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1.	Jakobsson, J., et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Journal article (peer-reviewed)
2.	Abudu, YP, et al. (author) SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components 2021 In: The Journal of cell biology. - : Rockefeller University Press. - 1540-8140 .- 0021-9525. ; 220:8 Journal article (peer-reviewed)abstract Mitophagy is the degradation of surplus or damaged mitochondria by autophagy. In addition to programmed and stress-induced mitophagy, basal mitophagy processes exert organelle quality control. Here, we show that the sorting and assembly machinery (SAM) complex protein SAMM50 interacts directly with ATG8 family proteins and p62/SQSTM1 to act as a receptor for a basal mitophagy of components of the SAM and mitochondrial contact site and cristae organizing system (MICOS) complexes. SAMM50 regulates mitochondrial architecture by controlling formation and assembly of the MICOS complex decisive for normal cristae morphology and exerts quality control of MICOS components. To this end, SAMM50 recruits ATG8 family proteins through a canonical LIR motif and interacts with p62/SQSTM1 to mediate basal mitophagy of SAM and MICOS components. Upon metabolic switch to oxidative phosphorylation, SAMM50 and p62 cooperate to mediate efficient mitophagy.
3.	Klionsky, DJ, et al. (author) Autophagy in major human diseases 2021 In: The EMBO journal. - : EMBO. - 1460-2075 .- 0261-4189. ; 40:19, s. e108863- Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Tooze, SA (3); Johansen, T (3); Kumar, S (2); Madeo, F (2); Kroemer, G (2); Abudu, YP (2); show more...; Behrends, C (2); Lamark, T (2); Simon, HU (2); Martínez, J. (2); Cadwell, K (2); Jakobsson, J. (2); Galluzzi, L (2); Hansen, M (2); Simon, AK (2); Tavernarakis, N (2); Rubinsztein, DC (2); Pietrocola, F (2); Melendez, A (2); Ballabio, A (2); Juhasz, G (2); Boya, P (2); Cecconi, F (2); Bravo-San Pedro, JM (2); Eskelinen, EL (2); Negoita, F. (2); Sadoshima, J (2); Ktistakis, NT (2); Yue, ZY (2); Gewirtz, DA (2); Chu, CT (2); Baehrecke, EH (2); Munz, C (2); Codogno, P (2); Kraft, C (2); Deretic, V (2); Mizushima, N (2); Reggiori, F (2); Yoshimori, T (2); Jaattela, M (2); Yuan, JY (2); Fimia, GM (2); Green, DR (2); Dikic, I (2); Ryan, KM (2); Santambrogio, L (2); Zhong, Q (2); Pircs, K. (2); Choi, AMK (2); Choi, ME (2); show less...

University: Karolinska Institutet (3); Umeå University (1); Stockholm University (1); Linköping University (1); Lund University (1); Swedish University of Agricultural Sciences (1)

Language: English (3)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

Year: 2021 (3)Undo refine

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