SwePub - sökning: id:"swepub:oai:lup.lub.lu.se:f...

Träfflista för sökning "id:"swepub:oai:lup.lub.lu.se:feda56ef-315b-4bc5-af89-874fdd5b27b8" "

Sökning: id:"swepub:oai:lup.lub.lu.se:feda56ef-315b-4bc5-af89-874fdd5b27b8"

Sortera/gruppera träfflistan

Sortering: Träffar per sida:

Numrering	Referens	Omslagsbild	Hitta
1.	Vassy, Jason L., et al. (författare) Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies 2011 Ingår i: Diabetes Research and Clinical Practice. - : Elsevier BV. - 1872-8227 .- 0168-8227. ; 93:2, s. 76-79 Tidskriftsartikel (refereegranskat)abstract Objective: Parental history of diabetes and specific gene variants are risk factors for type 2 diabetes, but the extent to which these factors are associated is unknown. Methods: We examined the association between parental history of diabetes and a type 2 diabetes genetic risk score (GRS) in two cohort studies from Finland (population-based PPP-Botnia study) and the US (family-based Framingham Offspring Study). Results: Mean (95% CI) GRS increased from 16.8 (16.8-16.9) to 16.9 (16.8-17.1) to 17.1 (16.8-17.4) among PPP-Botnia participants with 0, 1, and 2 parents with diabetes, respectively (p(trend) = 0.03). The trend was similar among Framingham Offspring but was not statistically significant (p = 0.07). The meta-analyzed p value for trend from the two studies was 0.005. Conclusions: The very modest associations reported above suggest that the increased risk of diabetes in offspring of parents with diabetes is largely the result of shared environmental/lifestyle factors and/or hitherto unknown genetic factors. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

Skapa referenser, mejla, bekava och länka

Träfflista för sökning "id:"swepub:oai:lup.lub.lu.se:feda56ef-315b-4bc5-af89-874fdd5b27b8" "