| 1. |
- Andréasson, Emmeli, et al.
(författare)
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Uppdragsbrevet : en papperstiger
- 2013
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Ingår i: Balans. - : FAR. - 0346-8208.
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 2. |
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| 3. |
- Andreasson, Sven Arne, 1949
(författare)
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Netsim - Graphical Simulation of Distributed Algorithms and Protocols
- 2011
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Ingår i: proceedings of 2nd Abuual International Conference on Computer Science Education: Innovation and Technology. - 2251-2195. ; , s. 50-54
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Konferensbidrag (refereegranskat)abstract
- In this paper we describe the Netsim program which is used to graphically simulate distributed algorithms and protocols. The algorithms should be written in Java according to a given interface and can then be loaded into the Netsim program and be simulated using an appropriate network. Then the communication will be animated on the screen and the simulation can be controlled in different ways. After the simulation different data can be collected for further analysis.
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| 4. |
- Andréasson, Sven, et al.
(författare)
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Att förebygga sjukdom - en ledarskapsfråga
- 2010
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Ingår i: Läkartidningen. - : Sveriges läkarförbund. - 0023-7205 .- 1652-7518. ; 107:48, s. 3070-3071
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Chapman, Henry N, et al.
(författare)
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Femtosecond X-ray protein nanocrystallography.
- 2011
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 470:7332, s. 73-7
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Tidskriftsartikel (refereegranskat)abstract
- X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the necessary increase in X-ray dose to record data from crystals that are too small leads to extensive damage before a diffraction signal can be recorded. It is particularly challenging to obtain large, well-diffracting crystals of membrane proteins, for which fewer than 300 unique structures have been determined despite their importance in all living cells. Here we present a method for structure determination where single-crystal X-ray diffraction 'snapshots' are collected from a fully hydrated stream of nanocrystals using femtosecond pulses from a hard-X-ray free-electron laser, the Linac Coherent Light Source. We prove this concept with nanocrystals of photosystem I, one of the largest membrane protein complexes. More than 3,000,000 diffraction patterns were collected in this study, and a three-dimensional data set was assembled from individual photosystem I nanocrystals (∼200 nm to 2 μm in size). We mitigate the problem of radiation damage in crystallography by using pulses briefer than the timescale of most damage processes. This offers a new approach to structure determination of macromolecules that do not yield crystals of sufficient size for studies using conventional radiation sources or are particularly sensitive to radiation damage.
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| 6. |
- Cirillo, Marcello, 1978-, et al.
(författare)
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Integrated Motion Planning and Coordination for Industrial Vehicles
- 2014
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Ingår i: Proceedings of the 24th International Conference on Automated Planning and Scheduling. - : AAAI Press. - 9781577356608
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Konferensbidrag (refereegranskat)abstract
- A growing interest in the industrial sector for autonomous ground vehicles has prompted significant investment in fleet management systems. Such systems need to accommodate on-line externally imposed temporal and spatial requirements, and to adhere to them even in the presence of contingencies. Moreover, a fleet management system should ensure correctness, i.e., refuse to commit to requirements that cannot be satisfied. We present an approach to obtain sets of alternative execution patterns (called trajectory envelopes) which provide these guarantees. The approach relies on a constraint-based representation shared among multiple solvers, each of which progressively refines trajectory envelopes following a least commitment principle.
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| 7. |
- Crafoord, Sven, et al.
(författare)
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Experimental vitreous tamponade using polyalkylimide hydrogel
- 2011
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Ingår i: Graefe's Archives for Clinical and Experimental Ophthalmology. - : Springer Science and Business Media LLC. - 0721-832X .- 1435-702X. ; 249:8, s. 1167-74
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To evaluate polyalkylimide as a possible vitreous tamponading agent.METHODS: A 20-gauge pars plana vitrectomy and posterior vitreous detachment were performed in the right eye of six pigmented rabbits. Approximately 1 ml of viscoelastic gel, polyalkylimide (Bio-Alcamid) was thereafter injected into the vitreous space. Full-field ERG and intraocular pressure (IOP, Tonopen) was measured pre-and postoperatively at regular intervals up to 28 days. At day 6 or 28, the rabbits were sacrificed and the eyes were examined macroscopically, photographed, and prepared for histological examination with routine microscopy.RESULTS: The viscoelastic hydrogel was successfully injected, and remained translucent with preserved gel properties throughout the postoperative period. The postoperative IOP was unchanged compared to preoperative values. Five of six eyes displayed retinal edema or pigmentary changes centrally while the periphery appeared intact. ERG recordings showed a radical decrease in rod- and cone-derived B-wave amplitudes. Histological examination confirmed varying degrees of edema combined with neuronal cell death within the retinal layers in the central part of the fundus, while the peripheral part appeared intact.CONCLUSION: Polyalkylimide displays favourable physical properties when used as a vitreous tamponade. However, the hydrogel causes functional and morphological retinal damage when in direct contact with the inner retina. Possible pathological mechanisms include osmotic imbalance and direct toxic effects, and modification of biochemical properties is warranted before clinical use will be possible.
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| 8. |
- Mill, O., et al.
(författare)
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Analysis and development of hydro power research : synthesis within Swedish Hydro Power Centre
- 2010
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The market for hydropower re-investments in Sweden is approx 2.5 billion SEK/yr the coming decade. Large investments will also be carried out in Swedish tailing dams. This will result in challenging projects and need of experts. A crucial factor for a successful management of these challenges is the supply of engineers and researchers with hydro power and dam skills and knowledge. Swedish Hydro Power Centre (Svenskt vattenkraftcentrum, SVC) is a competence centre for university education and research environments within hydro power and mining dams. SVC comprises of two knowledge areas: Hydraulic Engineering and Hydro Turbines and Generators, respectively. SVC builds high-quality and long term sustainable knowledge at selected universities...
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| 9. |
- Pritchard, Christopher D., et al.
(författare)
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Evaluation of viscoelastic poly(ethylene glycol) sols as vitreous substitutes in an experimental vitrectomy model in rabbits
- 2011
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Ingår i: Acta Biomaterialia. - Oxon, United Kingdom : Elsevier. - 1742-7061 .- 1878-7568. ; 7:3, s. 936-943
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to employ an experimental protocol for in vivo evaluation of sols of 5 wt.% poly(ethylene glycol) (PEG) in phosphate-buffered saline as artificial vitreous substitutes. A 20 gauge pars plana vitrectomy and posterior vitreous detachment were performed in the right eye of eight pigmented rabbits. Approximately 1 ml of the viscoelastic PEG sols was then injected into the vitreous space of six eyes. PEG with an average molecular weight of 300,000 and 400,000 g mol(-1) was used in two and four eyes, respectively. Two eyes received balanced salt solution and served as controls. Full-field electroretinography was carried out and intra-ocular pressure (IOP, palpation) measured pre- and post-operatively at regular intervals up to 41 days. The rabbits were killed and the eyes examined by retinal photography, gross macroscopic examination and histology. The viscoelastic sols were successfully injected and remained translucent throughout the post-operative period, with some inferior formation of precipitates. None of the eyes displayed IOP elevation post-operatively, but in three of the PEG sol injected eyes transient hypotony was noted. One eye sustained retinal detachment during surgery and another two in the post-operative period. ERG recordings confirmed preservation of retinal function in three out of four eyes injected with 400,000 g mol(-1) PEG. Histological examination revealed up-regulation of glial acidic fibrillary protein in Müller cells in PEG sol injected eyes, but normal overall morphology in eyes with attached retinas. The viscosity of the sol was not retained throughout the post-operative period, indicating the demand for polymer cross-linking to increase residence time. The results provide promising preliminary results on the use of PEG hydrogels as a vitreous substitute.
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| 10. |
- Rath, Asawari D., et al.
(författare)
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Explosion dynamics of sucrose nanospheres monitored by time of flight spectrometry and coherent diffractive imaging at the split-and-delay beam line of the FLASH soft X-ray laser
- 2014
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Ingår i: Optics Express. - 1094-4087. ; 22:23, s. 28914-28925
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Tidskriftsartikel (refereegranskat)abstract
- We use a Mach-Zehnder type autocorrelator to split and delay XUV pulses from the FLASH soft X-ray laser for triggering and subsequently probing the explosion of aerosolised sugar balls. FLASH was running at 182 eV photon energy with pulses of 70 fs duration. The delay between the pump-probe pulses was varied between zero and 5 ps, and the pulses were focused to reach peak intensities above 1016 W/cm2 with an off-axis parabola. The direct pulse triggered the explosion of single aerosolised sucrose nano-particles, while the delayed pulse probed the exploding structure. The ejected ions were measured by ion time of flight spectrometry, and the particle sizes were measured by coherent diffractive imaging. The results show that sucrose particles of 560-1000 nm diameter retain their size for about 500 fs following the first exposure. Significant sample expansion happens between 500 fs and 1 ps. We present simulations to support these observations.
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