (5); Olsson, T (4); Terenius, L (4); Alam, I (4); Koller, DL (4); Stridh, P (4); Foroud, T (4); Flint, J (3); Diaz-Moran, S (3); Baud, A (3); Econs, MJ (3); Vicens-Costa, E (3); Graham, D. (2); Ockinger, J (2); Holmdahl, R (2); Ogren, SO (2); Fredholm, BB (2); Beyeen, AD (2); Gauguier, D (2); Mont-Cardona, C (2); Schulz, H. (1); Diaz, S (1); Abdelmagid, N (1); Jagodic, M (1); Hubner, N. (1); Lathrop, M (1); Martinez, E (1); Halldner, L (1); Gillett, A (1); Fuxe, K (1); FERRE, S (1); Ciruela, F (1); Franco, R (1); Lluis, C (1); Aitman, TJ (1); Cuppen, E (1); Dominiczak, A (1); Saar, K (1); Guerreiro-Cacais, AO (1); Sun, QW (1); Roeder, RK (1); Mont, C (1); show less...

University: Karolinska Institutet (15)

Language: English (15)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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