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Träfflista för sökning "WFRF:(Frisk T) srt2:(2010-2014)"

Sökning: WFRF:(Frisk T) > (2010-2014)

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1.
  • Meech, K. J., et al. (författare)
  • EPOXI: Comet 103P/Hartley 2 Observations from a Worldwide Campaign
  • 2011
  • Ingår i: Astrophysical Journal Letters. - London : IOP. - 2041-8213 .- 2041-8205. ; 734:L1, s. 1-9
  • Tidskriftsartikel (refereegranskat)abstract
    • Earth- and space-based observations provide synergistic information for space mission encounters by providing data over longer timescales, at different wavelengths and using techniques that are impossible with an in situ flyby. We report here such observations in support of the EPOXI spacecraft flyby of comet 103P/Hartley 2. The nucleus is small and dark, and exhibited a very rapidly changing rotation period. Prior to the onset of activity, the period was ~16.4?hr. Starting in 2010 August the period changed from 16.6?hr to near 19?hr in December. With respect to dust composition, most volatiles and carbon and nitrogen isotope ratios, the comet is similar to other Jupiter-family comets. What is unusual is the dominance of CO 2 -driven activity near perihelion, which likely persists out to aphelion. Near perihelion the comet nucleus was surrounded by a large halo of water-ice grains that contributed significantly to the total water production.
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  • Kasai, Y., et al. (författare)
  • Overview of the Martian atmospheric submillimetre sounder FIRE
  • 2012
  • Ingår i: Planetary and Space Science. - : Elsevier BV. - 0032-0633 .- 1873-5088. ; 63-64:SI, s. 62-82
  • Tidskriftsartikel (refereegranskat)abstract
    • We propose a submillimetre-wave atmospheric emission sounding instrument, called Far-InfraRed Experiment (FIRE), for the Japanese Martian exploration programme "Mars Exploration with Lander-Orbiter Synergy" (MELOS). The scientific target of FIRE/MELOS is to understand the dust suspended meteorology of the Mars. FIRE will provide key meteorological parameters, such as atmospheric temperature profiles for outside and inside dust storms, the abundance profile of the atmospheric compositions and their isotopes, and wind velocity profiles. FIRE will also provide the local time dependency of these parameters. The observational sensitivity of FIRE/MELOS is discussed in this paper. FIRE will explore the meteorological system of the Martian atmosphere including the interaction between its surface and atmosphere.
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  • Campbell-Thompson, M. L., et al. (författare)
  • The diagnosis of insulitis in human type 1 diabetes
  • 2013
  • Ingår i: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 56:11, s. 2541-2543
  • Tidskriftsartikel (refereegranskat)
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7.
  • Cavalie, T., et al. (författare)
  • Odin space telescope monitoring of water vapor in the stratosphere of Jupiter
  • 2012
  • Ingår i: Planetary and Space Science. - : Elsevier BV. - 0032-0633 .- 1873-5088. ; 61:1, s. 3-14
  • Tidskriftsartikel (refereegranskat)abstract
    • The Odin space telescope has monitored the H2O (1(10)-1(01)) line in Jupiter's stratosphere over the 2003-2009 period. When comparing these data with previous spectra obtained with SWAS and Odin over the 1999-2002 period, we see no significant variations in the line-to-continuum ratio of the H2O line over the whole period. We have however tentatively identified a decrease by similar to 15% of the line-to-continuum ratio between 2002 and 2007-2009, indicating that there was less H2O in the stratosphere of Jupiter in 2007-2009 than anticipated. We have tested the IDP (interplanetary dust particles) and SL9 (Shoemaker-Levy 9) 1D time-dependent models presented in Cavalie et al. [2008, Observation of water vapor in the stratosphere 613 of Jupiter with the Odin space telescope. Planetary and Space Science 56,1573-1584]. We present a series of scenarios that lead to satisfactory fits of the whole data set (1999-2002 and 2003-2009 periods) based on IDP and SL9 models. The evolution of Jupiter's stratospheric H2O that we have tentatively observed has however to be confirmed by Herschel/HIFI observations. If the decrease of the line-to-continuum ratio is confirmed by future observations, it would be a direct evidence that Jupiter's H2O comes from SW. In addition, this study shows that new constraints on Jupiter's eddy diffusion coefficient profile could be obtained (in the pressure ranges that are probed) from the monitoring of SW species in its stratosphere.
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8.
  • Chiang, S. C. C., et al. (författare)
  • Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production
  • 2013
  • Ingår i: Blood. - : American Society of Hematology. - 0006-4971 .- 1528-0020. ; 121:8, s. 1345-1356
  • Tidskriftsartikel (refereegranskat)abstract
    • Cytotoxic lymphocytes, encompassing cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, kill pathogen-infected, neoplastic, or certain hematopoietic cells through the release of perforin-containing lytic granules. In the present study, we first performed probability-state modeling of differentiation and lytic granule markers on CD8(+) T cells to enable the comparison of bona fide CTLs with NK cells. Analysis identified CD57(bright) expression as a reliable phenotype of granule marker-containing CTLs. We then compared CD3(+)CD8(+)CD57(bright) CTLs with NK cells. Healthy adult peripheral blood CD3(+)CD8(+)CD57(bright) CTLs expressed more granzyme B but less perforin than CD3(-)CD56(dim) NK cells. On stimulation, such CTLs degranulated more readily than other T-cell subsets, but had a propensity to degranulate that was similar to NK cells. Remarkably, the CTLs produced cytokines more rapidly and with greater frequency than NK cells. In patients with biallelic mutations in UNC13D, STX11, or STXBP2 associated with familial hemophagocytic lymphohistiocytosis, CTL and NK cell degranulation were similarly impaired. Therefore, cytotoxic lymphocyte subsets have similar requirements for Munc13-4, syntaxin-11, and Munc18-2 in lytic granule exocytosis. The present results provide a detailed comparison of human CD3(+)CD8(+)CD57(bright) CTLs and NK cells and suggest that analysis of CD57(bright) CTL function may prove useful in the diagnosis of primary immunodeficiencies including familial hemophagocytic lymphohistiocytosis.
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9.
  • Fan, B. X., et al. (författare)
  • Breakdown of the Cross-Kerr Scheme for Photon Counting
  • 2013
  • Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 110:5
  • Tidskriftsartikel (refereegranskat)abstract
    • We show, in the context of single-photon detection, that an atomic three-level model for a transmon in a transmission line does not support the predictions of the nonlinear polarizability model known as the cross-Kerr effect. We show that the induced displacement of a probe in the presence or absence of a single photon in the signal field, cannot be resolved above the quantum noise in the probe. This strongly suggests that cross-Kerr media are not suitable for photon counting or related single-photon applications. Our results are presented in the context of a transmon in a one-dimensional microwave waveguide, but the conclusions also apply to optical systems.
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