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Sökning: WFRF:(Wennström Jan 1947)

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1.
  • Derks, Jan, 1977, et al. (författare)
  • Effectiveness of implant therapy analyzed in a Swedish population: Early and late implant loss
  • 2015
  • Ingår i: Journal of Dental Research. - : SAGE Publications. - 0022-0345 .- 1544-0591. ; 94
  • Tidskriftsartikel (refereegranskat)abstract
    • Treatment outcomes in implant dentistry have been mainly assessed as implant survival rates in small, selected patient groups of specialist or university clinical settings. This study reports on loss of dental implants assessed in a large and randomly selected patient sample. The results were aimed at representing evaluation of effectiveness of implant dentistry. Using the national data register of the Swedish Social Insurance Agency, 4,716 patients were randomly selected. All had been provided with implant-supported restorative therapy in 2003. Patient files of 2,765 patients (11,311 implants) were collected from more than 800 clinicians. Information on patients, treatment procedures, and outcomes related to the implant-supported restorative therapy was extracted from the files. In total, 596 of the 2,765 subjects, provided with 2,367 implants, attended a clinical examination 9 y after therapy. Implant loss that occurred prior to connection of the supraconstruction was scored as an early implant loss, while later occurring loss was considered late implant loss. Early implant loss occurred in 4.4% of patients (1.4% of implants), while 4.2% of the patients who were examined 9 y after therapy presented with late implant loss (2.0% of implants). Overall, 7.6% of the patients had lost at least 1 implant. Multilevel analysis revealed higher odds ratios for early implant loss among smokers and patients with an initial diagnosis of periodontitis. Implants shorter than 10 mm and representing certain brands also showed higher odds ratios for early implant loss. Implant brand also influenced late implant loss. Implant loss is not an uncommon event, and patient and implant characteristics influence outcomes
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2.
  • Derks, Jan, 1977, et al. (författare)
  • Effectiveness of Implant Therapy Analyzed in a Swedish Population: Prevalence of Peri-implantitis
  • 2016
  • Ingår i: Journal of Dental Research. - : SAGE Publications. - 0022-0345 .- 1544-0591. ; 95:1, s. 43-49
  • Tidskriftsartikel (refereegranskat)abstract
    • Peri-implantitis is an inflammatory disease affecting soft and hard tissues surrounding dental implants. As the global number of individuals that undergo restorative therapy through dental implants increases, peri-implantitis is considered as a major and growing problem in dentistry. A randomly selected sample of 588 patients who all had received implant-supported therapy 9 y earlier was clinically and radiographically examined. Prevalence of peri-implantitis was assessed and risk indicators were identified by multilevel regression analysis. Forty-five percent of all patients presented with peri-implantitis (bleeding on probing/suppuration and bone loss >0.5 mm). Moderate/severe peri-implantitis (bleeding on probing/suppuration and bone loss >2 mm) was diagnosed in 14.5%. Patients with periodontitis and with >= 4 implants, as well as implants of certain brands and prosthetic therapy delivered by general practitioners, exhibited higher odds ratios for moderate/severe peri-implantitis. Similarly, higher odds ratios were identified for implants installed in the mandible and with crown restoration margins positioned <= 1.5 mm from the crestal bone at baseline. It is suggested that peri-implantitis is a common condition and that several patient-and implant-related factors influence the risk for moderate/severe peri-implantitis (ClinicalTrials.gov NCT01825772).
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3.
  • Derks, Jan, 1977, et al. (författare)
  • Patient-reported outcomes of dental implant therapy in a large randomly selected sample
  • 2015
  • Ingår i: Clinical Oral Implants Research. - : John Wiley & Sons. - 0905-7161 .- 1600-0501. ; 26:5, s. 586-591
  • Tidskriftsartikel (refereegranskat)abstract
    • BackgroundIn addition to traditional clinical parameters, the need to include patient-reported assessments into dental implant research has been emphasized. AimThe aim of this study was to evaluate patient-reported outcomes following implant-supported restorative therapy in a randomly selected patient sample. Material and MethodsFour thousand seven hundred and sixteen patients were randomly selected from the data register of the Swedish Social Insurance Agency. A questionnaire containing 10 questions related to implant-supported restorative therapy was mailed to each of the individuals about 6years after therapy. Associations between questionnaire data, and (i) patient-related, (ii) clinician-related and (iii) therapy-related variables were identified by multivariate analyses. ResultsThree thousand eight hundred and twenty-seven patients (81%) responded to the questionnaire. It was demonstrated that the overall satisfaction among patients was high. Older patients presented with an overall more positive perception of the results of the therapy than younger patients and males were more frequently satisfied in terms of esthetics than females. While clinical setting did not influence results, patients treated by specialist dentists as opposed to general practitioners reported a higher frequency of esthetic satisfaction and improved chewing ability. In addition, patients who had received extensive implant-supported reconstructions, in contrast to those with small reconstructive units, reported more frequently on improved chewing ability and self-confidence but also to a larger extent on implant-related complications. ConclusionIt is suggested that patient-perceived outcomes of implant-supported restorative therapy are related to (i) age and gender of the patient, (ii) the extent of restorative therapy and (iii) the clinician performing the treatment.
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4.
  • Derks, Jan, 1977, et al. (författare)
  • Peri-implantitis - onset and pattern of progression.
  • 2016
  • Ingår i: Journal of clinical periodontology. - : Wiley. - 1600-051X .- 0303-6979. ; 43:4, s. 383-388
  • Tidskriftsartikel (refereegranskat)abstract
    • While information on the prevalence of peri-implantitis is available, data describing onset and progression of the disease are limited.
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5.
  • Karlsson, Karolina, 1975, et al. (författare)
  • Interventions for peri-implantitis and their effects on further bone loss: A retrospective analysis of a registry-based cohort
  • 2019
  • Ingår i: Journal of Clinical Periodontology. - : Wiley. - 0303-6979 .- 1600-051X. ; 46:8, s. 872-879
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective The aim of the present study was to assess interventions and their consequences with regard to further bone loss at sites diagnosed with peri-implantitis. Materials and Methods In 2017, records of 70 patients diagnosed with moderate/severe peri-implantitis at >= 1 implant sites 4 years earlier were obtained. Changes of marginal bone levels during the study period assessed on radiographs and predictors of disease progression were identified by Cox regression and mixed linear modelling. Patient files were analysed for professional interventions related to the treatment of peri-implantitis. Results Mean bone loss (+/- SD) at implants diagnosed with moderate/severe peri-implantitis was 1.1 +/- 2.0 mm over the observation period of 3.3 years. While non-surgical measures including submucosal and/or supra-mucosal cleaning of implants were provided to almost all patients, surgical treatment of peri-implantitis was limited to a subgroup (17 subjects). Surgically treated implant sites demonstrated a mean bone loss of 1.4 +/- 2.4 mm prior to surgical intervention, while only minor changes (0.2 +/- 1.0 mm) occurred after therapy. Clinical parameters (bleeding/suppuration on probing and probing depth) assessed at diagnosis were statistically significant predictors of disease progression. Conclusions Non-surgical procedures were insufficient to prevent further bone loss at implant sites affected by moderate/severe peri-implantitis. Surgical treatment of peri-implantitis markedly diminished the progression of bone loss. Clinical assessments of bleeding on probing and probing depth at diagnosis predicted further bone loss.
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6.
  • Karlsson, Karolina, 1975, et al. (författare)
  • Technical complications following implant-supported restorative therapy performed in Sweden
  • 2018
  • Ingår i: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 29:6, s. 603-611
  • Tidskriftsartikel (refereegranskat)abstract
    • ObjectiveThe aim of this study was to evaluate the occurrence and consequences of technical complications in implant-supported restorative therapy. Material & MethodsThe occurrence and consequences of technical complications in implant-supported restorative therapy over a mean follow-up period of 5.3years were assessed based on documentation in files from 2,666 patients. Risk indicators were identified by the use of survival models, considering repeated events. Results were expressed as hazard ratios (HR) including 95% confidence intervals. ResultsTechnical complications occurred in 24.8% of the patients. Chipping and loss of retention were the most common, affecting 11.0% and 7.9% of supraconstructions, respectively, while implant-related complications (e.g., implant fracture) were rare. More than 50% of the affected patients experienced technical complications more than once and almost all reported complications led to interventions by a dental professional. The extent of the supraconstruction was the strongest risk indicator for both chipping (HR<0.2) and loss of retention (HR>3). ConclusionOver a 5-year period, technical complications in implant-supported restorative therapy occurred frequently and their management required professional intervention.
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7.
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8.
  • Araújo, Mauricio G, et al. (författare)
  • Modeling of the buccal and lingual bone walls of fresh extraction sites following implant installation.
  • 2006
  • Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 17:6, s. 606-14
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: To determine whether the reduction of the alveolar ridge that occurs following tooth extraction and implant placement is influenced by the size of the hard tissue walls of the socket. MATERIAL AND METHODS: Six beagle dogs were used. The third premolar and first molar in both quadrants of the mandible were used. Mucoperiostal flaps were elevated and the distal roots were removed. Implants were installed in the fresh extraction socket in one side of the mandible. The flaps were replaced to allow a semi-submerged healing. The procedure was repeated in the contra later side of the mandible after 2 months. The animals were sacrificed 1 month after the final implant installation. The mandibles were dissected, and each implant site was removed and processed for ground sectioning. RESULTS: Marked hard tissue alterations occurred during healing following tooth extraction and implant installation in the socket. The marginal gap that was present between the implant and the walls of the socket at implantation disappeared as a result of bone fill and resorption of the bone crest. The modeling in the marginal defect region was accompanied by marked attenuation of the dimensions of both the delicate buccal and the wider lingual bone wall. Bone loss at molar sites was more pronounced than at the premolar locations. CONCLUSION: Implant placement failed to preserve the hard tissue dimension of the ridge following tooth extraction. The buccal as well as the lingual bone walls were resorbed. At the buccal aspect, this resulted in some marginal loss of osseointegration.
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9.
  • Araújo, Mauricio G, 1966, et al. (författare)
  • Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog.
  • 2005
  • Ingår i: Journal of clinical periodontology. - 0303-6979. ; 32:6, s. 645-52
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: To study dimensional alterations of the alveolar ridge that occurred following implant placement in fresh extraction sockets. MATERIAL AND METHODS: Five beagle dogs were included in the study. In both quadrants of the mandible, incisions were made in the crevice region of the third and fourth pre-molars. Buccal and minute lingual full-thickness flaps were elevated. The mesial root of the four pre-molars root was filled and the teeth were hemi-sected. Following flap elevation in (3)P(3) and (4)P(4) regions, the distal roots were removed. In the right jaw quadrants, implants with a sand blasted and acid etched (SLA) surface were placed in the fresh extraction sockets, while in the left jaws the corresponding sockets were left for spontaneous healing. The mesial roots were retained as surgical control teeth. After 3 months, the animals were examined clinically, sacrificed and tissue blocks containing the implant sites, the adjacent tooth sites (mesial root) and the edentulous socket sites were dissected, prepared for ground sectioning and examined in the microscope. RESULTS: At implant sites, the level of bone-to-implant contact (BC) was located 2.6+/-0.4 mm (buccal aspect) and 0.2+/-0.5 mm (lingual aspect) apical of the SLA level. At the edentulous sites, the mean vertical distance (V) between the marginal termination of the buccal and lingual bone walls was 2.2+/-0.9 mm. At the surgically treated tooth sites, the mean amount of attachment loss was 0.5+/-0.5 mm (buccal) and 0.2+/-0.3 mm (lingual). CONCLUSIONS: Marked dimensional alterations had occurred in the edentulous ridge after 3 months of healing following the extraction of the distal root of mandibular pre-molars. The placement of an implant in the fresh extraction site obviously failed to prevent the re-modelling that occurred in the walls of the socket. The resulting height of the buccal and lingual walls at 3 months was similar at implants and edentulous sites and vertical bone loss was more pronounced at the buccal than at the lingual aspect of the ridge. It is suggested that the resorption of the socket walls that occurs following tooth removal must be considered in conjunction with implant placement in fresh extraction sockets.
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10.
  • Araújo, Mauricio G, 1966, et al. (författare)
  • The influence of Bio-Oss collagen on healing of an extraction socket: An experimental study in the dog.
  • 2008
  • Ingår i: The International Journal of Periodontics & Restorative Dentistry. - 0198-7569. ; 28:2, s. 123-135
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Different approaches were advocated to preserve or improve the dimension and contour of the ridge following tooth extraction. In some of studies socket grafting apparently had a successful outcome while in other reports the benefits of such therapy were more questionable. Aim: The objective of the present experiment was to evaluate the effect on hard tissue modeling and remodeling of the placement of a xenograft in the fresh extraction socket in dogs. Material and Methods: Five mongrel dogs were used. Two mandibular premolars (4P4) were hemi-sected. The distal roots were carefully removed. In one socket, a graft consisting of Bio-Oss® Collage was placed while the contra-lateral site was left without grafting. After 3 months of healing, the dogs were euthanized and biopsies sampled. From each experimental site, 4 ground sections – 2 from the mesial root and 2 from the healed socket – were prepared, stained and examined in the microscope. Results: The placement of Bio-Oss® Collagen in the fresh extraction socket failed to inhibit the processes of modeling and remodeling that took place in the socket walls following tooth extraction. The biomaterial, however, apparently promoted de novo hard tissue formation, in particular in the cortical region of the extraction site. Hereby, the dimension of the hard tissue was maintained and the profile of the ridge was better preserved. Conclusion: The placement of a biomaterial in an extraction socket may promote bone modeling and at least temporarily compensate for marginal ridge contraction.
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