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- Wänman, Johan, et al.
(författare)
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Predictive Value of the Spinal Instability Neoplastic Score for Survival and Ambulatory Function After Surgery for Metastatic Spinal Cord Compression in 110 Patients with Prostate Cancer
- 2021
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Ingår i: Spine. - : Wolters Kluwer. - 0362-2436 .- 1528-1159. ; 46:8, s. 550-558
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Tidskriftsartikel (refereegranskat)abstract
- STUDY DESIGN: We retrospectively analyzed Spinal Instability Neoplastic Score (SINS) in 110 patients with prostate cancer operated for metastatic spinal cord compression (MSCC). OBJECTIVE: We aimed to investigate the association between SINS and clinical outcomes after surgery for MSCC in patients with prostate cancer. SUMMARY OF BACKGROUND DATA: The SINS is a useful tool for assessing tumor-related spinal instability, but its prognostic value regarding survival and neurological outcome is still controversial. METHODS: We analyzed 110 consecutive patients with prostate cancer who underwent surgery for MSCC. The patients were categorized according to their SINS. Patients with castration-resistant prostate cancer (CRPC, n = 84) and those with hormone-naïve disease (n = 26) were analyzed separately. RESULTS: In total, 106 of 110 patients met the SINS criteria for potential instability or instability (scores 7-18). The median SINS was 10 (range 6-15) for patients with CRPC and 9 (7-16) for hormone-naïve patients. In the CRPC group, the SINS was classified as stable (score 0-6) in 4 patients, as potentially unstable (score 7-12) in 70 patients, and as unstable (score 13-18) in 10 patients. In the hormone-naïve group, 22 patients met the SINS criteria for potential instability and 4 patients for instability. There was no statistically significant difference in the overall risk for death between the SINS potentially unstable and unstable categories (adjusted hazard ratio 1.3, P = 0.4), or in the risk of loss of ambulation 1 month after surgery (adjusted odds ratio 1.4, P = 0.6). CONCLUSION: The SINS is helpful in assessing spinal instability when selecting patients for surgery, but it does not predict survival or neurological outcomes. Patients with a potential spinal instability benefit equally from surgery for MSCC as do patients with spinal instability.Level of Evidence: 3.
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- Blanton, Michael R., et al.
(författare)
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Sloan Digital Sky Survey IV : Mapping the Milky Way, Nearby Galaxies, and the Distant Universe
- 2017
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Ingår i: Astronomical Journal. - : IOP Publishing Ltd. - 0004-6256 .- 1538-3881. ; 154:1
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Tidskriftsartikel (refereegranskat)abstract
- We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and. high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially resolved spectroscopy for thousands of nearby galaxies (median z similar to 0.03). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between z similar to 0.6 and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGNs. and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5 m Sloan Foundation Telescope at the. Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5 m du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in 2016 July.
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- Grabowski, Radoslaw
(författare)
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Burnt grain and crop cleaning residues: An archaeobotanical contribution to the understanding of 3rd–6th century ad longhouses in jutland and funen (Denmark)
- 2020
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Ingår i: Interdisciplinaria Archaeologica. - : Archeologicke Centrum Olomouc. - 1804-848X .- 2336-1220. ; 11:1, s. 47-62
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Tidskriftsartikel (refereegranskat)abstract
- This paper uses the composition and spatial distribution of carbonised archaeobotanical material from postholes to identify and delineate agrarian and household activities within settlements. The paper presents the analyses of seven houses/farmsteads dating to the 3rd–6th century AD, which were excavated on four separate sites: Flensted, Skovby Nygård and Gedved Vest in east-central Jutland, and Odensevej on the island of Funen. To infer settlement activities from the distributions of carbonised plant macro remains, the paper defines the various stages of plant processing and carbonisation circumstances. It also discusses assumptions about plant processing sequences and the formation of charred plant assemblages that were made during the analysis. The results show that the distribution of charred plant macro-remains can assist in the identification and delineation of spaces with different functions. The presented cases identify the locations of dwelling spaces, spaces where processed crops were stored and/or used, and spaces where fine sieving of grain was performed. The results also show a similarity between the analysed houses, which suggests the existence of a regional tradition of ordering household space. These patterns also confirm assumptions about mid-1st millennium houses previously made on the basis of other archaeological evidence.
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