| 1. |
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| 2. |
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1973. En träff med tidsandan
- 2008
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Ingår i: 1973. En träff med tidsandan. - Lund : Nordic Academic Press. - 9789189116979 ; , s. 11-21
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)
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| 3. |
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2-(p-Hydroxybenzyl)indoles - Side Products Formed Upon Cleavage of Indole Derivatives from Carboxylated Wang Polymer - an NMR Study.
- 2003
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Ingår i: molecules. ; 8:10, s. 728-734
-
Tidskriftsartikel (refereegranskat)abstract
- Treatment of carboxylated Wang polymer attached to a 2-unsubstituted indole derivative with a trifluoroacetic acid based mixture resulted in a side reaction: p-hydroxybenzylation at the 2-position of the indole ring. The structure of the resulting N-3- aminopropyl)-N-benzyl-4-[2-(4-hydroxybenzyl)-1H-indol-3-yl]-butyramide trifluoroacetate was ascertained by a full assignment of its 1H- and 13C-NMR spectra. The side reaction could be suppressed by the use of 1,2-ethanedithiol in high concentrations (16 %).
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| 11. |
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| 13. |
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7th International Workshop on Automotive System/Software Architecture (WASA 2021)
- 2021
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Proceedings (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- This volume contains the papers presented at the 7th International Workshop on Automotive System/Software Architecture (WASA 2021) held on March 22, 2021, in Stuttgart, Germany. WASA was organized as part of the 18th IEEE International Conference on Software Architecture (ICSA 2021), the premier software architecture conference. Due to the worldwide SARS-CoV-2 pandemic, the main conference and the workshop were hosted virtually.
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| 14. |
- A. Bateki, Christian, et al.
(författare)
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Of milk and mobiles: Assessing the potential of cellphone applications to reduce cattle milk yield gaps in Africa using a case study
- 2021
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Ingår i: Computers and Electronics in Agriculture. - : Elsevier BV. - 0168-1699. ; 191
-
Tidskriftsartikel (refereegranskat)abstract
- There are growing expectations that Information and Communication Technology (ICT) applications could help improve on-farm yields amongst smallholder farmers in developing countries, and consequently, food and nutrition security. However, few studies have quantified the actual contribution of ICT applications on farmers’ yields, and these studies predominantly focused on crop production. We assessed the potential of ICT applications to close milk yield gaps among small- and medium scale dairy cattle farmers in Africa. First, we developed a theoretical framework summarizing biophysical and socio-economic constraints that foster milk yield gaps and discussed which constraints can be addressed using ICT applications. Second, using a case study of a feeding advice application for dairy cattle pre-tested with farmers in rural Kenya, we analyzed how much stand-alone the application could contribute to close dairy cattle milk yield gaps. Our findings suggest that ICT applications could help address some existing biophysical and socio-economic constraints fostering milk yield gaps, including data collection for breeding programs, feeding management advice, and facilitating access to markets and capital. Our stand-alone ICT application closed yield gaps by 2 % to 6 % on representative farms. Several factors may explain the limited actual contribution of selected ICT applications to reduce existing milk yield gaps, including the quality of the input data and models used in ICT applications, and more structural constraints that cannot be addressed by digital tools. Therefore, although ICT applications could help address constraints to achieving higher milk yields on dairy farms, a significant contribution to improve yields may only be achieved when conditions surrounding their use are adequate.
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| 15. |
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A City Curating Reader - Public Art Munich 2018
- 2018
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- What is public in public art? What are the contingencies of working outside of the protection of the institutional walls? What makes city curating? This reader takes Munich as a case study, and documents the projects of Public Art Munich 2018 dealing with political, ideological and economical shifts, spanning from the founding of the Bavarian Soviet Republic in 1919 to the arrival of refugees at the Hauptbahnhof in 2015. The book contextualizes art within the broader questions of the grammar of the public sphere and of what constitutes publicness today. It also reflects on the concept of context-specific city curating, performativity and art conceived in minutes rather than square meters. Art projects, conversations and essays plot a narrative of how art can cultivate encounters with the unpredictable, negotiate uncommonness, and provoke counter-publics to come. The reader is published on the occasion of Public Art Munich 2018 – Game Changers (April 30-July 27, 2018), curated by Joanna Warsza.
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| 16. |
- A, Dell'Isola, et al.
(författare)
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The role of pain and walking difficulties in shaping willingness to undergo joint surgery for osteoarthritis: Data from the Swedish BOA register
- 2021
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Ingår i: Osteoarthritis and Cartilage Open. - : Elsevier BV. - 2665-9131. ; 3:2
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives: To investigate whether the association between pain intensity and willingness to undergo surgery is explained by walking difficulties, in patients with knee or hip osteoarthritis (OA). Methods: This is an observational study using data from the Better management of patients with Osteoarthritis (BOA) register, which collects data from a publicly financed self-management programme for people with OA in Sweden. We included all patients with knee or hip OA who attended the baseline visit between 2008 and 2016. We conducted separate mediation analyses within a counterfactual framework to estimate the mediation effect of walking difficulties (yes/no) on willingness to undergo surgery (yes/no) for each one-point increase in pain (0–10 on a numeric rating scale), adjusted for relevant confounders. Results: We included 72,131 patients (69% women, mean age 66, mean pain 5.4, 81% had walking difficulties, 27% was willing to undergo surgery). A one-point increase in pain intensity was associated with 1.53 (95% CI: 1.51; 1.55) higher odds of being willing to undergo surgery. Walking difficulties mediated 10%–25% of the effect of one-point increase in pain when pain was <8/10, while at pain ≥8/10 this percentage decreased to 3%. Conclusions: More than 80% of the BOA patients have mild to moderate pain (<8/10) and walking difficulties can mediate up to a quarter of the total effect of pain on the willingness to undergo surgery in these patients. Trials to evaluate the potential to lower surgery demand by reducing walking difficulties in people with these characteristics are needed.
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| 17. |
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| 18. |
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A HISTORY OF BUSINESS CARTELS - INTERNATIONAL POLITICS, NATIONAL POLICIES AND ANTI-COMPETITIVE BEHAVIOUR
- 2022
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- International cartels are powerful organizations that impact our everyday lives, although they are little known. This book presents 15 historical case studies of international cartels that include agricultural and mineral commodities, the machinery industry, telephone equipment, whiskey and cement. These cases reveal that international cartels manipulated prices and shared markets over many decades but that their real impact was far wider. The global convergence towards criminalizing serious cartel conduct has seen a revival in historical research on cartels and competition policy. The regulation of anti-competitive behaviour has changed over time. To understand why the US, European and other modern economies altered their policies through the 20th century, it is critical to understand when, how and why governments have interacted with, and been influenced by, business organizations such as cartels. This volume draws together researchers from different nations to examine the impact of international cartels on the experience of individual nations, those nations’ interactions with one or more international cartels, and ultimately the interactions of individual nations with the wider international community. This book will be of interest to researchers, academics and advanced students in the fields of business and economic history, political economy, and government policy, as well as those interested in cartels and their impact on the wider economy.
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| 19. |
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A History of National Museums in Europe 1750-2010: Mobilization and Legitimacy, Continuity and Change.
- 2015
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- National Museums and Nation-building in Europe 1750–2010 is placed at the heart of the intersection where the socio-political and the scientific logics meet in the context of nation-building, representing and legitimizing nations in and through national museums. National museums and their representations have therefore within a world of nations become an international standard of nation-claiming and nation-branding. We approach the study of national museums as a historic and contemporary process of institutionalized negotiations of dominant values that constitute a basis for national communities and dynamic state formations. The national museum is thus a knowledge-based socio-political institution, with corresponding collections and displays that ultimately claim, articulate and represent dominant national values and myths. National Museums and Nation-building in Europe 1750–2010 will respond to basic questions about the establishment and dynamics of national museums by investigating the trajectory, context and timing of their establishment. It will also answer more complex questions. To what extent and with what consequences do the trajectory and timing of nation- and state-making processes interact with museum initiatives, creations, societal challenges and justifications?
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| 20. |
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A history of Swedish broadcasting : communicative ethos, genres and institutional change / edited by Monika Djerf-Pierre & Mats Ekström
- 2013
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Broadcast communication has had a profound effect on modern society in the 20th and early 21st centuries. A growing international field of research has examined the historical development of broadcasting within various social and historical contexts, but also has made significant contributions to the understanding of media communication in general. Central topics in this discussion concern the relationships between technological innovations, institutional arrangements, social relations and culture. This book analyses the historical developments of Swedish broadcasting from the introduction of radio in the mid-1920s until the early 2000s. In relation to international research, it explores key aspects of how broadcast media emerged as a way to communicate over distance, connected to audiences, and evolved into central institutions and socio-cultural universes in society. The chapters are arranged in five thematic sections focusing on the invention and early development of radio and television, audience orientation, professional practices, broadcast genres, and institutional changes. The book derives from a large-scale research programme on Swedish broadcast history comprising about 50 studies and led by the “Swedish Foundation of Broadcast Media History”.
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| 21. |
- A, Komonen, et al.
(författare)
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Insects associated with fruit bodies of the wood-decaying fungus Oak mazegill (Daedalea quercina) in mixed oak forests in southern Sweden
- 2012
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Ingår i: Entomologisk Tidskrift. - 0013-886X. ; 133:4, s. 173-181
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Tidskriftsartikel (refereegranskat)abstract
- Polypores host species rich insect assemblages, but relatively few polypore species have been studied in detail. We investigated insect assemblages associated with the fruit bodies of Daedalea quercina, a specialist species on oak in southern Sweden. Fruit bodies (n = 228) were collected from 25 nature reserves and woodland key habitats, and were taken into the laboratory to collect emerging insects. A total of 245 insect individuals were recorded, belonging to at least 45 species. The numerically dominant fungivores were the tineid moths Montescardia tessulatella (n = 38 individuals) and Nemapogon fungivorellus (n = 10) and the coleopteran Ennearthron cornutum (Ciidae) (n = 44). Altogether 40 individuals of hymenopteran parasitoids were recorded, belonging to Braconidae (Exothecinae, Microgastrinae and Rogadinae, altogether 6 spp.), Ichneumonidae (Banchinae, Cryptinae and Orthocentrinae, altogether 4 spp.), Torymidae (1 sp.), Perilampidae (1 sp.) and Scelionidae (1 sp.). Most of the remaining insect species are not specifically associated with fruit bodies, but occupy many types of decaying material. In conclusion, D. quercina hosted a low number of insect individuals in general and only a few coleopteran species. The fungus apparently has only one specialist species, N. fungivorellus, which is a near-threatened (NT) species on the Swedish red list; the record from Norra Vi is the first from the Jönköping. The overall low number of insect individuals and the dominance of Lepidoptera among the fungivores is possibly explained by the tough fruit bodies of D. quercina, which only moths are able to utilize; fruit bodies which had already started to rot were devoid of moths.
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| 22. |
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| 23. |
- A. Nojima,, et al.
(författare)
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Calculational aspects of electron-phonon coupling at surfaces
- 2008
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Ingår i: J. Phys: Condens. Matter. - : IOP Publishing. - 1361-648X .- 0953-8984. ; 20
-
Tidskriftsartikel (refereegranskat)abstract
- We study the validity of two frequently used approximations in calculations of electron–phonon coupling at surfaces. The rigid-ion approximation is a standard approximation used for the bulk metals. On the basis of density functional theory calculations, we find that for Be this approximation is as valid for surface atoms as for bulk atoms. In addition, the slab method for calculations of a phonon induced surface state lifetime is examined. The convergence of the electron–phonon matrix element with respect to the thickness of the slab is studied for several systems. When the number of slab layers is increased, the net effect of decreasing overlap and increasing number of final states depends strongly on the decay length of the surface state wavefunction and the band structure.
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| 24. |
- A. Nojima,, et al.
(författare)
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Model Eliashberg function for surface states
- 2008
-
Ingår i: Applied Surface Science. ; 254:23
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Tidskriftsartikel (refereegranskat)abstract
- We present a simplified procedure for the analysis of the phonon-induced lifetimes of surface states. The model includes information about the electron and phonon structure and is thus more reliable than procedures based on phonon Debye models. We apply the model to calculate the lifetime broadening of Cu(1 1 1) and Al(0 0 1) surface states. The obtained Eliashberg functions and lifetimes are in reasonable agreement with previous detailed studies.
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| 25. |
- A.O., Tillmar, et al.
(författare)
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Using X-chromosomal markers in relationship testing: Calculation of likelihood ratios taking both linkage and linkage disequilibrium into account
- 2011
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Ingår i: Forensic Science International: Genetics. - : Elsevier BV. - 1872-4973 .- 1878-0326. ; 5:5, s. 506-511
-
Tidskriftsartikel (refereegranskat)abstract
- X-chromosomal markers in forensic genetics have become more widely used during recent years, particularly for relationship testing. Linkage and linkage disequilibrium (LD) must typically be accounted for when using close X-chromosomal markers. Thus, when producing the weight-of-evidence, given by a DNA-analysis with markers that are linked, the normally used product rule is invalid. Here we present an implementation of an efficient model for calculating likelihood ratios (LRs) with markers on the X-chromosome which are linked and in LD. Furthermore, the model was applied on several cases based on data from the eight X-chromosomal loci included in the Mentype® Argus X-8 (Biotype). Using a simulation approach we showed that the use of X-chromosome data can offer valuable information for choosing between the alternatives in each of the cases we studied, and that the LR can be high in several cases. We demonstrated that when linkage and LD were disregarded, as opposed to taken into account, the difference in calculated LRs could be considerable. When these differences were large, the estimated haplotype frequencies often had a strong impact and we present a method to estimate haplotype frequencies. Our conclusion is that linkage and LD should be accounted for when using the tested set of markers, and the used model is an efficient way of doing so.
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| 26. |
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A place to live : gender research on housing in Africa
- 1996
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Be it a house or a makeshift, a shared or rented room, or a home of one's own, a place to live is central in surviving strategies of all urban households. In this volume the authors explore the gendered experiences of housing and housing rights in African countries. There are many differences but also many similarities in the pattern of women not having the same access and control over housing as men have. While women often are the bread-winners, they are also the home-makers, in the sense that it is women who put intense efforts in making a place home.
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| 27. |
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A Research Agenda for Management and Organization Studies
- 2016
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Managing and organizing are now central phenomena in contemporary societies. It is essential they are studied from a variety of perspectives, and with equal attention paid to their past, their present, and their future. This book collects opinions of the trailblazing scholars concerning the most important research topics, essential for study in the next 15–20 years. The opinions concern both traditional functions, such as accounting and marketing, personnel management and strategy, technology and communication, but also new challenges, such as diversity, equality, waste and cultural encounters. The collection is intended to be inspiration for young scholars and an invitation to a dialogue with practitioners.
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| 28. |
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| 29. |
- A, Teschendorff, et al.
(författare)
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The dynamics of DNA methylation covariation patterns in carcinogenesis
- 2014
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Ingår i: PLoS Computational Biology. - : Public Library of Science (PLoS). - 1553-734X .- 1553-7358. ; 10:7
-
Tidskriftsartikel (refereegranskat)abstract
- Recently it has been observed that cancer tissue is characterised by an increased variability in DNA methylation patterns. However, how the correlative patterns in genome-wide DNA methylation change during the carcinogenic progress has not yet been explored. Here we study genome-wide inter-CpG correlations in DNA methylation, in addition to single site variability, during cervical carcinogenesis. We demonstrate how the study of changes in DNA methylation covariation patterns across normal, intra-epithelial neoplasia and invasive cancer allows the identification of CpG sites that indicate the risk of neoplastic transformation in stages prior to neoplasia. Importantly, we show that the covariation in DNA methylation at these risk CpG loci is maximal immediately prior to the onset of cancer, supporting the view that high epigenetic diversity in normal cells increases the risk of cancer. Consistent with this, we observe that invasive cancers exhibit increased covariation in DNA methylation at the risk CpG sites relative to normal tissue, but lower levels relative to pre-cancerous lesions. We further show that the identified risk CpG sites undergo preferential DNA methylation changes in relation to human papilloma virus infection and age. Results are validated in independent data including prospectively collected samples prior to neoplastic transformation. Our data are consistent with a phase transition model of carcinogenesis, in which epigenetic diversity is maximal prior to the onset of cancer. The model and algorithm proposed here may allow, in future, network biomarkers predicting the risk of neoplastic transformation to be identified.
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| 30. |
-
A-Z of Gravity's End - Your Ultimate Guide to Free Fall and Levitation
- 2019
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- How did the Tibetan monks levitate heavy boulders? What is barophobia and who was Qamar Ali? How did Ann Hodges' life turn out, the only human on earth hit by a meteorite? This book is more than simply a guide or glossary, it responds to the colossal themes of levitation and free fall through an artistic lens. It contains scientific, artistic and mystical examples, reflections and fictional stories by different authors on the phenomena and history of gravity, weightlessness, levitation and their antithesis: the art of falling. It is a collage, a summary of the artists own experiments and investigations, that will take the reader on a journey that straddles the fictional and the real. The book contains stories in which for example humans, frogs and objects are capable of floating freely through space, be it through magic, cheap tricks, advanced technology or other, more imaginative methods. Contributors: Aaron Schuster, Pamela Jaskoviak, Mikael Lövgren and Ann-Charlotte Glasberg Blomqvist
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| 31. |
- Aaberge, Rolf, et al.
(författare)
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Evaluation of an In-work Tax Credit Reform in Sweden: Effects on Labor Supply and Welfare Participation of Single Mothers
- 2008
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this paper is to evaluate a recent Swedish in-work tax credit reform where we pay particular attention to labor market exclusion; i.e. individuals in as well as outside the labor force are included in the analysis. To highlight the importance of the joint effects from the tax and the benefit systems it appears particular relevant to analyze the labor supply behavior of single mothers. To this end, we estimate a structural microeconometric model of labor supply and welfare participation. The model accounts for heterogeneity in consumption-leisure preferences as well as for constraints in job opportunities. The results of the evaluation show that the reform generates welfare-gains for virtually every single mother, and moreover benefits low-income households. Finally, due to increased labor supply and decline in welfare participation we find that this reform is almost self-financing.
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| 32. |
- Aaberge, Rolf, et al.
(författare)
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U.S. versus Sweden: The Effect of Alternative In-Work Tax Credit Policies on Labour Supply of Single Mothers
- 2013
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- An essential difference between the design of the Swedish and the US in-work tax credit systems relates to their functional forms. Where the US earned income tax credit (EITC) is phased out and favours low and medium earnings, the Swedish system is not phased out and offers 17 and 7 per cent tax credit for low and medium low incomes and a lump-sum tax deduction equal to approximately 2300 USD for medium and higher incomes. The purpose of this paper is to evaluate the efficiency and distributional effects of these two alternative tax credit designs. We pay particular attention to labour market exclusion; i.e. individuals within as well as outside the labour force are included in the analysis. To highlight the importance of the joint effects from the tax and the benefit systems it appears particular relevant to analyse the labour supply behaviour of single mothers. To this end, we estimate a structural random utility model of labour supply and welfare participation. The model accounts for heterogeneity in consumption-leisure preferences as well as for heterogeneity and constraints in job opportunities. The results of the evaluation show that the Swedish system without phase-out generates substantial larger labour supply responses than the US version of the tax credit. Due to increased labour supply and decline in welfare participation we find that the Swedish reform is self-financing for single mothers, whereas a 10 per cent deficit follows from the adapted EITC version used in this study. However, where income inequality rises modestly under the Swedish tax credit system, the US version with phase-out leads to a significant reduction in the income inequality.
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| 33. |
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| 34. |
- Aaen, J., et al.
(författare)
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Clinical and MRI findings in lumbar spinal stenosis: baseline data from the NORDSTEN study
- 2022
-
Ingår i: European Spine Journal. - : Springer Science and Business Media LLC. - 0940-6719 .- 1432-0932. ; 31:6, s. 1391 - 1398
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose The aim was to describe magnetic resonance imaging findings in patients planned for lumbar spinal stenosis surgery. Further, to describe possible associations between MRI findings and patient characteristics with patient reported disability or pain. Methods The NORDSTEN spinal stenosis trial included 437 patients planned for surgical decompression of LSS. The following MRI findings were evaluated before surgery: morphological (Schizas) and quantitative (cross-sectional area) grade of stenosis, disk degeneration (Pfirrmann), facet joint tropism and fatty infiltration of the multifidus muscle. Patients were dichotomized into a moderate or severe category for each radiological parameter classification. A multivariable linear regression analysis was performed to investigate the association between MRI findings and preoperative scores for Oswestry Disability Index, Zurich Claudication Questionnaire and Numeric rating scale for back and leg pain. The following patient characteristics were included in the analysis: gender, age, smoking and weight. Results The percentage of patients with severe scores was as follows: Schizas (C + D) 71.3%, cross-sectional area (< 75 mm(2)) 86.8%, Pfirrmann (4 + 5) 58.1%, tropism (>= 15 degrees) 11.9%, degeneration of multifidus muscle (2-4) 83.7%. Regression coefficients indicated minimal changes in severity of symptoms when comparing the groups with moderate and severe MRI findings. Only gender had a significant and clinically relevant association with ODI score. Conclusion In this cross-sectional study, the majority of the patients had MRI findings classified as severe LSS changes, but the findings had no clinically relevant association with patient reported disability and pain at baseline. Patient characteristics have a larger impact on disability and pain than radiological findings.
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| 35. |
- Aaen, J., et al.
(författare)
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Is the presence of foraminal stenosis associated with outcome in lumbar spinal stenosis patients treated with posterior microsurgical decompression
- 2023
-
Ingår i: ACTA NEUROCHIRURGICA. - 0001-6268. ; 165
-
Tidskriftsartikel (refereegranskat)abstract
- Background We aim to investigate associations between preoperative radiological findings of lumbar foraminal stenosis with clinical outcomes after posterior microsurgical decompression in patients with predominantly central lumbar spinal stenosis (LSS). Methods The study was an additional analysis in the NORDSTEN Spinal Stenosis Trial. In total, 230 men and 207 women (mean age 66.8 ( SD 8.3)) were included. All patients underwent an MRI including T1- and T2-weighted sequences. Grade of foraminal stenosis was dichotomized into none to moderate (0-1) and severe (2-3) category using Lee's classification system. The Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ), and numeric rating scale (NRS) for back and leg pain were collected at baseline and at 2-year follow-up. Primary outcome was a reduction of 30% or more on the ODI score. Secondary outcomes included the mean improvement on the ODI, ZCQ, and NRS scores. We performed multivariable regression analyses with the radiological variates foraminal stenosis, Pfirrmann grade, Schizas score, dural sac cross-sectional area, and the possible plausible confounders: patients' gender, age, smoking status, and BMI. Results The cohort of 437 patients presented a high degree of degenerative changes at baseline. Of 414 patients with adequate imaging of potential foraminal stenosis, 402 were labeled in the none to moderate category and 12 in the severe category. Of the patients with none to moderate foraminal stenosis, 71% achieved at least 30% improvement in ODI. Among the patients with severe foraminal stenosis, 36% achieved at least 30% improvement in ODI. A significant association between severe foraminal stenosis and less chance of reaching the target of 30% improvement in the ODI score after surgery was detected: OR 0.22 (95% CI 0.06, 0.83), p=0.03. When investigating outcome as continuous variables, a similar association between severe foraminal stenosis and less improved ODI with a mean difference of 9.28 points (95%CI 0.47, 18.09; p=0.04) was found. Significant association between severe foraminal stenosis and less improved NRS pain in the lumbar region was also detected with a mean difference of 1.89 ( 95% CI 0.30, 3.49; p=0.02). No significant association was suggested between severe foraminal stenosis and ZCQ or NRS leg pain. Conclusion In patients operated with posterior microsurgical decompression for LSS, a preoperative severe lumbar foraminal stenosis was associated with higher proportion of patients with less than 30% improvement in ODI. Trial registration The study is registered at ClinicalTrials. gov (22.11.2013) under the identifier NCT02007083.
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| 36. |
- Aaen, J., et al.
(författare)
-
The association between preoperative MRI findings and clinical improvement in patients included in the NORDSTEN spinal stenosis trial
- 2022
-
Ingår i: European Spine Journal. - : Springer Science and Business Media LLC. - 0940-6719 .- 1432-0932. ; 31:10, s. 2777-2785
-
Tidskriftsartikel (refereegranskat)abstract
- Purpose To investigate potential associations between preoperative MRI findings and patient reported outcome measures (PROMs) after surgery for lumbar spinal stenosis (LSS). Methods The NORDSTEN trial included 437 patients. We investigated the association between preoperative MRI findings such as morphological grade of stenosis (Schizas grade), quantitative grade of stenosis (dural sac cross-sectional area), disc degeneration (Pfirrmann score), facet joint tropism and fatty infiltration of the multifidus muscle, and improvement in patient reported outcome measures (PROMs) 2 years after surgery. We dichotomized each radiological parameter into a moderate or severe category. PROMs i.e., Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ) and Numeric rating scale (NRS) for back and leg pain were collected before surgery and at 2 year follow-up. In the primary analysis, we investigated the association between MRI findings and ODI score (dichotomized to >= 30% improvement or not). In the secondary analysis, we investigated the association between MRI findings and the mean improvement on the ODI-, ZCQ- and NRS scores. We used multivariable regression models adjusted for patients' gender, age, smoking status and BMI. Results The primary analysis showed that severe disc degeneration (Pfirrmann score 4-5) was significantly associated with less chance of achieving a 30% improvement on the ODI score (OR 0.54, 95% CI 0.34, 0.88). In the secondary analysis, we detected no clinical relevant associations. Conclusion Severe disc degeneration preoperatively suggest lesser chance of achieving 30% improvement in ODI score after surgery for LSS. Other preoperative MRI findings were not associated with patient reported outcome.
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| 37. |
- Aagaard Nohr, Ellen, et al.
(författare)
-
Evidence-based midwifery
- 2022
-
Ingår i: Theories and perspectives for midwifery: a Nordic view. - Lund : Studentlitteratur. - 9789144143194 ; , s. 79-94
-
Bokkapitel (refereegranskat)abstract
- In this chapter, the history of evidence-based care and practice and their main principles will be presented, including a special focus on the field of obstetrics and midwifery. We will describe and discuss the main components of evidence-based midwifery and how they have been applied on important topics within maternal and newborn care. Finally, we will discuss the opportunities and challenges that midwives in the Nordic countries face when applying evidence-based care in a clinical setting that is dominated by large obstetric wards.
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| 38. |
- Aagaard, P., et al.
(författare)
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Early repolarization in ECG. Definition, prevalence and prognostic significance
- 2015
-
Ingår i: Läkartidningen. - 0023-7205. ; 112
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Tidskriftsartikel (refereegranskat)abstract
- Early repolarization defined as antero-lateral ST-segment elevation exists in 1-2 % of the general population and has been considered a benign ECG finding for decades. However, early repolarization, defined as infero-lateral J-waves, has in recent studies been associated with an increased - albeit low - risk of sudden and cardiovascular death. This ECG pattern is present in 3-13% of the general population. However, exercise training can induce all types of early repolarization, and the prevalence in the athletic population rises to 20-90%. There is large variability between sports (higher in endurance athletes) and also throughout the season (higher during times of peak fitness). In athletes, early repolarization, regardless of type, is considered benign. In asymptomatic non-athletes, the absolute risk is too low to use this ECG finding in clinical practice. In individuals with J-wave syndrome, on the other hand, ICD implantation should be strongly considered to prevent sudden cardiac death.
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| 39. |
- Aagaard, Philip, et al.
(författare)
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Early Repolarization in Middle-Age Runners-Cardiovascular Characteristics.
- 2014
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Ingår i: Medicine & Science in Sports & Exercise. - 0195-9131 .- 1530-0315. ; 46:7, s. 1285-1292
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: This study aimed to assess the prevalence and patterns of early repolarization (ER) in middle-age long-distance runners, its relation to cardiac structure and function, and its response to strenuous physical activity. Methods: Male first-time cross-country race participants >45 yr were assessed pre-and postrace by medical history and physical examination, 12-lead ECG, vectorcardiography, blood tests, and echocardiography. ER was defined either as ST elevation or J wave and categorized according to localization and morphology. Results: One hundred and fifty-one subjects (50 +/- 5 yr) were evaluated before the race, and 47 subjects were evaluated after the race. Altogether, 67 subjects (44%) had ER. Subjects with versus without ER had a lower resting HR (56 +/- 8 vs 69 +/- 9 bpm, P = 0.02), lower body mass index (24 +/- 2 vs 25 +/- 3 kg.m(-2), P < 0.001), higher training volume (3.0 +/- 2.6 vs 2.1 +/- 2.7 h.wk(-1), P = 0.03), and faster 30-km running times (194 +/- 28 vs 208 +/- 31 min, P = 0.01). Vectorcardiography parameters in subjects with ER showed more repolarization heterogeneity: vector gradient (QRS-T-area) (120 +/- 25 vs 92 +/- 29 mu Vs, P < 0.001), T-area (105 +/- 18 vs 73 +/- 23 mu Vs, P < 0.001), and T-amplitude (0.63 +/- 0.13 vs 0.53 +/- 0.16 mm, P < 0.001); these parameters were inversely related to HR (r = -0.37 to -0.48, P < 0.001). ER disappeared in 15 (75%) of 20 subjects after the race. Conclusions: ER is a common finding in middle-age male runners. This ECG pattern, regardless of morphology and localization, is associated with normal cardiac examinations including noninvasive electrophysiology, features of better physical conditioning, and disappears after strenuous exercise in most cases. These findings support that ER should be regarded as a common and training-related finding also in middle-age physically active men.
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| 40. |
- Aagaard, P., et al.
(författare)
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Heart Rate and Its Variability in Response to Running-Associations with Troponin
- 2014
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Ingår i: Medicine and Science in Sports and Exercise. - : Ovid Technologies (Wolters Kluwer Health). - 0195-9131. ; 46:8, s. 1624-1630
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The objective of this study is to investigate the time course of autonomic tone changes after a first-time endurance running race participation and associations with postexertional high-sensitivity troponin (hsTnT) levels in middle-aged males. Methods: Male (n = 42) first-time long-distance running race (Lidingoloppet 30 km) participants >= 45 yr (50.5 +/- 5) were examined. HR and HR variability (HRV) in the time domain (SDANN) was measured continuously from 2 d before to 4 d after the race using a wireless cardiovascular monitor that also recorded arrhythmia episodes. In addition, subjects were assessed pre- and postrace by medical history and physical examination, 12-lead ECG, blood tests including hsTnT, and echocardiography. Results: Compared with corresponding prerace values, nighttime (2: 00-4: 00 a.m.) HR was significantly elevated (63.6 +/- 9.4 vs 53.9 +/- 8.3 bpm, P < 0.001) on the first night postrace, whereas HRV remained reduced for a median of 64 h (interquartile range, 51-102 h). A prolonged HR recovery period (r = 0.48, P = 0.005) and a larger reduction in postrace HRV (r = -0.49, P = 0.003) correlated with higher postrace hsTnT levels. The association between reduced HRV and higher hsTnT remained significant after multivariate analysis (A = -0.48, P = 0.01). No sustained ventricular arrhythmias were recorded, but atrial fibrillation occurred in two subjects. Conclusion: Endurance running race participation caused a prolonged alteration of autonomic tone. More marked and prolonged changes were associated with higher levels of hsTnT, suggesting that the magnitude of troponin increase after strenuous exercise may reflect the magnitude of exercise-induced cardiovascular stress.
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| 41. |
- Aagaard, P, et al.
(författare)
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Preparticipation Evaluation of Novice, Middle-Age Long-Distance Runners.
- 2013
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Ingår i: Medicine and science in sports and exercise. - 0195-9131 .- 1530-0315. ; 45:1
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Tidskriftsartikel (refereegranskat)abstract
- Abstract PURPOSE: To assess the cardiovascular health and risk profile in middle-aged males making an entry to participate for their first time in a long-distance race. METHODS: Male first-time participants ≥45 years in the world's largest cross-country running race, the Lidingöloppet, were evaluated with a medical history and physical exam, European risk-SCORE, 12-lead ECG, echocardiography and blood tests. Further diagnostic work-up was performed when clinically indicated. RESULTS: Of 265 eligible runners, 153 (58%, age 51±5 y) completed the study. While the 10-year fatal cardiovascular event risk was low (SCORE: 1% (IQR: 0 - 1%)), mild abnormalities were common, e.g. elevated blood-pressure (19%), left ventricular hypertrophy (6%), elevated LDL cholesterol (5%). ECG changes compatible with "athlete's heart" were present in 82%, e.g. sinus bradycardia (61%) and/or early repolarization (32%). ECG changes considered training-unrelated were found in 24%, e.g. prolonged QTc: 13%; left axis deviation: 5.3%; left atrial enlargement: 4%). In 14 runners (9%) additional diagnostic work-up was clinically motivated, and 4 (2%) were ultimately discouraged from vigorous exercise due to QTc intervals >500 ms (n=2), symptomatic atrioventricular block (n=1), and a cardiac tumor (n=1). The physician exam and the ECG identified 12 of the 14 subjects requiring further evaluation. CONCLUSIONS: Cardiovascular evaluation of middle-aged men, including a physician exam and a 12-lead ECG, appears useful to identify individuals requiring further testing prior to vigorous exercise. The additional yield of routine echocardiography was small.
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| 42. |
- Aagaard, Philip, et al.
(författare)
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Tidig repolarisation på EKG - Definitioner, prevalens och prognostisk betydelse.
- 2015
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Ingår i: Läkartidningen. - 1652-7518. ; 112
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Tidskriftsartikel (refereegranskat)abstract
- Early repolarization defined as antero-lateral ST-segment elevation exists in 1-2 % of the general population and has been considered a benign ECG finding for decades. However, early repolarization, defined as infero-lateral J-waves, has in recent studies been associated with an increased - albeit low - risk of sudden and cardiovascular death. This ECG pattern is present in 3-13% of the general population. However, exercise training can induce all types of early repolarization, and the prevalence in the athletic population rises to 20-90%. There is large variability between sports (higher in endurance athletes) and also throughout the season (higher during times of peak fitness). In athletes, early repolarization, regardless of type, is considered benign. In asymptomatic non-athletes, the absolute risk is too low to use this ECG finding in clinical practice. In individuals with J-wave syndrome, on the other hand, ICD implantation should be strongly considered to prevent sudden cardiac death.
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| 43. |
- Aagerup, Ulf, 1969, et al.
(författare)
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Green consumer behavior: Being good or seeming good?
- 2016
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Ingår i: Journal of Product & Brand Management. - Bingley : Emerald Group Publishing Limited. - 1061-0421. ; 25:3, s. 274-284
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Tidskriftsartikel (refereegranskat)abstract
- Purpose This paper aims to expand the emerging field of symbolic green consumer behavior (GCB) by investigating the impact of anticipated conspicuousness of the consumption situation on consumers’ choice of organic products. In addition, the paper also explores whether self-monitoring ability and attention to social comparison information (ATSCI) influence GCB in situations of anticipated high conspicuousness. Design/methodology/approach Two experiments test the study’s hypotheses. Findings The results of both experiments show that the anticipation of conspicuousness has a significant effect on GCB. Moreover, in Experiment 2, this effect is moderated by consumers’ level of ATSCI but not by their self-monitoring ability. Research limitations/implications Because ATSCI significantly interacts with green consumption because of the anticipation of a conspicuous setting, although self-monitoring ability does not, we conclude that social identification is an important determinant of green consumption. Practical implications Marketers who focus on building green brands could consider designing conspicuous consumption situations to increase GCB. Social implications Policymakers could enact change by making the environmental unfriendliness of non-eco-friendly products visible to the public and thus increase the potential for GCB. Originality/value The results validate the emerging understanding that green products are consumed for self-enhancement, but also expand the literature by highlighting that a key motivating factor of GCB is the desire to fit in.
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| 44. |
- Aagerup, Ulf, 1969-
(författare)
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It’s Not What You Sell : It’s Whom You Sell it To: How the Customer’s Character Shapes Brands and What Companies Do About it
- 2015
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In this dissertation I investigate the effects of user and usage imagery on brands and how businesses employ user imagery to build brands. Over four articles I present results that suggest that user imagery affects brand personality and that companies under certain conditions adapt their behavior to optimize this effect. Although both mass market fashion and nightclubs are susceptible to the influence of user imagery, out of the two only nightclubs actively reject customers to improve its effect on brand perception. I relate these practices to the practical and financial feasibility of rejecting customers, the character of nightclubs’ brands, and to their inability to differentiate their brands through any other brand personality influencer besides user imagery. In this dissertation, I also discuss the ethical ramifications of user imagery optimization through customer rejection. In one study, the role of conspicuous usage imagery on socially desirable consumer behavior is investigated. It is concluded that conspicuousness increases consumers' propensity to choose environmentally friendly products, and that this tendency is especially pronounced for individuals that are high in attention to social comparison information. The conclusion is that consumers use green products to self-enhance for the purpose of fitting in with the group rather than to stand out from it.
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| 45. |
- Aagerup, Ulf, 1969, et al.
(författare)
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Self-enhancing green consumer behavior
- 2015
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Ingår i: The 10th annual Global Brand Conference, Turku, Finland, April 27-29.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- In the last few decades, the topic of environmental sustainability has received much attention within the marketing literature (Powell, 2011, Leonidou et al., 2013). As our world faces many environmental challenges, both large and small, the thought that part of the solution to these problems is in the consumption based arena has become more popular. To steer toward a more environmentally sustainable consumption is thus seen as desirable for many actors in society. However, while the concepts of green, sustainable, or environmental marketing have existed for several decades, the actual results of these initiatives are discouraging from both research and sustainability perspectives (Crane, 2000). There is a vast " attitude - behavior gap" (Moraes et al., 2 012, Carrington et al., 2010, Carrington et al., 2014) which means that although consumers profess to be positively disposed towards organic products, they do not act accordingly. Traditionally, research in this field has focused on how products’ functiona l benefits and consumers’ values and norms affect green consumer behavior (Salazar et al., 2013) . There is however an emerging understanding that consumers may seek more than functional value from their environmentally friendly brands, value like e.g. stat us (Griskevicius et al., 2010) and identity (Sexton and Sexton, 2011). Thus, for green products to be successful it may not be sufficient to only to be good; they must also make their user seem good. While building on the symbolic/expressive meaning of consumption is a commonly accepted idea within brand building (e.g. Park et al., 1986, Aaker, 1997, Fang et al., 2012) , it has received limited attention within the green consumer behavior domain. We propose that from the symbolic consumption perspective, environmentally friendly products that are consumed conspicuously should represent greater value than those that are consumed inconspicuously. Against this background, the purpose of this paper is to investigate if consumers choose environmentally friendly options to a greater extent if the consumption setting is public rather than private consumption situations.
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| 46. |
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| 47. |
- Aakre, K. M., et al.
(författare)
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Analytical Considerations in Deriving 99th Percentile Upper Reference Limits for High-Sensitivity Cardiac Troponin Assays: Educational Recommendations from the IFCC Committee on Clinical Application of Cardiac Bio-Markers
- 2022
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Ingår i: Clinical chemistry. - : Oxford University Press (OUP). - 0009-9147 .- 1530-8561. ; 68:8
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Tidskriftsartikel (refereegranskat)abstract
- The International Federation of Clinical Chemistry Committee on Clinical Application of Cardiac Bio-Markers provides evidence-based educational documents to facilitate uniform interpretation and utilization of cardiac biomarkers in clinical laboratories and practice. The committee's goals are to improve the understanding of certain key analytical and clinical aspects of cardiac biomarkers and how these may interplay in clinical practice. Measurement of high-sensitivity cardiac troponin (hs-cTn) assays is a cornerstone in the clinical evaluation of patients with symptoms and/or signs of acute cardiac ischemia. To define myocardial infarction, the Universal Definition of Myocardial Infarction requires patients who manifest with features suggestive of acute myocardial ischemia to have at least one cTn concentration above the sex-specific 99th percentile upper reference limit (URL) for hs-cTn assays and a dynamic pattern of cTn concentrations to fulfill the diagnostic criteria for MI. This special report provides an overview of how hs-cTn 99th percentile URLs should be established, including recommendations about prescreening and the number of individuals required in the reference cohort, how statistical analysis should be conducted, optimal preanalytical and analytical protocols, and analytical/biological interferences or confounds that can affect accurate determination of the 99th percentile URLs. This document also provides guidance and solutions to many of the issues posed.
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| 48. |
- Aakre, Kristin M, et al.
(författare)
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Lower Limits for Reporting High-Sensitivity Cardiac Troponin Assays and Impact of Analytical Performance on Patient Misclassification.
- 2024
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Ingår i: Clinical chemistry. - 0009-9147 .- 1530-8561. ; 70:3, s. 497-505
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Tidskriftsartikel (refereegranskat)abstract
- Cardiac troponin measurements are indispensable for the diagnosis of myocardial infarction and provide useful information for long-term risk prediction of cardiovascular disease. Accelerated diagnostic pathways prevent unnecessary hospital admission, but require reporting cardiac troponin concentrations at low concentrations that are sometimes below the limit of quantification. Whether analytical imprecision at these concentrations contributes to misclassification of patients is debated.The International Federation of Clinical Chemistry Committee on Clinical Application of Cardiac Bio-Markers (IFCC C-CB) provides evidence-based educational statements on analytical and clinical aspects of cardiac biomarkers. This mini-review discusses how the reporting of low concentrations of cardiac troponins impacts on whether or not assays are classified as high-sensitivity and how analytical performance at low concentrations influences the utility of troponins in accelerated diagnostic pathways. Practical suggestions are made for laboratories regarding analytical quality assessment of cardiac troponin results at low cutoffs, with a particular focus on accelerated diagnostic pathways. The review also discusses how future use of cardiac troponins for long-term prediction or management of cardiovascular disease may require improvements in analytical quality.Clinical guidelines recommend using cardiac troponin concentrations as low as the limit of detection of the assay to guide patient care. Laboratories, manufacturers, researchers, and external quality assessment providers should extend analytical performance monitoring of cardiac troponin assays to include the concentration ranges applicable in these pathways.
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| 49. |
- Aakvaag, Gunnar, et al.
(författare)
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Introduction
- 2012
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Ingår i: Introduction to Sociology. Scandinavian Sensibilities, Editors, Aakvag, Jacobsen and Johansson. - Harlow : Pearson. - 9780273727392
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 50. |
- Aalberg, Toril, et al.
(författare)
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Strategy and Game Framing
- 2017
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Ingår i: Comparing Political Journalism - (eds.) Claes de Vreese, Frank Esser & David Nicolas Hopmann. - New York : Routledge. - 9781138655867
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Bokkapitel (refereegranskat)
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