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Träfflista för sökning "WFRF:(Nordgren Anders) srt2:(2010-2014)"

Sökning: WFRF:(Nordgren Anders) > (2010-2014)

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  • Ahlgren, Jennie, et al. (författare)
  • Consumers on the Internet : ethical and legal aspects of commercialization of personalized nutrition
  • 2013
  • Ingår i: Genes & Nutrition. - : Springer. - 1555-8932 .- 1865-3499. ; 8:4, s. 349-355
  • Forskningsöversikt (refereegranskat)abstract
    • Consumers often have a positive attitude to the option of receiving personalized nutrition advice based upon genetic testing, since the prospect of enhancing or maintaining one’s health can be perceived as empowering. Current direct-to-consumer services over the Internet, however, suffer from a questionable level of truthfulness and consumer protection, in addition to an imbalance between far-reaching promises and contrasting disclaimers. Psychological and behavioral studies indicate that consumer acceptance of a new technology is primarily explained by the end user’s rational and emotional interpretation as well as moral beliefs. Results from such studies indicate that personalized nutrition must create true value for the consumer. Also, the freedom to choose is crucial for consumer acceptance. From an ethical point of view, consumer protection is crucial, and caution must be exercised when putting nutrigenomic-based tests and advice services on the market. Current Internet offerings appear to reveal a need to further guaranty legal certainty by ensuring privacy, consumer protection and safety. Personalized nutrition services are on the borderline between nutrition and medicine. Current regulation of this area is incomplete and undergoing development. This situation entails the necessity for carefully assessing and developing existing rules that safeguard fundamental rights and data protection while taking into account the sensitivity of data, the risks posed by each step in their processing, and sufficient guarantees for consumers against potential misuse.
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4.
  • Gunnarsson, Stefan, et al. (författare)
  • Meat production, climate change and ethics
  • 2011
  • Ingår i: Proceedings of the XVth International Congress of theInternational Society for Animal Hygiene (vol.1). - Brno, Czech Republic : Tribun EU s.r.o.. - 9788026300083 ; , s. 209-211
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Humans contribute substantially to the emissions of carbon dioxide causing global warming, and meat producing livestock contributes to this. Estimates of the global greenhouse gas emissions from the livestock sector vary from 5% to 50%. Nevertheless, the emissions are in absolute terms substantial, and the issue needs to be mitigated. The present paper analyses and discusses various solutions for how to mitigate climate change to the extent it is caused by animal production. The ethical problem of mitigation of climate change, to the extent it is caused by animal production, is an extremely complex anddifficult issue. There are different views on the nature and scale of impact and different mitigation approaches, as well as different ethical aspects of the mitigation approaches.
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  • Laurell, Tobias, et al. (författare)
  • Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease.
  • 2014
  • Ingår i: Molecular Genetics & Genomic Medicine. - : Wiley. - 2324-9269. ; 2:5, s. 402-411
  • Tidskriftsartikel (refereegranskat)abstract
    • Nonsense mutations in FGF16 have recently been linked to X-linked recessive hand malformations with fusion between the fourth and the fifth metacarpals and hypoplasia of the fifth digit (MF4; MIM#309630). The purpose of this study was to perform careful clinical phenotyping and to define molecular mechanisms behind X-linked recessive MF4 in three unrelated families. We performed whole-exome sequencing, and identified three novel mutations in FGF16. The functional impact of FGF16 loss was further studied using morpholino-based suppression of fgf16 in zebrafish. In addition, clinical investigations revealed reduced penetrance and variable expressivity of the MF4 phenotype. Cardiac disorders, including myocardial infarction and atrial fibrillation followed the X-linked FGF16 mutated trait in one large family. Our findings establish that a mutation in exon 1, 2 or 3 of FGF16 results in X-linked recessive MF4 and expand the phenotypic spectrum of FGF16 mutations to include a possible correlation with heart disease.
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7.
  • Lerner, Henrik, et al. (författare)
  • Livestock’s “short shadow”? : Balancing mitigation of climate change against other values
  • 2011
  • Ingår i: Proceedings of the XVth International Congress of theInternational Society for Animal Hygiene (vol.1). - Brno, Czech Republic : Tribun EU s.r.o.. - 9788026300083 ; , s. 213-214
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Livestock has been said to cast a long shadow on climate change. However, environmental protection has also other aspects. This paper analyses one possible conflict between environmental goals in Sweden: to decrease the number of ruminants in order to minimise the impact on climate change and to maintain the number of ruminants in order to preserve biological diversity. Some Swedish stakeholders seem to argue that preserving biological diversity carries as much weight as mitigating climate change. This can be interpreted as if ruminants are considered to be good for the environment despite their impact on climate change, and thus shortening the long shadow. We point out, however, that only a fraction of ruminants are grazing pastures with high biodiversity. For most Swedish meat production, this argument is of minor importance for environmental sustainability.
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8.
  • Lerner, Henrik, 1975-, et al. (författare)
  • Stakeholders on Meat Production, Meat Consumption and Mitigation of Climate Change : Sweden as a Case
  • 2013
  • Ingår i: Journal of Agricultural and Environmental Ethics. - : Springer Science and Business Media LLC. - 1187-7863 .- 1573-322X. ; 26:3, s. 663-678
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper we analyse and discuss the views of Swedish stakeholders on how to mitigate climate change to the extent it is caused by meat production. The stakeholders include meat producer organisations, governmental agencies with direct influence on meat production, political parties as well as non-governmental organisations. Representatives of twelve organisations were interviewed. Several organisations argued against the mitigation option of reducing beef production despite the higher greenhouse gas intensity of beef compared to pork and chicken meat (according to life cycle analysis). Regarding feed production some organisations proposed use of the best available industrial fertilizers, others were against all use of such fertilizers. Several organizations suggested domestic production of more protein-rich fodder and use of manure for biogas production. Regarding meat consumption the focus was on throwing away less food as waste and on eating less meat but the best (most climate friendly) meat, which was considered to be Swedish meat in contrast to imported meat. There was agreement on many issues. Most disagreement was found regarding political steering. We find many of the stakeholders' mitigation proposals regarding meat production and consumption acceptable. However, we are to some extent critical to their defence of Swedish beef production. We also point out certain problems with the suggestion to reduce consumption of imported meat but not of domestically produced meat.
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9.
  • Lindström, Niclas (författare)
  • Förhållandet mellan praxis och teori inom etiken
  • 2012
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The main question of this thesis is if a practice is right because it is prescribed by an ethical theory, or if an ethical theory is right because it follows from certain practices? I propose the following definitions to illustrate the main alternatives: (1) if a practice is determined by an ethical theory and the ethical theory is not determined by practice, it is possible to speak of a top-down model of ethical thinking. (2) If a theory, conversely, is determined by a practice and the practice is not determined by theory, it can be described as a bottom-up model. (3) If a practice is used in order to determine an ethical theory, which in turn can be used to assess new practical situations in a constantly evolving process, it can be labelled an interaction model. (4) Finally, it is possible that certain practices are the basis of morality, and do not need to be systemized in any ethical theory. The focus of this study is on alternatives (2), (3) and (4) where practice is given due weight and is characterized by a rejection of a strictly theoretical approach to ethics. I address representatives from some of the most influential alternatives such as: (2) Albert R Jonsen & Stephen Toulmin (casuistry), (3) Jürgen Habermas (discourse ethics), Alasdair MacIntyre (virtue ethics), Jonathan Haidt (experimental ethics) and (4) John Dewey, Hilary Putnam and Richard Rorty (pragmatism). I also discuss how some prominent theologians, such as Stanley Hauerwas (Christian virtue ethics) and James Gustafson (theocentric ethics), deal with similar questions. The purpose of this study is therefore to identify various positions represented in the debate, and to examine which consequences they have for how decisions are made and justified within an ethical framework. I argue that the strength of models that include practical concerns in ethical thinking is that they can contribute to our understanding of why ideals, norms and values differ between various social spheres, and how they change over time. Instead of taking the traditional position, where a basic assumption about the nature of moral questions is crucial to identify a reliable approach, it is possible to assess which approaches give reliable results and use these to identify the factors relevant to answer moral questions. I identify two main alternatives: a paradigmatic and a discursive way of treating moral issues. They address various aspects of human life and action, which means that they do not exclude, but rather enrich each other in the context of an overall debate. It seems possible that both types of studies can provide reasons for performing an action or accepting a theory, which can then be revised and give rise to new positions. From such a perspective, neither the image of man and the world, nor our standards, ideals and values are necessarily static, but can be revised and reconsidered within the context of a changing social, cultural and historical context.
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10.
  • Modin, Anders, et al. (författare)
  • Indication of single-crystal PuO2 oxidation from O 1s x-ray absorption spectra
  • 2011
  • Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 83:7, s. 075113-
  • Tidskriftsartikel (refereegranskat)abstract
    • The electronic structure of single-crystal PuO2 is studied using O 1s x-ray absorption (XA) and x-ray emission. Interpretation of the experimental data is supported by extensive first-principles calculations on the basis of the density functional theory + U approach. The measured XA spectra show a significant difference in intensity for the first two peaks between different spots or areas on the single crystal. Our theoretical simulations show that the first peak, at similar to 531 eV, can be attributed to O 2p-Pu 5f hybridization, while the second peak, at similar to 533.4 eV, is due to hybridization of O 2p with Pu d states. The reasons for the observed differences in the O 1s XA spectra are explored by calculating a number of defect structures PuO2+x as well as by simulating the existence of Pu(V) sites. Our results indicate the presence of oxidation states higher than Pu(IV) in some areas of the single crystal. The findings also suggest that plutonium oxide with a Pu fraction in an oxidation state higher than Pu(IV) consists of inequivalent Pu sites with (PuO2)-O-(IV) and (PuO2)-O-(V) rather than representing a system where the Pu oxidation state is constantly fluctuating between Pu(IV) and Pu(V).
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