| 1. |
- Anghinolfi, Francisco, et al.
(författare)
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DTMROC-S: Deep submicron version of the readout chip for the TRT detector in ATLAS
- 2002
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Ingår i: 8th Workshop On Electronics For LHC Experiments. ; , s. 95-99
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Konferensbidrag (refereegranskat)abstract
- A new version of the circuit for the readout of the ATLAS straw tube detector, TRT [1], has been developed in a deep-submicron process. The DTMROC-S is fabricated in a commercial 0.25μm CMOS IBM technology, with a library hardened by layout techniques [2]. Compared to the previous version of the chip [3] done in a 0.8μm radiation-hard CMOS and despite of the features added for improving the robustness and testability of the circuit, the deep-submicron technology results in a much smaller chip size that increases the production yield and lowers the power consumption.
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| 2. |
- Jeacocke, David, et al.
(författare)
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Combining quantitative and qualitative research to engage stakeholders in developing quality indicators in general practice.
- 2002
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Ingår i: Australian health review : a publication of the Australian Hospital Association. - 0156-5788. ; 25:4, s. 12-8
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Tidskriftsartikel (refereegranskat)abstract
- In 2000, the Newcastle Institute of Public Health (NIPH) undertook a project that aimed to review, identify and where necessary, develop a range of indicators of quality service provision in general practice. We describe the way in which quantitative and qualitative research methods (including a Delphi style survey) were combined to investigate consensus amongst stakeholders in defining quality indicators. Over 500 general practice stakeholders were consulted. They included general practitioners (GPs) and their representative groups, academics, policy makers, and consumers. Several important lessons were learnt from the process, including the importance of involving a broad representative group of stakeholders, informing workshop participants in advance, providing adequate response times for the Delphi surveys and using videoconferencing technologies.
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| 3. |
- Johansson, Richard, et al.
(författare)
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Carsim: A System to Convert Written Accident Reports into Animated 3D Scenes
- 2004
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Ingår i: Proceedings of the 2nd Joint SAIS/SSLS Workshop Artificial Intelligence and Learning Systems, AILS-04. ; , s. 76-86
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Konferensbidrag (refereegranskat)abstract
- This paper describes a system to create animated 3D scenes of car accidents from reports written in Swedish. The system has been developed using news reports of varying size and complexity. The text-to-scene conversion process consists of two stages. An information extraction module creates a tabular description of the accident and a visual simulator generates and animates the scene. We first describe the overall structure of the text-to-scene conversion and the template structure. We then explain the information extraction and visualization modules. We show snapshots of the car animation output and we conclude with the results we obtained.
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| 4. |
- Johansson, Richard, et al.
(författare)
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Carsim: A System to Visualize Written Road Accident Reports as Animated 3D Scenes
- 2004
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Ingår i: Proceedings of the 2nd Workshop on Text Meaning and Interpretation. ; , s. 57-64
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Konferensbidrag (refereegranskat)abstract
- This paper describes a system to create animated 3D scenes of car accidents from reports written in Swedish. The system has been developed using news reports of varying size and complexity. The text-to-scene conversion process consists of two stages. An information extraction module creates a structured representation of the accident and a visual simulator generates and animates the scene. We first describe the overall structure of the text-to-scene conversion and the structure of the representation. We then explain the information extraction and visualization modules. We show snapshots of the car animation output and we conclude with the results we obtained.
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| 5. |
- Johansson, Richard, et al.
(författare)
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Converting texts of road accidents into 3D scenes
- 2004
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Ingår i: ECAI 2004, Proceedings of the 16th European Conference on Artificial Intelligence. ; 110, s. 1035-1036
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Konferensbidrag (refereegranskat)abstract
- This paper describes a system to create animated 3D scenes of car accidents from reports written in Swedish. The system has been developed using news reports of varying size and complexity. The text-to-scene conversion process consists of two stages. An information extraction module creates a tabular description of the accident and a visual simulator generates and animates the scene.
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| 6. |
- Lewis, Cathryn M, et al.
(författare)
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Genome scan meta-analysis of schizophrenia and bipolar disorder, part II : Schizophrenia
- 2003
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Ingår i: American Journal of Human Genetics. - 0002-9297 .- 1537-6605. ; 73:1, s. 34-48
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Tidskriftsartikel (refereegranskat)abstract
- Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports of significant genetic linkage. To assess evidence for linkage across studies, rank-based genome scan meta-analysis (GSMA) was applied to data from 20 schizophrenia genome scans. Each marker for each scan was assigned to 1 of 120 30-cM bins, with the bins ranked by linkage scores (1 = most significant) and the ranks averaged across studies (R(avg)) and then weighted for sample size (N(sqrt)[affected casess]). A permutation test was used to compute the probability of observing, by chance, each bin's average rank (P(AvgRnk)) or of observing it for a bin with the same place (first, second, etc.) in the order of average ranks in each permutation (P(ord)). The GSMA produced significant genomewide evidence for linkage on chromosome 2q (PAvgRnk<.000417). Two aggregate criteria for linkage were also met (clusters of nominally significant P values that did not occur in 1,000 replicates of the entire data set with no linkage present): 12 consecutive bins with both P(AvgRnk) and P(ord)<.05, including regions of chromosomes 5q, 3p, 11q, 6p, 1q, 22q, 8p, 20q, and 14p, and 19 consecutive bins with P(ord)<.05, additionally including regions of chromosomes 16q, 18q, 10p, 15q, 6q, and 17q. There is greater consistency of linkage results across studies than has been previously recognized. The results suggest that some or all of these regions contain loci that increase susceptibility to schizophrenia in diverse populations.
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| 7. |
- Williams, Amanda M, et al.
(författare)
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Intestinal alpha beta T cells differentiate and rearrange antigen receptor genes in situ in the human infant.
- 2004
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Ingår i: Journal of immunology (Baltimore, Md. : 1950). - 0022-1767. ; 173:12, s. 7190-9
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Tidskriftsartikel (refereegranskat)abstract
- Intestinal Ag exposure during neonatal life influences appropriate adult immune responses. To define the mechanisms shaping the T cell repertoire during this period, we examined T cell differentiation and receptor diversity in the intestine of human infants. Developmental phenotypes of intraepithelial and lamina propria intestinal T cells from infants aged 1 day to 2 years were assessed ex vivo by flow cytometry and in situ by triple-fluorescent immunohistochemistry. Gene recombination-specific enzymes were assessed by PCR. TCR beta-chain V region gene diversity was determined by sequencing. Several different early lineage T cell populations were present neonatally: CD3(+)4(-)8(-) T cells were present at birth and numbers decreased during the neonatal period; CD3(+)4(+)8(+) T cells were present in low numbers throughout infancy; and CD3(+)4(+)8(-) or CD3(+)4(-)8(+) T cells increased with age. Very early lineage T cells, CD3(-)2(-)7(+) and CD3(-)2(+)7(+), were present neonatally, but were essentially absent at 1 year. Most lamina propria T cells differentiated rapidly after birth, but maturation of intraepithelial T cells took place over 1 year. Intestinal samples from infants less than 6 mo old contained transcripts of T early alpha and TdT, and 15 of 19 infant samples contained mRNA for RAG-1, some coexpressing RAG-2. TCR beta-chain repertoires were polyclonal in infants. Immature T cells, pre-T cells, and genes involved in T cell recombination were found in the intestine during infancy. T cell differentiation occurs within the neonatal human intestine, and the TCR repertoire of these developing immature T cells is likely to be influenced by luminal Ags. Thus, mucosal T cell responsiveness to environmental Ag is shaped in situ during early life.
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