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Träfflista för sökning "WFRF:(Harrison Peter) srt2:(2005-2009)"

Sökning: WFRF:(Harrison Peter) > (2005-2009)

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1.
  • Harrison, Dick, et al. (författare)
  • Medeltida sjukvård och medicin
  • 2008
  • Ingår i: Kronobäck - mötesplats då som nu. - 9789185926657 ; , s. 18-18
  • Bokkapitel (populärvet., debatt m.m.)
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2.
  • Harrison, Stephan, et al. (författare)
  • Glaciar Leon, Chilean Patagonia: late-Holocene chronology and geomorphology
  • 2008
  • Ingår i: Holocene. - : SAGE Publications. - 0959-6836. ; 18:4, s. 643-652
  • Tidskriftsartikel (refereegranskat)abstract
    • Glaciar Leon is a temperate, grounded outlet of the eastern North Patagonian Icefield (NPI). It terminates at an active calving margin in Lago Leones, a 10 km long proglacial lake. We take a multidisciplinary approach to its description and use ASTER imagery and clast sedimentology to describe the geomorphology of the glacier and its associated moraines. We date periods of glacier retreat over the last 2500 years using a combination of lichenometric, dendrochronological, cosmogenic and optically stimulated luminescence techniques and show that the glacier receded from a large terminal moraine complex some 2500 years ago and underwent further significant recession from nineteenth-century moraine limits. The moraine dates indicate varying retreat rates, in conjunction with significant downwasting. The bathymetry of Lago Leones is characterized by distinct ridges interpreted as moraine ridges that dissect the lake into several basins, with water depths reaching 360 m. The fluctuations of Glaciar Leon appear to have been controlled by the interplay between climatic forcing and calving dynamics.
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3.
  • Hasle, Henrik, et al. (författare)
  • Monosomy 7 and deletion 7q in children and adolescents with acute myeloid leukemia : an international retrospective study.
  • 2007
  • Ingår i: Blood. - 0006-4971. ; 109:11, s. 4641-7
  • Tidskriftsartikel (refereegranskat)abstract
    • Monosomy 7 (-7) and deletion 7q \del(7q)] are rare in childhood acute myeloid leukemia (AML). We retrospectively collected data on 258 children with AML or refractory anemia with excess blasts in transformation (RAEB-T) and -7 or del(7q) with or without other cytogenetic aberrations \+/- other]. Karyotypes included -7 (n = 90), -7 other (n = 82), del(7q) (n = 21), and del(7q) other (n = 65). Complete remission (CR) was achieved in fewer patients with -7 +/- other compared with del(7q) +/- other (61% versus 89%, P < .001). Overall, the 5-year survival rate was 39% (SE, 3%). Survival was superior in del(7q) +/- other compared with -7 +/- other (51% versus 30%, P < .01). Cytogenetic aberrations considered favorable in AML \t(8;21)(q22;q22), inv(16)(p13q22), t(15;17)(q22;q21), t(9;11)(p22;q23)] (n = 24) were strongly associated with del(7q) and a higher 5-year survival rate compared with del(7q) without favorable cytogenetics (75% versus 46%, P = .03). Patients with -7 and inv(3),-5/del(5q), or + 21 had a 5-year survival rate of 5%. Stem cell transplantation analyzed as a time-dependent variable had no impact on overall survival. However, patients not achieving CR had a 31% survival rate after stem cell transplantation. Childhood AML with chromosome 7 aberrations represents a heterogeneous group of disorders with additional cytogenetic aberrations having a major prognostic impact which should be reflected in future risk-group stratification.
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