| 1. |
- Weinstein, John N., et al.
(författare)
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The cancer genome atlas pan-cancer analysis project
- 2013
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:10, s. 1113-1120
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Forskningsöversikt (refereegranskat)abstract
- The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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| 2. |
- Al-Rawi, Ali, 1985, et al.
(författare)
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A new compact wideband MIMO antenna – the double-sided tapered self-grounded monopole array
- 2014
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Ingår i: IEEE Transactions on Antennas and Propagation. - 0018-926X .- 1558-2221. ; 62:6, s. 3365 - 3369
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Tidskriftsartikel (refereegranskat)abstract
- We present a new compact wideband multiple input multiple output (MIMO) antenna—the double-sided 4-port arm-tapered self-grounded monopole array, briefly referred to as the butterfly antenna, in the communication. The antenna is very compact with low correlation between ports and high diversity gain. The genetic algorithm optimization scheme has been employed in the design. Simulation results have been verified against measurements. The measured reflection coefficients at all ports are below -7 dB over 0.5–9 GHz and below -4.5 dB over 0.4–0.5 GHz and 9–15 GHz. The measured correlation coefficients are below 0.4 over 0.4–15 GHz and lower than 0.1 in most of the frequency band. This new MIMO antenna is developed as a transmit antenna in reverberation chambers, and we believe that it will find more applications in other systems, such as micro base station antennas in wireless communication systems.
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| 5. |
- Al Mouatamid, Faouzi, 1989, et al.
(författare)
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Towards Evaluation of Post Impact Braking Function in Driving Simulator
- 2013
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Ingår i: Proceedings of the IEEE International Conference on Systems, Man, and Cybernetics, Manchester, United Kingdom, Oct 13-16, 2013.. - 9780769551548 ; , s. 4549-4554
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Konferensbidrag (refereegranskat)abstract
- This paper presents a method to evaluate the vehicle Post Impact Braking function in driving simulator environment. This function is designed to apply automatic braking after an initial impact on the vehicle body. Four representative impact scenarios and three typical driving styles are investigated, assuming Anti-lock Brake System (ABS) is either functioned or malfunctioned. The performance of PIB is quantified by comparing certain post impact states when the function is enabled and disabled. The results show that PIB helps the drivers to lower the risk and severity of secondary collisions with respect to reduced displacements and road leaving speed; while it leads to higher risk for possible side collisions due to increased yaw angle; these influences seem to be more considerable when no ABS is available. Passive drivers are found to gain more benefits than Alert-Skilled drivers that it indicates full-braking can degrade the vehicle steerability and thus the lateral and yaw responses to some extent. © 2013 IEEE.
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| 6. |
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| 7. |
- Al-Rawi, Ali, 1985, et al.
(författare)
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The Double-sided 4-port Bow-tie Antenna: A New Compact Wideband MIMO Antenna
- 2013
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Ingår i: 7th European Conference on Antennas and Propagation, EuCAP 2013, Gothenburg, Sweden, 8-12 April 2013. - 2164-3342. - 9788890701832 ; , s. 3731-3735
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Konferensbidrag (refereegranskat)abstract
- We present a new compact ultra-wideband 4-port antenna for use in MIMO systems, such as in reverberation chambers for OTA measurements. The new antenna is based on the self-grounded bow-tie antenna with a very compact size. The design was done through an optimization by employing the genetic algorithm in order to obtain low reflection coefficient and mutual coupling between ports. The designed antenna has an embedded radiation efficiency higher than -0.35 dB, reflection coefficient below -7 dB, mutual coupling between ports below - 12.5 dB (in most frequencies below -20 dB), over a frequency range of 0.4–15 GHz.
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| 8. |
- Han, Guangye, et al.
(författare)
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Hydration of the oxygen-evolving complex of photosystem II probed in the dark-stable S1 state using proton NMR dispersion profiles
- 2014
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Ingår i: Physical Chemistry, Chemical Physics - PCCP. - : Royal Society of Chemistry. - 1463-9076 .- 1463-9084. ; :16, s. 11924-11935
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Tidskriftsartikel (refereegranskat)abstract
- The hydration of the oxygen-evolving complex (OEC) was characterized in the dark stable S1 state of photosystem II using water R1(ω) NMR dispersion (NMRD) profiles. The R1(ω) NMRD profiles were recorded over a frequency range from 0.01 MHz to 40 MHz for both intact and Mn-depleted photosystem II core complexes from Thermosynechococcus vulcanus (T. vulcanus). The intact-minus-(Mn)-depleted difference NMRD profiles show a characteristic dispersion from approximately 0.03 MHz to 1 MHz, which is interpreted on the basis of the Solomon-Bloembergen-Morgan (SBM) and the slow motion theories as being due to a paramagnetic enhanced relaxation (PRE) of water protons. Both theories are qualitatively consistent with the ST = 1, g = 4.9 paramagnetic state previously described for the S1 state of the OEC; however, an alternative explanation involving the loss of a separate class of long-lived internal waters due to the Mn-depletion procedure can presently not be ruled out. Using a point-dipole approximation the PRE-NMRD effect can be described as being caused by 1-2 water molecules that are located about 10 Å away from the spin center of the Mn4CaO5 cluster in the OEC. The application of the SBM theory to the dispersion observed for PSII in the S1 state is questionable, because the parameters extracted do not fulfil the presupposed perturbation criterion. In contrast, the slow motion theory gives a consistent picture indicating that the water molecules are in fast chemical exchange with the bulk (τw < 1 μs). The modulation of the zero-field splitting (ZFS) interaction suggests a (restricted) reorientation/structural equilibrium of the Mn4CaO5 cluster with a characteristic time constant of τZFS = 0.6-0.9 μs.
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| 9. |
- Huang, Yang, 1985-, et al.
(författare)
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The water R1(ω) NMRD profiles of a hydrated protein from molecular dynamics simulation
- 2013
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Ingår i: Physical Chemistry, Chemical Physics - PCCP. - : RSC Publishing. - 1463-9076 .- 1463-9084. ; 15:33, s. 14089-14097
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Tidskriftsartikel (refereegranskat)abstract
- The hydration of a protein, peroxiredoxin 5, is obtained from a molecular dynamics simulation and compared with the picture of hydration which is obtained by analysing the water proton R1 NMRD profiles using a generally accepted relaxation model [K. Venu, V.P. Denisov and B. Halle, J. Am. Chem. Soc. 119,3122(1997)]. The discrepancy between the hydration pictures derived from the water R1(ω 0)-NMRD profiles and MD is relevant in a discussion of the factors behind the stretched NMRD profile, the distribution of orientationalorder parameters and residence times of buried water used in the NMRD model.
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| 10. |
- Jacobson, Bengt J H, 1962, et al.
(författare)
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Potential effectiveness of a stability control system for passenger cars after an initial side impact
- 2014
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Ingår i: FISITA 2014 World Automotive Congress - Proceedings.
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Konferensbidrag (refereegranskat)abstract
- Vehicle multiple-event accidents constitute 1/4-1/3 of all severe accidents. The present paper studies the control of the vehicle’s abnormal motion after being hit by another vehicle. The potential effectiveness of such a stability control system is estimated through accident data analysis and vehicle dynamics simulation. Only side impacts were simulated, but engineering judgments were made to project the effectiveness potential prediction on the total traffic work. Assuming ESC-like control (closed loop control on yaw rate, using wheel brakes) it is found that the function has potential to mitigate accident for up to 10-9 cars per driven km, or up to 0.1% of the cars in the accident database. While assuming Post Impact Stability Control by steering (closed loop control on yaw angle and path deviation, using steering), the corresponding figures are approximately ten times higher.
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