| 1. |
- Classon, Elisabet, et al.
(författare)
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A quick test of cognitive speed (AQT) : regression-based norms for cognitively healthy 80 to 94-year olds
- 2022
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Ingår i: Aging, Neuropsychology and Cognition. - : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. - 1382-5585 .- 1744-4128. ; 29:5, s. 820-839
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Tidskriftsartikel (refereegranskat)abstract
- Slowed processing speed is part of normal aging but also a symptom of many diseases, including dementia. A Quick Test of Cognitive Speed (AQT) consists of three conditions: color naming (AQT1), form naming (AQT2) and dual color-form naming (AQT3) and offers a user-friendly assessment of processing speed that is used internationally to identify cognitive impairment in elderly patients. Appropriate age-norms have however been lacking. This study provides regression-based norms derived from a Swedish sample of 158 cognitively healthy 80 to 94-year olds. The results show age effects in all three conditions, a non-linear education effect in AQT1, and age by gender interactions in AQT2 and AQT3: men performed worse with increasing age, but women remained on a par. However, irrespective of age and gender, AQT2 and AQT3 mean raw and predicted scores were slower than the hitherto recommended cutoff criteria for suspected cognitive impairment.
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| 2. |
- Fällman, Katarina, 1984-, et al.
(författare)
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Normative data for the oldest old: Trail Making Test A, Symbol Digit Modalities Test, Victoria Stroop Test and Parallel Serial Mental Operations
- 2020
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Ingår i: Aging, Neuropsychology and Cognition. - : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. - 1382-5585 .- 1744-4128. ; 27:4, s. 567-550
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Tidskriftsartikel (refereegranskat)abstract
- Normative data for evaluating cognitive function in the oldest old, aged 85 years and above, are currently sparse. The normative values used in clinical practice are often derived from younger old persons, from small sample sizes or from broad age spans (e.g. amp;gt;75 years) resulting in a risk of misjudgment in assessments of cognitive decline. This longitudinal study presents normative values for the Trail Making Test A (TMT-A), the Symbol Digit Modalities Test (SDMT), the Victoria Stroop Test (VST) and the Parallel Serial Mental Operations (PaSMO) from cognitively intact Swedes aged 85 years and above. 207 participants, born in 1922, were tested at 85, 90 (n = 68) and 93 (n = 35) years of age with a cognitive screening test battery. The participants were originally recruited for participation in the Elderly in Linkoping Screening Assessment. Normative values are presented as mean values and standard deviations, with and without adjustment for education. There were no clinically important differences between genders, but education had a significant effect on test results for the 85-year-olds. Age effects emerged in analyses of those participants who completed the entire study and were evident for TMT-A, SDMT, VST1 and PaSMO. When comparisons can be made, our results are in accordance with previous data for TMT-A, SDMT and VST, and we present new normative values for PaSMO.
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| 3. |
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| 4. |
- Samrani, George, et al.
(författare)
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Proactive interference in working memory is related to adult age and cognitive factors : cross-sectional and longitudinal evidence from the Betula study
- 2021
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Ingår i: Aging, Neuropsychology and Cognition. - : Routledge. - 1382-5585 .- 1744-4128. ; 28:1, s. 108-127
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Tidskriftsartikel (refereegranskat)abstract
- In working memory (WM), successful maintenance of information is affected by interference. Older adults may be especially susceptible to the effects of interference, which may cause age-related cognitive impairments. A relative score of IC was derived from cross-sectional (n = 869) and longitudinal (n = 443) data to investigate (1) if IC is reduced in normal aging, (2) if individual differences in IC related to individual performance in other cognitive domains, and (3) if 5-year change in IC is related to change in general cognition. Older age was associated with reduced IC, but no decline in IC occurred over 5 years. Also, the ability to control interference in WM was related to performance in episodic memory, verbal fluency, and block design. We also found that IC mediates the relationship between age and cognition, suggesting that age-related cognitive decline is linked to IC. Finally, we demonstrate that change in IC was related to decline in episodic memory.
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| 5. |
- Stenling, Andreas, 1982-, et al.
(författare)
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Physical activity and cognitive function: between-person and within-person associations and moderators
- 2021
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Ingår i: Aging, Neuropsychology and Cognition. - : Informa UK Limited. - 1382-5585 .- 1744-4128. ; 28:3, s. 392-417
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Tidskriftsartikel (refereegranskat)abstract
- In the present study, we decomposed between- and within-person effects and examined moderators of the longitudinal physical activity-cognition association. Participants (N = 1722) were drawn from the Betula study and we included four waves of data across 15 years. Bayesian multilevel modeling showed that self-reported physical activity did not predict changes in cognitive function. Physical activity positively predicted cognitive performance at baseline, and the relations were stronger for more active (compared to less active) older adults. Physical activity had a positive within-person effect on cognitive function. The within-person effect of physical activity on episodic memory recall was stronger for participants who on average engaged in less physical activity. The within-person effect on verbal fluency was stronger for participants with more education. Our results suggest that preserving cognitive functioning in old age might be more a matter of what you do in old age than reflecting what you did earlier in life.
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| 6. |
- Ziaei, Maryam, et al.
(författare)
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Neural correlates of affective empathy in aging : A multimodal imaging and multivariate approach
- 2022
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Ingår i: Aging, Neuropsychology and Cognition. - : Routledge. - 1382-5585 .- 1744-4128. ; 29:3, s. 577-598
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Tidskriftsartikel (refereegranskat)abstract
- Empathy is one such social-cognitive capacity that undergoes age-related change. C urrently, however, not well understood is the structural and functional neurocircuitry underlying age-related differences in empathy. This study aimed to delineate brain structural and functional networks that subserve affective empathic response in younger and older adults using a modified version of the Multifaceted Empathy Task to both positive and negative emotions. Combining multimodal neuroimaging with multivariate partial least square analysis resulted in two novel findings in older but not younger adults: (a) faster empathic responding to negative emotions was related to greater fractional anisotropy of the anterior cingulum and greater functional activity of the anterior cingulate network; (b) however, empathic responding to positive emotions was related to greater fractional anisotropy of the posterior cingulum and greater functional activity of the posterior cingulate network. Such differentiation of structural and functional networks might have critical implications for prosocial behavior and social connections among older adults.
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